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Journal Abstract Search

189 related items for PubMed ID: 21087115

  • 1. Application of cytochrome P450 BM3 mutants as biocatalysts for the profiling of estrogen receptor binding metabolites of the mycotoxin zearalenone.
    Reinen J, Kalma LL, Begheijn S, Heus F, Commandeur JN, Vermeulen NP.
    Xenobiotica; 2011 Jan; 41(1):59-70. PubMed ID: 21087115
    [Abstract] [Full Text] [Related]

  • 2. Novel oxidative metabolites of the mycoestrogen zearalenone in vitro.
    Pfeiffer E, Heyting A, Metzler M.
    Mol Nutr Food Res; 2007 Jul; 51(7):867-71. PubMed ID: 17579896
    [Abstract] [Full Text] [Related]

  • 3. Aromatic hydroxylation is a major metabolic pathway of the mycotoxin zearalenone in vitro.
    Pfeiffer E, Hildebrand A, Damm G, Rapp A, Cramer B, Humpf HU, Metzler M.
    Mol Nutr Food Res; 2009 Sep; 53(9):1123-33. PubMed ID: 19655315
    [Abstract] [Full Text] [Related]

  • 4. Metabolic profiling of endocrine-disrupting compounds by on-line cytochrome p450 bioreaction coupled to on-line receptor affinity screening.
    Van Liempd SM, Kool J, Meerman JH, Irth H, Vermeulen NP.
    Chem Res Toxicol; 2007 Dec; 20(12):1825-32. PubMed ID: 17975887
    [Abstract] [Full Text] [Related]

  • 5. On-line formation, separation, and estrogen receptor affinity screening of cytochrome P450-derived metabolites of selective estrogen receptor modulators.
    van Liempd SM, Kool J, Niessen WM, van Elswijk DE, Irth H, Vermeulen NP.
    Drug Metab Dispos; 2006 Sep; 34(9):1640-9. PubMed ID: 16790557
    [Abstract] [Full Text] [Related]

  • 6. Glucuronidation of zearalenone, zeranol and four metabolites in vitro: formation of glucuronides by various microsomes and human UDP-glucuronosyltransferase isoforms.
    Pfeiffer E, Hildebrand A, Mikula H, Metzler M.
    Mol Nutr Food Res; 2010 Oct; 54(10):1468-76. PubMed ID: 20397195
    [Abstract] [Full Text] [Related]

  • 7. In vitro cytochrome p450 formation of a mono-hydroxylated metabolite of zearalenone exhibiting estrogenic activities: possible occurrence of this metabolite in vivo.
    Bravin F, Duca RC, Balaguer P, Delaforge M.
    Int J Mol Sci; 2009 Apr 21; 10(4):1824-37. PubMed ID: 19468341
    [Abstract] [Full Text] [Related]

  • 8. Endocrine disrupting effects of zearalenone, alpha- and beta-zearalenol at the level of nuclear receptor binding and steroidogenesis.
    Frizzell C, Ndossi D, Verhaegen S, Dahl E, Eriksen G, Sørlie M, Ropstad E, Muller M, Elliott CT, Connolly L.
    Toxicol Lett; 2011 Oct 10; 206(2):210-7. PubMed ID: 21803136
    [Abstract] [Full Text] [Related]

  • 9. Genotoxicity and inactivation of catechol metabolites of the mycotoxin zearalenone.
    Fleck SC, Hildebrand AA, Müller E, Pfeiffer E, Metzler M.
    Mycotoxin Res; 2012 Nov 10; 28(4):267-73. PubMed ID: 23606198
    [Abstract] [Full Text] [Related]

  • 10. Application of engineered cytochrome P450 mutants as biocatalysts for the synthesis of benzylic and aromatic metabolites of fenamic acid NSAIDs.
    Venkataraman H, Verkade-Vreeker MC, Capoferri L, Geerke DP, Vermeulen NP, Commandeur JN.
    Bioorg Med Chem; 2014 Oct 15; 22(20):5613-20. PubMed ID: 24999003
    [Abstract] [Full Text] [Related]

  • 11. Biotransformation of zearalenone and zearalenols to their major glucuronide metabolites reduces estrogenic activity.
    Frizzell C, Uhlig S, Miles CO, Verhaegen S, Elliott CT, Eriksen GS, Sørlie M, Ropstad E, Connolly L.
    Toxicol In Vitro; 2015 Apr 15; 29(3):575-81. PubMed ID: 25645597
    [Abstract] [Full Text] [Related]

  • 12. In vitro phase I metabolism of cis-zearalenone.
    Drzymala SS, Herrmann AJ, Maul R, Pfeifer D, Garbe LA, Koch M.
    Chem Res Toxicol; 2014 Nov 17; 27(11):1972-8. PubMed ID: 25254638
    [Abstract] [Full Text] [Related]

  • 13. Aromatic hydroxylation and catechol formation: a novel metabolic pathway of the growth promotor zeranol.
    Hildebrand A, Pfeiffer E, Metzler M.
    Toxicol Lett; 2010 Feb 15; 192(3):379-86. PubMed ID: 19931366
    [Abstract] [Full Text] [Related]

  • 14. Comparative study of toxic effects of zearalenone and its two major metabolites alpha-zearalenol and beta-zearalenol on cultured human Caco-2 cells.
    Abid-Essefi S, Bouaziz C, Golli-Bennour EE, Ouanes Z, Bacha H.
    J Biochem Mol Toxicol; 2009 Feb 15; 23(4):233-43. PubMed ID: 19705349
    [Abstract] [Full Text] [Related]

  • 15. Absorption and metabolism of the mycotoxin zearalenone and the growth promotor zeranol in Caco-2 cells in vitro.
    Pfeiffer E, Kommer A, Dempe JS, Hildebrand AA, Metzler M.
    Mol Nutr Food Res; 2011 Apr 15; 55(4):560-7. PubMed ID: 21462323
    [Abstract] [Full Text] [Related]

  • 16. In vitro toxicological effects of estrogenic mycotoxins on human placental cells: structure activity relationships.
    Prouillac C, Koraichi F, Videmann B, Mazallon M, Rodriguez F, Baltas M, Lecoeur S.
    Toxicol Appl Pharmacol; 2012 Mar 15; 259(3):366-75. PubMed ID: 22310176
    [Abstract] [Full Text] [Related]

  • 17. Efficient screening of cytochrome P450 BM3 mutants for their metabolic activity and diversity toward a wide set of drug-like molecules in chemical space.
    Reinen J, van Leeuwen JS, Li Y, Sun L, Grootenhuis PD, Decker CJ, Saunders J, Vermeulen NP, Commandeur JN.
    Drug Metab Dispos; 2011 Sep 15; 39(9):1568-76. PubMed ID: 21673132
    [Abstract] [Full Text] [Related]

  • 18. Characterization of benidipine and its enantiomers' metabolism by human liver cytochrome P450 enzymes.
    Yoon YJ, Kim KB, Kim H, Seo KA, Kim HS, Cha IJ, Kim EY, Liu KH, Shin JG.
    Drug Metab Dispos; 2007 Sep 15; 35(9):1518-24. PubMed ID: 17537876
    [Abstract] [Full Text] [Related]

  • 19. In vitro and in vivo induction of chromosome aberrations by alpha- and beta-zearalenols: comparison with zearalenone.
    Ayed Y, Ayed-Boussema I, Ouanes Z, Bacha H.
    Mutat Res; 2011 Nov 27; 726(1):42-6. PubMed ID: 21889607
    [Abstract] [Full Text] [Related]

  • 20. Metabolism of Zearalenone in the Rumen of Dairy Cows with and without Application of a Zearalenone-Degrading Enzyme.
    Gruber-Dorninger C, Faas J, Doupovec B, Aleschko M, Stoiber C, Höbartner-Gußl A, Schöndorfer K, Killinger M, Zebeli Q, Schatzmayr D.
    Toxins (Basel); 2021 Jan 22; 13(2):. PubMed ID: 33499402
    [Abstract] [Full Text] [Related]

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