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380 related items for PubMed ID: 21084381

  • 1. Signaling from the human melanocortin 1 receptor to ERK1 and ERK2 mitogen-activated protein kinases involves transactivation of cKIT.
    Herraiz C, Journé F, Abdel-Malek Z, Ghanem G, Jiménez-Cervantes C, García-Borrón JC.
    Mol Endocrinol; 2011 Jan; 25(1):138-56. PubMed ID: 21084381
    [Abstract] [Full Text] [Related]

  • 2. Functional status and relationships of melanocortin 1 receptor signaling to the cAMP and extracellular signal-regulated protein kinases 1 and 2 pathways in human melanoma cells.
    Herraiz C, Journé F, Ghanem G, Jiménez-Cervantes C, García-Borrón JC.
    Int J Biochem Cell Biol; 2012 Dec; 44(12):2244-52. PubMed ID: 23000456
    [Abstract] [Full Text] [Related]

  • 3. Melanocortin 1 receptor mutations impact differentially on signalling to the cAMP and the ERK mitogen-activated protein kinase pathways.
    Herraiz C, Jiménez-Cervantes C, Zanna P, García-Borrón JC.
    FEBS Lett; 2009 Oct 06; 583(19):3269-74. PubMed ID: 19755124
    [Abstract] [Full Text] [Related]

  • 4. Role of G protein-coupled receptor kinases in the homologous desensitization of the human and mouse melanocortin 1 receptors.
    Sánchez-Más J, Guillo LA, Zanna P, Jiménez-Cervantes C, García-Borrón JC.
    Mol Endocrinol; 2005 Apr 06; 19(4):1035-48. PubMed ID: 15650023
    [Abstract] [Full Text] [Related]

  • 5. Functional Characterization of MC1R-TUBB3 Intergenic Splice Variants of the Human Melanocortin 1 Receptor.
    Herraiz C, Olivares C, Castejón-Griñán M, Abrisqueta M, Jiménez-Cervantes C, García-Borrón JC.
    PLoS One; 2015 Apr 06; 10(12):e0144757. PubMed ID: 26657157
    [Abstract] [Full Text] [Related]

  • 6. Human melanocytes expressing MC1R variant alleles show impaired activation of multiple signaling pathways.
    Newton RA, Roberts DW, Leonard JH, Sturm RA.
    Peptides; 2007 Dec 06; 28(12):2387-96. PubMed ID: 18006116
    [Abstract] [Full Text] [Related]

  • 7. The α-melanocyte stimulating hormone/peroxisome proliferator activated receptor-γ pathway down-regulates proliferation in melanoma cell lines.
    Flori E, Rosati E, Cardinali G, Kovacs D, Bellei B, Picardo M, Maresca V.
    J Exp Clin Cancer Res; 2017 Oct 11; 36(1):142. PubMed ID: 29020973
    [Abstract] [Full Text] [Related]

  • 8. Cyclic AMP (cAMP) signaling in melanocytes and melanoma.
    Rodríguez CI, Setaluri V.
    Arch Biochem Biophys; 2014 Dec 01; 563():22-7. PubMed ID: 25017568
    [Abstract] [Full Text] [Related]

  • 9. Melanocortins and the melanocortin 1 receptor, moving translationally towards melanoma prevention.
    Abdel-Malek ZA, Swope VB, Starner RJ, Koikov L, Cassidy P, Leachman S.
    Arch Biochem Biophys; 2014 Dec 01; 563():4-12. PubMed ID: 25017567
    [Abstract] [Full Text] [Related]

  • 10. Defining MC1R regulation in human melanocytes by its agonist α-melanocortin and antagonists agouti signaling protein and β-defensin 3.
    Swope VB, Jameson JA, McFarland KL, Supp DM, Miller WE, McGraw DW, Patel MA, Nix MA, Millhauser GL, Babcock GF, Abdel-Malek ZA.
    J Invest Dermatol; 2012 Sep 01; 132(9):2255-62. PubMed ID: 22572817
    [Abstract] [Full Text] [Related]

  • 11. Melanocytes expressing MC1R polymorphisms associated with red hair color have altered MSH-ligand activated pigmentary responses in coculture with keratinocytes.
    Roberts DW, Newton RA, Leonard JH, Sturm RA.
    J Cell Physiol; 2008 May 01; 215(2):344-55. PubMed ID: 17960564
    [Abstract] [Full Text] [Related]

  • 12. Rate limiting factors in melanocortin 1 receptor signalling through the cAMP pathway.
    Más JS, Gerritsen I, Hahmann C, Jiménez-Cervantes C, García-Borrón JC.
    Pigment Cell Res; 2003 Oct 01; 16(5):540-7. PubMed ID: 12950734
    [Abstract] [Full Text] [Related]

  • 13. Alpha-melanocyte-stimulating hormone suppresses oxidative stress through a p53-mediated signaling pathway in human melanocytes.
    Kadekaro AL, Chen J, Yang J, Chen S, Jameson J, Swope VB, Cheng T, Kadakia M, Abdel-Malek Z.
    Mol Cancer Res; 2012 Jun 01; 10(6):778-86. PubMed ID: 22622028
    [Abstract] [Full Text] [Related]

  • 14. Agonist-independent, high constitutive activity of the human melanocortin 1 receptor.
    Sánchez-Más J, Hahmann C, Gerritsen I, García-Borrón JC, Jiménez-Cervantes C.
    Pigment Cell Res; 2004 Aug 01; 17(4):386-95. PubMed ID: 15250941
    [Abstract] [Full Text] [Related]

  • 15. Cyclic AMP signaling reduces sirtuin 6 expression in non-small cell lung cancer cells by promoting ubiquitin-proteasomal degradation via inhibition of the Raf-MEK-ERK (Raf/mitogen-activated extracellular signal-regulated kinase/extracellular signal-regulated kinase) pathway.
    Kim EJ, Juhnn YS.
    J Biol Chem; 2015 Apr 10; 290(15):9604-13. PubMed ID: 25713071
    [Abstract] [Full Text] [Related]

  • 16. cAMP-independent non-pigmentary actions of variant melanocortin 1 receptor: AKT-mediated activation of protective responses to oxidative DNA damage.
    Castejón-Griñán M, Herraiz C, Olivares C, Jiménez-Cervantes C, García-Borrón JC.
    Oncogene; 2018 Jul 10; 37(27):3631-3646. PubMed ID: 29622793
    [Abstract] [Full Text] [Related]

  • 17. A Side-by-Side Comparison of Wildtype and Variant Melanocortin 1 Receptor Signaling with Emphasis on Protection against Oxidative Damage to DNA.
    Cerdido S, Sánchez-Beltrán J, Lambertos A, Abrisqueta M, Padilla L, Herraiz C, Olivares C, Jiménez-Cervantes C, García-Borrón JC.
    Int J Mol Sci; 2023 Sep 21; 24(18):. PubMed ID: 37762683
    [Abstract] [Full Text] [Related]

  • 18. The E92K melanocortin 1 receptor mutant induces cAMP production and arrestin recruitment but not ERK activity indicating biased constitutive signaling.
    Benned-Jensen T, Mokrosinski J, Rosenkilde MM.
    PLoS One; 2011 Sep 21; 6(9):e24644. PubMed ID: 21931793
    [Abstract] [Full Text] [Related]

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