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Journal Abstract Search

331 related items for PubMed ID: 21074444

  • 1. Synthesis of 4β-N-polyaromatic substituted podophyllotoxins: DNA topoisomerase inhibition, anticancer and apoptosis-inducing activities.
    Kamal A, Kumar BA, Suresh P, Agrawal SK, Chashoo G, Singh SK, Saxena AK.
    Bioorg Med Chem; 2010 Dec 15; 18(24):8493-500. PubMed ID: 21074444
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  • 2. Synthesis and biological evaluation of new 4beta-anilino- and 4beta-imido-substituted podophyllotoxin congeners.
    Kamal A, Gayatri NL, Reddy DR, Mohan Reddy PS, Arifuddin M, Dastidar SG, Kondapi AK, Rajkumar M.
    Bioorg Med Chem; 2005 Nov 15; 13(22):6218-25. PubMed ID: 16061385
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  • 3. An efficient one-pot synthesis of benzothiazolo-4β-anilino-podophyllotoxin congeners: DNA topoisomerase-II inhibition and anticancer activity.
    Kamal A, Kumar BA, Suresh P, Shankaraiah N, Kumar MS.
    Bioorg Med Chem Lett; 2011 Jan 01; 21(1):350-3. PubMed ID: 21144748
    [Abstract] [Full Text] [Related]

  • 4. Synthesis and biological evaluation of 4β-sulphonamido and 4β-[(4'-sulphonamido)benzamide]podophyllotoxins as DNA topoisomerase-IIα and apoptosis inducing agents.
    Kamal A, Suresh P, Ramaiah MJ, Mallareddy A, Imthiajali S, Pushpavalli SN, Lavanya A, Pal-Bhadra M.
    Bioorg Med Chem; 2012 Mar 15; 20(6):2054-66. PubMed ID: 22364746
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  • 5. Synthesis and biological evaluation of 4beta-[(4-substituted)-1,2,3-triazol-1-yl]podophyllotoxins as potential anticancer agents.
    Reddy PB, Agrawal SK, Singh S, Bhat BA, Saxena AK, Kumar HM, Qazi GN.
    Chem Biodivers; 2008 Sep 15; 5(9):1792-802. PubMed ID: 18816530
    [Abstract] [Full Text] [Related]

  • 6. One-pot synthesis of podophyllotoxin-thiourea congeners by employing NH₂SO₃H/NaI: Anticancer activity, DNA topoisomerase-II inhibition, and apoptosis inducing agents.
    Shankaraiah N, Kumar NP, Amula SB, Nekkanti S, Jeengar MK, Naidu VG, Reddy TS, Kamal A.
    Bioorg Med Chem Lett; 2015 Oct 01; 25(19):4239-44. PubMed ID: 26292628
    [Abstract] [Full Text] [Related]

  • 7. Synthesis of 4β-carbamoyl epipodophyllotoxins as potential antitumour agents.
    Kamal A, Kumar BA, Suresh P, Juvekar A, Zingde S.
    Bioorg Med Chem; 2011 May 01; 19(9):2975-9. PubMed ID: 21489802
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  • 8. 4β-[4'-(1-(Aryl)ureido)benzamide]podophyllotoxins as DNA topoisomerase I and IIα inhibitors and apoptosis inducing agents.
    Kamal A, Suresh P, Ramaiah MJ, Srinivasa Reddy T, Kapavarapu RK, Rao BN, Imthiajali S, Lakshminarayan Reddy T, Pushpavalli SN, Shankaraiah N, Pal-Bhadra M.
    Bioorg Med Chem; 2013 Sep 01; 21(17):5198-208. PubMed ID: 23849207
    [Abstract] [Full Text] [Related]

  • 9. Design, synthesis, and biological testing of 4beta-[(4-substituted)-1,2,3-triazol-1-yl]podophyllotoxin analogues as antitumor agents.
    Reddy PB, Paul DV, Agrawal SK, Saxena AK, Kumar HM, Qazi GN.
    Arch Pharm (Weinheim); 2008 Feb 01; 341(2):126-31. PubMed ID: 18214838
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  • 12. 4β-amidotriazole linked podophyllotoxin congeners: DNA topoisomerase-IIα inhibition and potential anticancer agents for prostate cancer.
    Reddy VG, Bonam SR, Reddy TS, Akunuri R, Naidu VGM, Nayak VL, Bhargava SK, Kumar HMS, Srihari P, Kamal A.
    Eur J Med Chem; 2018 Jan 20; 144():595-611. PubMed ID: 29289884
    [Abstract] [Full Text] [Related]

  • 13. Studies on novel 4beta-[(4-substituted)-1,2,3-triazol-1-yl] podophyllotoxins as potential anticancer agents.
    Bhat BA, Reddy PB, Agrawal SK, Saxena AK, Kumar HM, Qazi GN.
    Eur J Med Chem; 2008 Oct 20; 43(10):2067-72. PubMed ID: 17988764
    [Abstract] [Full Text] [Related]

  • 14. Synthesis and evaluation of aroylthiourea derivatives of 4-β-amino-4'-O-demethyl-4-desoxypodophyllotoxin as novel topoisomerase II inhibitors.
    Zhao Y, Ge CW, Wu ZH, Wang CN, Fang JH, Zhu L.
    Eur J Med Chem; 2011 Mar 20; 46(3):901-6. PubMed ID: 21277655
    [Abstract] [Full Text] [Related]

  • 15. N-fused imidazoles as novel anticancer agents that inhibit catalytic activity of topoisomerase IIα and induce apoptosis in G1/S phase.
    Baviskar AT, Madaan C, Preet R, Mohapatra P, Jain V, Agarwal A, Guchhait SK, Kundu CN, Banerjee UC, Bharatam PV.
    J Med Chem; 2011 Jul 28; 54(14):5013-30. PubMed ID: 21644529
    [Abstract] [Full Text] [Related]

  • 16. A rational design strategy of the novel topoisomerase II inhibitors for the synthesis of the 4-O-(2-pyrazinecarboxylic)-4'-demethylepipodophyllotoxin with antitumor activity by diminishing the relaxation reaction of topoisomerase II-DNA decatenation.
    Zhao W, Chen L, Li HM, Wang DJ, Li DS, Chen T, Yuan ZP, Tang YJ.
    Bioorg Med Chem; 2014 Jun 01; 22(11):2998-3007. PubMed ID: 24775914
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  • 17. Synthesis and evaluation of novel podophyllotoxin analogs.
    Li J, Hua HM, Tang YB, Zhang S, Ohkoshi E, Lee KH, Xiao Zy.
    Bioorg Med Chem Lett; 2012 Jul 01; 22(13):4293-5. PubMed ID: 22658864
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  • 19. Synthesis and biological evaluation of benzo[a]phenazine derivatives as a dual inhibitor of topoisomerase I and II.
    Zhuo ST, Li CY, Hu MH, Chen SB, Yao PF, Huang SL, Ou TM, Tan JH, An LK, Li D, Gu LQ, Huang ZS.
    Org Biomol Chem; 2013 Jun 28; 11(24):3989-4005. PubMed ID: 23657605
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