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238 related items for PubMed ID: 2107391
1. Mechanism of the reaction of ebselen with endogenous thiols: dihydrolipoate is a better cofactor than glutathione in the peroxidase activity of ebselen. Haenen GR, De Rooij BM, Vermeulen NP, Bast A. Mol Pharmacol; 1990 Mar; 37(3):412-22. PubMed ID: 2107391 [Abstract] [Full Text] [Related]
2. Glutathione peroxidase (GPx)-like antioxidant activity of the organoselenium drug ebselen: unexpected complications with thiol exchange reactions. Sarma BK, Mugesh G. J Am Chem Soc; 2005 Aug 17; 127(32):11477-85. PubMed ID: 16089478 [Abstract] [Full Text] [Related]
9. Synthesis, structure, and glutathione peroxidase-like activity of amino acid containing ebselen analogues and diaryl diselenides. Selvakumar K, Shah P, Singh HB, Butcher RJ. Chemistry; 2011 Nov 04; 17(45):12741-55. PubMed ID: 21956838 [Abstract] [Full Text] [Related]
10. A novel antioxidant mechanism of ebselen involving ebselen diselenide, a substrate of mammalian thioredoxin and thioredoxin reductase. Zhao R, Holmgren A. J Biol Chem; 2002 Oct 18; 277(42):39456-62. PubMed ID: 12177067 [Abstract] [Full Text] [Related]
11. Ebselen: a substrate for human thioredoxin reductase strongly stimulating its hydroperoxide reductase activity and a superfast thioredoxin oxidant. Zhao R, Masayasu H, Holmgren A. Proc Natl Acad Sci U S A; 2002 Jun 25; 99(13):8579-84. PubMed ID: 12070343 [Abstract] [Full Text] [Related]
12. Ebselen has dehydroascorbate reductase and thioltransferase-like activities. Jung CH, Washburn MP, Wells WW. Biochem Biophys Res Commun; 2002 Mar 01; 291(3):550-3. PubMed ID: 11855823 [Abstract] [Full Text] [Related]
13. Kinetic mechanism and substrate specificity of glutathione peroxidase activity of ebselen (PZ51). Maiorino M, Roveri A, Coassin M, Ursini F. Biochem Pharmacol; 1988 Jun 01; 37(11):2267-71. PubMed ID: 3377822 [Abstract] [Full Text] [Related]
14. Functional mimics of glutathione peroxidase: bioinspired synthetic antioxidants. Bhabak KP, Mugesh G. Acc Chem Res; 2010 Nov 16; 43(11):1408-19. PubMed ID: 20690615 [Abstract] [Full Text] [Related]
16. Reaction kinetics and targeting to cellular glutathione S-transferase of the glutathione peroxidase mimetic PhSeZnCl and its D,L-polylactide microparticle formulation. Bartolini D, Piroddi M, Tidei C, Giovagnoli S, Pietrella D, Manevich Y, Tew KD, Giustarini D, Rossi R, Townsend DM, Santi C, Galli F. Free Radic Biol Med; 2015 Jan 16; 78():56-65. PubMed ID: 25452145 [Abstract] [Full Text] [Related]
17. Synthesis and antioxidant activity of peptide-based ebselen analogues. Satheeshkumar K, Mugesh G. Chemistry; 2011 Apr 18; 17(17):4849-57. PubMed ID: 21400619 [Abstract] [Full Text] [Related]
18. Inhibition of endothelial nitric oxide synthase by ebselen. Prevention by thiols suggests the inactivation by ebselen of a critical thiol essential for the catalytic activity of nitric oxide synthase. Zembowicz A, Hatchett RJ, Radziszewski W, Gryglewski RJ. J Pharmacol Exp Ther; 1993 Dec 18; 267(3):1112-8. PubMed ID: 7505326 [Abstract] [Full Text] [Related]
19. Ebselen induces apoptosis in HepG(2) cells through rapid depletion of intracellular thiols. Yang CF, Shen HM, Ong CN. Arch Biochem Biophys; 2000 Feb 15; 374(2):142-52. PubMed ID: 10666292 [Abstract] [Full Text] [Related]
20. Acetaldehyde does not inhibit glutathione peroxidase and glutathione reductase from mouse liver in vitro. Pivetta LA, Dafre AL, Zeni G, Rocha JB, Farina M. Chem Biol Interact; 2006 Feb 25; 159(3):196-204. PubMed ID: 16387289 [Abstract] [Full Text] [Related] Page: [Next] [New Search]