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156 related items for PubMed ID: 21070407

  • 1. Functional analysis of folate polyglutamylation and its essential role in plant metabolism and development.
    Mehrshahi P, Gonzalez-Jorge S, Akhtar TA, Ward JL, Santoyo-Castelazo A, Marcus SE, Lara-Núñez A, Ravanel S, Hawkins ND, Beale MH, Barrett DA, Knox JP, Gregory JF, Hanson AD, Bennett MJ, Dellapenna D.
    Plant J; 2010 Oct; 64(2):267-79. PubMed ID: 21070407
    [Abstract] [Full Text] [Related]

  • 2. Folylpoly-gamma-glutamate synthetase: generation of isozymes and the role in one carbon metabolism and antifolate cytotoxicity.
    Qi H, Atkinson I, Xiao S, Choi YJ, Tobimatsu T, Shane B.
    Adv Enzyme Regul; 1999 Oct; 39():263-73. PubMed ID: 10470377
    [Abstract] [Full Text] [Related]

  • 3. The folylpolyglutamate synthetase plastidial isoform is required for postembryonic root development in Arabidopsis.
    Srivastava AC, Ramos-Parra PA, Bedair M, Robledo-Hernández AL, Tang Y, Sumner LW, Díaz de la Garza RI, Blancaflor EB.
    Plant Physiol; 2011 Mar; 155(3):1237-51. PubMed ID: 21233333
    [Abstract] [Full Text] [Related]

  • 4. Folylpoly-γ-glutamate synthetase: A key determinant of folate homeostasis and antifolate resistance in cancer.
    Raz S, Stark M, Assaraf YG.
    Drug Resist Updat; 2016 Sep; 28():43-64. PubMed ID: 27620954
    [Abstract] [Full Text] [Related]

  • 5. Tetrahydrofolate biosynthesis in plants: molecular and functional characterization of dihydrofolate synthetase and three isoforms of folylpolyglutamate synthetase in Arabidopsis thaliana.
    Ravanel S, Cherest H, Jabrin S, Grunwald D, Surdin-Kerjan Y, Douce R, Rébeillé F.
    Proc Natl Acad Sci U S A; 2001 Dec 18; 98(26):15360-5. PubMed ID: 11752472
    [Abstract] [Full Text] [Related]

  • 6. Folate polyglutamylation is involved in chromatin silencing by maintaining global DNA methylation and histone H3K9 dimethylation in Arabidopsis.
    Zhou HR, Zhang FF, Ma ZY, Huang HW, Jiang L, Cai T, Zhu JK, Zhang C, He XJ.
    Plant Cell; 2013 Jul 18; 25(7):2545-59. PubMed ID: 23881414
    [Abstract] [Full Text] [Related]

  • 7. Plastidial Folate Prevents Starch Biosynthesis Triggered by Sugar Influx into Non-Photosynthetic Plastids of Arabidopsis.
    Hayashi M, Tanaka M, Yamamoto S, Nakagawa T, Kanai M, Anegawa A, Ohnishi M, Mimura T, Nishimura M.
    Plant Cell Physiol; 2017 Aug 01; 58(8):1328-1338. PubMed ID: 28586467
    [Abstract] [Full Text] [Related]

  • 8. Regulation of folate and one-carbon metabolism in mammalian cells. II. Effect of folylpoly-gamma-glutamate synthetase substrate specificity and level on folate metabolism and folylpoly-gamma-glutamate specificity of metabolic cycles of one-carbon metabolism.
    Lowe KE, Osborne CB, Lin BF, Kim JS, Hsu JC, Shane B.
    J Biol Chem; 1993 Oct 15; 268(29):21665-73. PubMed ID: 8408019
    [Abstract] [Full Text] [Related]

  • 9. Folylpoly-ɣ-glutamate synthetase association to the cytoskeleton: Implications to folate metabolon compartmentalization.
    Stark M, Raz S, Assaraf YG.
    J Proteomics; 2021 May 15; 239():104169. PubMed ID: 33676037
    [Abstract] [Full Text] [Related]

  • 10. Effect of polyglutamylation of methotrexate on its accumulation and the development of resistance in the protozoan parasite Leishmania.
    El-Fadili A, Richard D, Kündig C, Ouellette M.
    Biochem Pharmacol; 2003 Sep 15; 66(6):999-1008. PubMed ID: 12963486
    [Abstract] [Full Text] [Related]

  • 11. Loss of folylpoly-gamma-glutamate synthetase activity is a dominant mechanism of resistance to polyglutamylation-dependent novel antifolates in multiple human leukemia sublines.
    Liani E, Rothem L, Bunni MA, Smith CA, Jansen G, Assaraf YG.
    Int J Cancer; 2003 Feb 20; 103(5):587-99. PubMed ID: 12494465
    [Abstract] [Full Text] [Related]

  • 12. Characterization of the folylpolyglutamate synthetase gene and polyglutamylation of folates in the protozoan parasite Leishmania.
    El Fadili A, Kündig C, Ouellette M.
    Mol Biochem Parasitol; 2002 Feb 20; 124(1-2):63-71. PubMed ID: 12387851
    [Abstract] [Full Text] [Related]

  • 13. Role of Mitochondrial and Cytosolic Folylpolyglutamate Synthetase in One-Carbon Metabolism and Antitumor Efficacy of Mitochondrial-Targeted Antifolates.
    O'Connor C, Schneider M, Katinas JM, Nayeen MJ, Shah K, Magdum T, Sharma A, Kim S, Bao X, Li J, Dann CE, Gangjee A, Matherly LH, Hou Z.
    Mol Pharmacol; 2024 Sep 17; 106(4):173-187. PubMed ID: 39048308
    [Abstract] [Full Text] [Related]

  • 14. Effects of folate and folylpolyglutamyl synthase modulation on chemosensitivity of breast cancer cells.
    Cho RC, Cole PD, Sohn KJ, Gaisano G, Croxford R, Kamen BA, Kim YI.
    Mol Cancer Ther; 2007 Nov 17; 6(11):2909-20. PubMed ID: 18025275
    [Abstract] [Full Text] [Related]

  • 15. Regulation of folate and one-carbon metabolism in mammalian cells. I. Folate metabolism in Chinese hamster ovary cells expressing Escherichia coli or human folylpoly-gamma-glutamate synthetase activity.
    Osborne CB, Lowe KE, Shane B.
    J Biol Chem; 1993 Oct 15; 268(29):21657-64. PubMed ID: 8408018
    [Abstract] [Full Text] [Related]

  • 16. The plastidial folylpolyglutamate synthetase and root apical meristem maintenance.
    Srivastava AC, Tang Y, de la Garza RI, Blancaflor EB.
    Plant Signal Behav; 2011 May 15; 6(5):751-4. PubMed ID: 21502816
    [Abstract] [Full Text] [Related]

  • 17. Purification and properties of human cytosolic folylpoly-gamma-glutamate synthetase and organization, localization, and differential splicing of its gene.
    Chen L, Qi H, Korenberg J, Garrow TA, Choi YJ, Shane B.
    J Biol Chem; 1996 May 31; 271(22):13077-87. PubMed ID: 8662720
    [Abstract] [Full Text] [Related]

  • 18. The mitochondrial folylpolyglutamate synthetase gene is required for nitrogen utilization during early seedling development in arabidopsis.
    Jiang L, Liu Y, Sun H, Han Y, Li J, Li C, Guo W, Meng H, Li S, Fan Y, Zhang C.
    Plant Physiol; 2013 Feb 31; 161(2):971-89. PubMed ID: 23129207
    [Abstract] [Full Text] [Related]

  • 19. Loss of function of folylpolyglutamate synthetase 1 reduces lignin content and improves cell wall digestibility in Arabidopsis.
    Srivastava AC, Chen F, Ray T, Pattathil S, Peña MJ, Avci U, Li H, Huhman DV, Backe J, Urbanowicz B, Miller JS, Bedair M, Wyman CE, Sumner LW, York WS, Hahn MG, Dixon RA, Blancaflor EB, Tang Y.
    Biotechnol Biofuels; 2015 Feb 31; 8():224. PubMed ID: 26697113
    [Abstract] [Full Text] [Related]

  • 20. Arabidopsis plastidial folylpolyglutamate synthetase is required for seed reserve accumulation and seedling establishment in darkness.
    Meng H, Jiang L, Xu B, Guo W, Li J, Zhu X, Qi X, Duan L, Meng X, Fan Y, Zhang C.
    PLoS One; 2014 Feb 31; 9(7):e101905. PubMed ID: 25000295
    [Abstract] [Full Text] [Related]

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