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214 related items for PubMed ID: 21070747

  • 1. CYP1D1, pseudogenized in human, is expressed and encodes a functional drug-metabolizing enzyme in cynomolgus monkey.
    Uno Y, Uehara S, Murayama N, Yamazaki H.
    Biochem Pharmacol; 2011 Feb 01; 81(3):442-50. PubMed ID: 21070747
    [Abstract] [Full Text] [Related]

  • 2. Discovery of genetic variants in CYP1D1: implication for functional integrity of CYP1D1 in cynomolgus macaques and rhesus macaques.
    Uno Y, Uehara S, Yamazaki H.
    Drug Metab Pharmacokinet; 2011 Feb 01; 26(6):627-31. PubMed ID: 21844658
    [Abstract] [Full Text] [Related]

  • 3. CYP2G2, pseudogenized in human, is expressed in nasal mucosa of cynomolgus monkey and encodes a functional drug-metabolizing enzyme.
    Uno Y, Uehara S, Murayama N, Yamazaki H.
    Drug Metab Dispos; 2011 Apr 01; 39(4):717-23. PubMed ID: 21189332
    [Abstract] [Full Text] [Related]

  • 4. A novel CYP2A26 identified in cynomolgus monkey liver metabolizes coumarin.
    Uehara S, Murayama N, Yamazaki H, Uno Y.
    Xenobiotica; 2010 Sep 01; 40(9):621-9. PubMed ID: 20929430
    [Abstract] [Full Text] [Related]

  • 5. Cynomolgus monkey CYP2D44 newly identified in liver, metabolizes bufuralol, and dextromethorphan.
    Uno Y, Uehara S, Kohara S, Murayama N, Yamazaki H.
    Drug Metab Dispos; 2010 Sep 01; 38(9):1486-92. PubMed ID: 20501912
    [Abstract] [Full Text] [Related]

  • 6. Molecular cloning and functional analysis of cytochrome P450 1A2 from Japanese monkey liver: comparison with marmoset cytochrome P450 1A2.
    Narimatsu S, Oda M, Hichiya H, Isobe T, Asaoka K, Hanioka N, Yamano S, Shinoda S, Yamamoto S.
    Chem Biol Interact; 2005 Feb 28; 152(1):1-12. PubMed ID: 15766918
    [Abstract] [Full Text] [Related]

  • 7. Molecular cloning, expression, and characterization of CYP2D17 from cynomolgus monkey liver.
    Mankowski DC, Laddison KJ, Christopherson PA, Ekins S, Tweedie DJ, Lawton MP.
    Arch Biochem Biophys; 1999 Dec 01; 372(1):189-96. PubMed ID: 10562433
    [Abstract] [Full Text] [Related]

  • 8. CYP2C76, a novel cytochrome P450 in cynomolgus monkey, is a major CYP2C in liver, metabolizing tolbutamide and testosterone.
    Uno Y, Fujino H, Kito G, Kamataki T, Nagata R.
    Mol Pharmacol; 2006 Aug 01; 70(2):477-86. PubMed ID: 16648389
    [Abstract] [Full Text] [Related]

  • 9. Novel cytochrome P450 1 (CYP1) genes in tree shrews are expressed and encode functional drug-metabolizing enzymes.
    Uno Y, Noda Y, Murayama N, Tsukiyama-Kohara K, Yamazaki H.
    Comp Biochem Physiol C Toxicol Pharmacol; 2023 Mar 01; 265():109534. PubMed ID: 36563947
    [Abstract] [Full Text] [Related]

  • 10. Expressed sequence tags from cynomolgus monkey (Macaca fascicularis) liver: a systematic identification of drug-metabolizing enzymes.
    Uno Y, Suzuki Y, Wakaguri H, Sakamoto Y, Sano H, Osada N, Hashimoto K, Sugano S, Inoue I.
    FEBS Lett; 2008 Jan 23; 582(2):351-8. PubMed ID: 18166157
    [Abstract] [Full Text] [Related]

  • 11. Functional characterization of human and cynomolgus monkey cytochrome P450 2E1 enzymes.
    Hanioka N, Yamamoto M, Iwabu H, Jinno H, Tanaka-Kagawa T, Naito S, Shimizu T, Masuda K, Katsu T, Narimatsu S.
    Life Sci; 2007 Oct 27; 81(19-20):1436-45. PubMed ID: 17935737
    [Abstract] [Full Text] [Related]

  • 12. Characterization of cynomolgus monkey cytochrome P450 (CYP) cDNAs: is CYP2C76 the only monkey-specific CYP gene responsible for species differences in drug metabolism?
    Uno Y, Hosaka S, Matsuno K, Nakamura C, Kito G, Kamataki T, Nagata R.
    Arch Biochem Biophys; 2007 Oct 01; 466(1):98-105. PubMed ID: 17689485
    [Abstract] [Full Text] [Related]

  • 13. Cynomolgus monkey (Macaca fascicularis) cathepsin K: cloning, expression, purification, and activation.
    McQueney MS, Feild J, Hanning CR, Brun K, Ramachandran K, Connor J, Drake F, Jones CS, Amegadzie BY.
    Protein Expr Purif; 1998 Dec 01; 14(3):387-94. PubMed ID: 9882573
    [Abstract] [Full Text] [Related]

  • 14. Regional distribution of drug-metabolizing enzyme activities in the liver and small intestine of cynomolgus monkeys.
    Nakanishi Y, Matsushita A, Matsuno K, Iwasaki K, Utoh M, Nakamura C, Uno Y.
    Drug Metab Pharmacokinet; 2011 Jun 01; 26(3):288-94. PubMed ID: 21273732
    [Abstract] [Full Text] [Related]

  • 15. CYP2C19 polymorphisms account for inter-individual variability of drug metabolism in cynomolgus macaques.
    Uno Y, Matsushita A, Shukuya M, Matsumoto Y, Murayama N, Yamazaki H.
    Biochem Pharmacol; 2014 Sep 15; 91(2):242-8. PubMed ID: 25036290
    [Abstract] [Full Text] [Related]

  • 16. Newly identified CYP2C93 is a functional enzyme in rhesus monkey, but not in cynomolgus monkey.
    Uno Y, Uehara S, Kohara S, Iwasaki K, Nagata R, Fukuzaki K, Utoh M, Murayama N, Yamazaki H.
    PLoS One; 2011 Feb 08; 6(2):e16923. PubMed ID: 21347438
    [Abstract] [Full Text] [Related]

  • 17. Characterization of intestinal and hepatic P450 enzymes in cynomolgus monkeys with typical substrates and inhibitors for human P450 enzymes.
    Yoda N, Emoto C, Date S, Kondo S, Miyake M, Nakazato S, Umehara K, Kashiyama E.
    Xenobiotica; 2012 Aug 08; 42(8):719-30. PubMed ID: 22324396
    [Abstract] [Full Text] [Related]

  • 18. Identification and characterization of CYP2C18 in the cynomolgus macaque (Macaca fascicularis).
    Uno Y, Matsuno K, Nakamura C, Utoh M, Yamazaki H.
    J Vet Med Sci; 2010 Feb 08; 72(2):225-8. PubMed ID: 19940391
    [Abstract] [Full Text] [Related]

  • 19. Macaque cytochromes P450: nomenclature, transcript, gene, genomic structure, and function.
    Uno Y, Iwasaki K, Yamazaki H, Nelson DR.
    Drug Metab Rev; 2011 Aug 08; 43(3):346-61. PubMed ID: 21303270
    [Abstract] [Full Text] [Related]

  • 20. Cloning and sequencing of the cynomolgus monkey prostate specific antigen cDNA.
    Marshall DJ, Rudnick KA, Lu J, Snyder LA.
    J Med Primatol; 2006 Feb 08; 35(1):12-7. PubMed ID: 16430490
    [Abstract] [Full Text] [Related]

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