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Pubmed for Handhelds

PUBMED FOR HANDHELDS

Journal Abstract Search

106 related items for PubMed ID: 21075630

  • 1. Design, synthesis, and structure-activity relationships of indole-3-heterocycles as agonists of the CB1 receptor.
    Morrison AJ, Adam JM, Baker JA, Campbell RA, Clark JK, Cottney JE, Deehan M, Easson AM, Fields R, Francis S, Jeremiah F, Keddie N, Kiyoi T, McArthur DR, Meyer K, Ratcliffe PD, Schulz J, Wishart G, Yoshiizumi K.
    Bioorg Med Chem Lett; 2011 Jan 01; 21(1):506-9. PubMed ID: 21075630
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  • 2. Design, synthesis and structure-activity relationships of (indo-3-yl) heterocyclic derivatives as agonists of the CB1 receptor. Discovery of a clinical candidate.
    Ratcliffe P, Adam JM, Baker J, Bursi R, Campbell R, Clark JK, Cottney JE, Deehan M, Easson AM, Ecker D, Edwards D, Epemolu O, Evans L, Fields R, Francis S, Harradine P, Jeremiah F, Kiyoi T, McArthur D, Morrison A, Passier P, Pick J, Schnabel PG, Schulz J, Steinbrede H, Walker G, Westwood P, Wishart G, Udo de Haes J.
    Bioorg Med Chem Lett; 2011 Apr 15; 21(8):2541-6. PubMed ID: 21411321
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  • 8. Design, synthesis, and structure-activity relationship study of bicyclic piperazine analogs of indole-3-carboxamides as novel cannabinoid CB1 receptor agonists.
    Moir EM, Yoshiizumi K, Cairns J, Cowley P, Ferguson M, Jeremiah F, Kiyoi T, Morphy R, Tierney J, Wishart G, York M, Baker J, Cottney JE, Houghton AK, McPhail P, Osprey A, Walker G, Adam JM.
    Bioorg Med Chem Lett; 2010 Dec 15; 20(24):7327-30. PubMed ID: 21074434
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  • 11. Potent cannabinergic indole analogues as radioiodinatable brain imaging agents for the CB1 cannabinoid receptor.
    Deng H, Gifford AN, Zvonok AM, Cui G, Li X, Fan P, Deschamps JR, Flippen-Anderson JL, Gatley SJ, Makriyannis A.
    J Med Chem; 2005 Oct 06; 48(20):6386-92. PubMed ID: 16190764
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  • 13. Heterocyclic 1,7-disubstituted indole sulfonamides are potent and selective human EP3 receptor antagonists.
    Hategan G, Polozov AM, Zeller W, Cao H, Mishra RK, Kiselyov AS, Ramirez J, Halldorsdottir G, Andrésson T, Gurney ME, Singh J.
    Bioorg Med Chem Lett; 2009 Dec 01; 19(23):6797-800. PubMed ID: 19836233
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  • 17. Synthesis and structure-activity relationship of a novel series of aminoalkylindoles with potential for imaging the neuronal cannabinoid receptor by positron emission tomography.
    Willis PG, Pavlova OA, Chefer SI, Vaupel DB, Mukhin AG, Horti AG.
    J Med Chem; 2005 Sep 08; 48(18):5813-22. PubMed ID: 16134948
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  • 18. Pharmacokinetic optimisation of novel indole-2-carboxamide cannabinoid CB1 antagonists.
    Cowley PM, Baker J, Buchanan KI, Carlyle I, Clark JK, Clarkson TR, Deehan M, Edwards D, Kiyoi Y, Martin I, Osbourn D, Walker G, Ward N, Wishart G.
    Bioorg Med Chem Lett; 2011 Apr 01; 21(7):2034-9. PubMed ID: 21334892
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  • 19. Discovery and evaluation of potent P1 aryl heterocycle-based thrombin inhibitors.
    Young MB, Barrow JC, Glass KL, Lundell GF, Newton CL, Pellicore JM, Rittle KE, Selnick HG, Stauffer KJ, Vacca JP, Williams PD, Bohn D, Clayton FC, Cook JJ, Krueger JA, Kuo LC, Lewis SD, Lucas BJ, McMasters DR, Miller-Stein C, Pietrak BL, Wallace AA, White RB, Wong B, Yan Y, Nantermet PG.
    J Med Chem; 2004 Jun 03; 47(12):2995-3008. PubMed ID: 15163182
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  • 20. Discovery of a novel class of selective human CB1 inverse agonists.
    Foloppe N, Allen NH, Bentley CH, Brooks TD, Kennett G, Knight AR, Leonardi S, Misra A, Monck NJ, Sellwood DM.
    Bioorg Med Chem Lett; 2008 Feb 01; 18(3):1199-206. PubMed ID: 18083560
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