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389 related items for PubMed ID: 21075154

  • 1. Activated MAO-B in the brain of Alzheimer patients, demonstrated by [11C]-L-deprenyl using whole hemisphere autoradiography.
    Gulyás B, Pavlova E, Kása P, Gulya K, Bakota L, Várszegi S, Keller E, Horváth MC, Nag S, Hermecz I, Magyar K, Halldin C.
    Neurochem Int; 2011 Jan; 58(1):60-8. PubMed ID: 21075154
    [Abstract] [Full Text] [Related]

  • 2. In vivo measurement of brain monoamine oxidase B occupancy by rasagiline, using (11)C-l-deprenyl and PET.
    Freedman NM, Mishani E, Krausz Y, Weininger J, Lester H, Blaugrund E, Ehrlich D, Chisin R.
    J Nucl Med; 2005 Oct; 46(10):1618-24. PubMed ID: 16204711
    [Abstract] [Full Text] [Related]

  • 3. Evidence for astrocytosis in ALS demonstrated by [11C](L)-deprenyl-D2 PET.
    Johansson A, Engler H, Blomquist G, Scott B, Wall A, Aquilonius SM, Långström B, Askmark H.
    J Neurol Sci; 2007 Apr 15; 255(1-2):17-22. PubMed ID: 17346749
    [Abstract] [Full Text] [Related]

  • 4. Multitracer Approach to Understanding the Complexity of Reactive Astrogliosis in Alzheimer's Brains.
    Fontana IC, Kumar A, Okamura N, Nordberg A.
    ACS Chem Neurosci; 2024 Jan 17; 15(2):328-336. PubMed ID: 38133820
    [Abstract] [Full Text] [Related]

  • 5. Monoamine oxidase B inhibitor, selegiline, reduces 18F-THK5351 uptake in the human brain.
    Ng KP, Pascoal TA, Mathotaarachchi S, Therriault J, Kang MS, Shin M, Guiot MC, Guo Q, Harada R, Comley RA, Massarweh G, Soucy JP, Okamura N, Gauthier S, Rosa-Neto P.
    Alzheimers Res Ther; 2017 Mar 31; 9(1):25. PubMed ID: 28359327
    [Abstract] [Full Text] [Related]

  • 6. Comparative binding properties of the tau PET tracers THK5117, THK5351, PBB3, and T807 in postmortem Alzheimer brains.
    Lemoine L, Gillberg PG, Svedberg M, Stepanov V, Jia Z, Huang J, Nag S, Tian H, Ghetti B, Okamura N, Higuchi M, Halldin C, Nordberg A.
    Alzheimers Res Ther; 2017 Dec 11; 9(1):96. PubMed ID: 29229003
    [Abstract] [Full Text] [Related]

  • 7. PET imaging of monoamine oxidase B in peripheral organs in humans.
    Fowler JS, Logan J, Wang GJ, Volkow ND, Zhu W, Franceschi D, Pappas N, Ferrieri R, Shea C, Garza V, Xu Y, MacGregor RR, Schlyer D, Gatley SJ, Ding YS, Alexoff D.
    J Nucl Med; 2002 Oct 11; 43(10):1331-8. PubMed ID: 12368371
    [Abstract] [Full Text] [Related]

  • 8. Visualization of brain monoamine oxidase B (MAO-B) in dementia of Alzheimer's type by means of large cryosection autoradiography: a pilot study.
    Jossan SS, Gillberg PG, Karlsson I, Gottfries CG, Oreland L.
    J Neural Transm Suppl; 1990 Oct 11; 32():61-5. PubMed ID: 2128513
    [Abstract] [Full Text] [Related]

  • 9. A comparative autoradiography study in post mortem whole hemisphere human brain slices taken from Alzheimer patients and age-matched controls using two radiolabelled DAA1106 analogues with high affinity to the peripheral benzodiazepine receptor (PBR) system.
    Gulyás B, Makkai B, Kása P, Gulya K, Bakota L, Várszegi S, Beliczai Z, Andersson J, Csiba L, Thiele A, Dyrks T, Suhara T, Suzuki K, Higuchi M, Halldin C.
    Neurochem Int; 2009 Jan 11; 54(1):28-36. PubMed ID: 18984021
    [Abstract] [Full Text] [Related]

  • 10. ³H-deprenyl and ³H-PIB autoradiography show different laminar distributions of astroglia and fibrillar β-amyloid in Alzheimer brain.
    Marutle A, Gillberg PG, Bergfors A, Yu W, Ni R, Nennesmo I, Voytenko L, Nordberg A.
    J Neuroinflammation; 2013 Jul 23; 10():90. PubMed ID: 23880036
    [Abstract] [Full Text] [Related]

  • 11. The pro-psychotic metabotropic glutamate receptor compounds fenobam and AZD9272 share binding sites with monoamine oxidase-B inhibitors in humans.
    Varnäs K, Cselényi Z, Arakawa R, Nag S, Stepanov V, Moein MM, Johnström P, Kingston L, Elmore CS, Halldin C, Farde L.
    Neuropharmacology; 2020 Jan 01; 162():107809. PubMed ID: 31589885
    [Abstract] [Full Text] [Related]

  • 12. Synthesis of three novel fluorine-18 labeled analogues of L-deprenyl for positron emission tomography (PET) studies of monoamine oxidase B (MAO-B).
    Nag S, Lehmann L, Heinrich T, Thiele A, Kettschau G, Nakao R, Gulyás B, Halldin C.
    J Med Chem; 2011 Oct 27; 54(20):7023-9. PubMed ID: 21923198
    [Abstract] [Full Text] [Related]

  • 13. First-in-Humans Evaluation of 18F-SMBT-1, a Novel 18F-Labeled Monoamine Oxidase-B PET Tracer for Imaging Reactive Astrogliosis.
    Villemagne VL, Harada R, Doré V, Furumoto S, Mulligan R, Kudo Y, Burnham S, Krishnadas N, Bozinovski S, Huang K, Lopresti BJ, Yanai K, Rowe CC, Okamura N.
    J Nucl Med; 2022 Oct 27; 63(10):1551-1559. PubMed ID: 35086898
    [Abstract] [Full Text] [Related]

  • 14. Astroglial Responses to Amyloid-Beta Progression in a Mouse Model of Alzheimer's Disease.
    Olsen M, Aguilar X, Sehlin D, Fang XT, Antoni G, Erlandsson A, Syvänen S.
    Mol Imaging Biol; 2018 Aug 27; 20(4):605-614. PubMed ID: 29297157
    [Abstract] [Full Text] [Related]

  • 15. Synthesis and evaluation of [¹⁸F]fluororasagiline, a novel positron emission tomography (PET) radioligand for monoamine oxidase B (MAO-B).
    Nag S, Lehmann L, Kettschau G, Heinrich T, Thiele A, Varrone A, Gulyas B, Halldin C.
    Bioorg Med Chem; 2012 May 01; 20(9):3065-71. PubMed ID: 22436387
    [Abstract] [Full Text] [Related]

  • 16. Selective reduction of radiotracer trapping by deuterium substitution: comparison of carbon-11-L-deprenyl and carbon-11-deprenyl-D2 for MAO B mapping.
    Fowler JS, Wang GJ, Logan J, Xie S, Volkow ND, MacGregor RR, Schlyer DJ, Pappas N, Alexoff DL, Patlak C.
    J Nucl Med; 1995 Jul 01; 36(7):1255-62. PubMed ID: 7790952
    [Abstract] [Full Text] [Related]

  • 17. In Vivo and In Vitro Characterization of a Novel MAO-B Inhibitor Radioligand, 18F-Labeled Deuterated Fluorodeprenyl.
    Nag S, Fazio P, Lehmann L, Kettschau G, Heinrich T, Thiele A, Svedberg M, Amini N, Leesch S, Catafau AM, Hannestad J, Varrone A, Halldin C.
    J Nucl Med; 2016 Feb 01; 57(2):315-20. PubMed ID: 26585057
    [Abstract] [Full Text] [Related]

  • 18. Assessment of MAO-B occupancy in the brain with PET and [11C]-L-deprenyl-D2: a dose-finding study with a novel MAO-B inhibitor, EVT 301.
    Hirvonen J, Kailajärvi M, Haltia T, Koskimies S, Någren K, Virsu P, Oikonen V, Sipilä H, Ruokoniemi P, Virtanen K, Scheinin M, Rinne JO.
    Clin Pharmacol Ther; 2009 May 01; 85(5):506-12. PubMed ID: 19129751
    [Abstract] [Full Text] [Related]

  • 19. Monoamine oxidase activity and monoamine metabolism in brains of parkinsonian patients treated with l-deprenyl.
    Riederer P, Youdim MB.
    J Neurochem; 1986 May 01; 46(5):1359-65. PubMed ID: 2420928
    [Abstract] [Full Text] [Related]

  • 20. In vitro Characterization of the Regional Binding Distribution of Amyloid PET Tracer Florbetaben and the Glia Tracers Deprenyl and PK11195 in Autopsy Alzheimer's Brain Tissue.
    Ni R, Röjdner J, Voytenko L, Dyrks T, Thiele A, Marutle A, Nordberg A.
    J Alzheimers Dis; 2021 May 01; 80(4):1723-1737. PubMed ID: 33749648
    [Abstract] [Full Text] [Related]

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