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Journal Abstract Search

687 related items for PubMed ID: 21058956

  • 1. Challenges of antibacterial discovery revisited.
    Gwynn MN, Portnoy A, Rittenhouse SF, Payne DJ.
    Ann N Y Acad Sci; 2010 Dec; 1213():5-19. PubMed ID: 21058956
    [Abstract] [Full Text] [Related]

  • 2. Bacterial targets to antimicrobial leads and development candidates.
    Rogers BL.
    Curr Opin Drug Discov Devel; 2004 Mar; 7(2):211-22. PubMed ID: 15603255
    [Abstract] [Full Text] [Related]

  • 3. Antibacterial research and development in the 21(st) Century--an industry perspective of the challenges.
    Thomson CJ, Power E, Ruebsamen-Waigmann H, Labischinski H.
    Curr Opin Microbiol; 2004 Oct; 7(5):445-50. PubMed ID: 15451498
    [Abstract] [Full Text] [Related]

  • 4. Postgenomic strategies in antibacterial drug discovery.
    Brötz-Oesterhelt H, Sass P.
    Future Microbiol; 2010 Oct; 5(10):1553-79. PubMed ID: 21073314
    [Abstract] [Full Text] [Related]

  • 5. When will the genomics investment pay off for antibacterial discovery?
    Mills SD.
    Biochem Pharmacol; 2006 Mar 30; 71(7):1096-102. PubMed ID: 16387281
    [Abstract] [Full Text] [Related]

  • 6. Small and lethal: searching for new antibacterial compounds with novel modes of action.
    Pathania R, Brown ED.
    Biochem Cell Biol; 2008 Apr 30; 86(2):111-5. PubMed ID: 18443624
    [Abstract] [Full Text] [Related]

  • 7. Antibacterial drug discovery--then, now and the genomics future.
    Monaghan RL, Barrett JF.
    Biochem Pharmacol; 2006 Mar 30; 71(7):901-9. PubMed ID: 16494849
    [Abstract] [Full Text] [Related]

  • 8. [Development of antituberculous drugs: current status and future prospects].
    Tomioka H, Namba K.
    Kekkaku; 2006 Dec 30; 81(12):753-74. PubMed ID: 17240921
    [Abstract] [Full Text] [Related]

  • 9. Discovery research: the scientific challenge of finding new antibiotics.
    Livermore DM, British Society for Antimicrobial Chemotherapy Working Party on The Urgent Need: Regenerating Antibacterial Drug Discovery and Development.
    J Antimicrob Chemother; 2011 Sep 30; 66(9):1941-4. PubMed ID: 21700626
    [Abstract] [Full Text] [Related]

  • 10. Novel heterodimer antibiotics: a review of recent patent literature.
    Long DD, Marquess DG.
    Future Med Chem; 2009 Sep 30; 1(6):1037-50. PubMed ID: 21425993
    [Abstract] [Full Text] [Related]

  • 11. Structure-based approaches to antibiotic drug discovery.
    Nicola G, Abagyan R.
    Curr Protoc Microbiol; 2009 Feb 30; Chapter 17():Unit17.2. PubMed ID: 19235149
    [Abstract] [Full Text] [Related]

  • 12. Nature's clarion call of antibacterial resistance: are we listening?
    Theuretzbacher U, Toney JH.
    Curr Opin Investig Drugs; 2006 Feb 30; 7(2):158-66. PubMed ID: 16499286
    [Abstract] [Full Text] [Related]

  • 13. Genomic approaches to antibacterial discovery.
    Payne DJ, Gwynn MN, Holmes DJ, Rosenberg M.
    Methods Mol Biol; 2004 Feb 30; 266():231-59. PubMed ID: 15148422
    [Abstract] [Full Text] [Related]

  • 14. Antibacterial drug discovery: is it all downhill from here?
    Projan SJ, Shlaes DM.
    Clin Microbiol Infect; 2004 Nov 30; 10 Suppl 4():18-22. PubMed ID: 15522036
    [Abstract] [Full Text] [Related]

  • 15. Molecular clinical safety intelligence: a system for bridging clinically focused safety knowledge to early-stage drug discovery - the GSK experience.
    Vanderwall DE, Yuen N, Al-Ansari M, Bailey J, Fram D, Green DV, Pickett S, Vitulli G, Luengo JI, Almenoff JS.
    Drug Discov Today; 2011 Aug 30; 16(15-16):646-53. PubMed ID: 21601652
    [Abstract] [Full Text] [Related]

  • 16. Improving lead generation success through integrated methods: transcending 'drug discovery by numbers'.
    Campbell JB.
    IDrugs; 2010 Dec 30; 13(12):874-9. PubMed ID: 21154146
    [Abstract] [Full Text] [Related]

  • 17. Novel trends in high-throughput screening.
    Mayr LM, Bojanic D.
    Curr Opin Pharmacol; 2009 Oct 30; 9(5):580-8. PubMed ID: 19775937
    [Abstract] [Full Text] [Related]

  • 18. Discovery of antibacterial biotin carboxylase inhibitors by virtual screening and fragment-based approaches.
    Mochalkin I, Miller JR, Narasimhan L, Thanabal V, Erdman P, Cox PB, Prasad JV, Lightle S, Huband MD, Stover CK.
    ACS Chem Biol; 2009 Jun 19; 4(6):473-83. PubMed ID: 19413326
    [Abstract] [Full Text] [Related]

  • 19. Exploiting current understanding of antibiotic action for discovery of new drugs.
    Chopra I, Hesse L, O'Neill AJ.
    Symp Ser Soc Appl Microbiol; 2002 Jun 19; (31):4S-15S. PubMed ID: 12481824
    [Abstract] [Full Text] [Related]

  • 20. Late stage antibacterial drugs in the clinical pipeline.
    Projan SJ, Bradford PA.
    Curr Opin Microbiol; 2007 Oct 19; 10(5):441-6. PubMed ID: 17950658
    [Abstract] [Full Text] [Related]

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