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Journal Abstract Search

621 related items for PubMed ID: 21098091

  • 1. Amelioration of neuropathic pain by novel transient receptor potential vanilloid 1 antagonist AS1928370 in rats without hyperthermic effect.
    Watabiki T, Kiso T, Kuramochi T, Yonezawa K, Tsuji N, Kohara A, Kakimoto S, Aoki T, Matsuoka N.
    J Pharmacol Exp Ther; 2011 Mar; 336(3):743-50. PubMed ID: 21098091
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  • 2. Antihyperalgesic effects of (R,E)-N-(2-hydroxy-2,3-dihydro-1H-inden-4-yl)-3-(2-(piperidin-1-yl)-4-(trifluoromethyl)phenyl)-acrylamide (AMG8562), a novel transient receptor potential vanilloid type 1 modulator that does not cause hyperthermia in rats.
    Lehto SG, Tamir R, Deng H, Klionsky L, Kuang R, Le A, Lee D, Louis JC, Magal E, Manning BH, Rubino J, Surapaneni S, Tamayo N, Wang T, Wang J, Wang J, Wang W, Youngblood B, Zhang M, Zhu D, Norman MH, Gavva NR.
    J Pharmacol Exp Ther; 2008 Jul; 326(1):218-29. PubMed ID: 18420600
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  • 3. Intrathecal administration of AS1928370, a transient receptor potential vanilloid 1 antagonist, attenuates mechanical allodynia in a mouse model of neuropathic pain.
    Watabiki T, Kiso T, Tsukamoto M, Aoki T, Matsuoka N.
    Biol Pharm Bull; 2011 Jul; 34(7):1105-8. PubMed ID: 21720020
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  • 7. Eriodictyol: a flavonoid antagonist of the TRPV1 receptor with antioxidant activity.
    Rossato MF, Trevisan G, Walker CI, Klafke JZ, de Oliveira AP, Villarinho JG, Zanon RB, Royes LF, Athayde ML, Gomez MV, Ferreira J.
    Biochem Pharmacol; 2011 Feb 15; 81(4):544-51. PubMed ID: 21087598
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  • 8. Repeated dosing of ABT-102, a potent and selective TRPV1 antagonist, enhances TRPV1-mediated analgesic activity in rodents, but attenuates antagonist-induced hyperthermia.
    Honore P, Chandran P, Hernandez G, Gauvin DM, Mikusa JP, Zhong C, Joshi SK, Ghilardi JR, Sevcik MA, Fryer RM, Segreti JA, Banfor PN, Marsh K, Neelands T, Bayburt E, Daanen JF, Gomtsyan A, Lee CH, Kort ME, Reilly RM, Surowy CS, Kym PR, Mantyh PW, Sullivan JP, Jarvis MF, Faltynek CR.
    Pain; 2009 Mar 15; 142(1-2):27-35. PubMed ID: 19135797
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  • 11. Involvement of an increased spinal TRPV1 sensitization through its up-regulation in mechanical allodynia of CCI rats.
    Kanai Y, Nakazato E, Fujiuchi A, Hara T, Imai A.
    Neuropharmacology; 2005 Dec 15; 49(7):977-84. PubMed ID: 15998524
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  • 13. N-(4-Tertiarybutylphenyl)-4-(3-cholorphyridin-2-yl)tetrahydropyrazine -1(2H)-carbox-amide (BCTC), a novel, orally effective vanilloid receptor 1 antagonist with analgesic properties: II. in vivo characterization in rat models of inflammatory and neuropathic pain.
    Pomonis JD, Harrison JE, Mark L, Bristol DR, Valenzano KJ, Walker K.
    J Pharmacol Exp Ther; 2003 Jul 15; 306(1):387-93. PubMed ID: 12721336
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  • 14. Mu-opioid receptor activation modulates transient receptor potential vanilloid 1 (TRPV1) currents in sensory neurons in a model of inflammatory pain.
    Endres-Becker J, Heppenstall PA, Mousa SA, Labuz D, Oksche A, Schäfer M, Stein C, Zöllner C.
    Mol Pharmacol; 2007 Jan 15; 71(1):12-8. PubMed ID: 17005903
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  • 16. Pharmacological characterization of (3S)-3-(hydroxymethyl)-4-(5-methylpyridin-2-yl)-N-[6-(2,2,2-trifluoroethoxy)pyridin-3-yl]-3,4-dihydro-2H-benzo[b][1,4]oxazine-8-carboxamide (JTS-653), a novel transient receptor potential vanilloid 1 antagonist.
    Kitagawa Y, Miyai A, Usui K, Hamada Y, Deai K, Wada M, Koga Y, Sakata M, Hayashi M, Tominaga M, Matsushita M.
    J Pharmacol Exp Ther; 2012 Aug 15; 342(2):520-8. PubMed ID: 22588258
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  • 18. Inhibition of peripheral vanilloid TRPV1 receptors reduces noxious heat-evoked responses of dorsal horn neurons in naïve, carrageenan-inflamed and neuropathic rats.
    Jhaveri MD, Elmes SJ, Kendall DA, Chapman V.
    Eur J Neurosci; 2005 Jul 15; 22(2):361-70. PubMed ID: 16045489
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  • 19. Participation of the spinal TRPV1 receptors in formalin-evoked pain transduction: a study using a selective TRPV1 antagonist, iodo-resiniferatoxin.
    Kanai Y, Hara T, Imai A.
    J Pharm Pharmacol; 2006 Apr 15; 58(4):489-93. PubMed ID: 16597366
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  • 20. Design of potent, orally available antagonists of the transient receptor potential vanilloid 1. Structure-activity relationships of 2-piperazin-1-yl-1H-benzimidazoles.
    Ognyanov VI, Balan C, Bannon AW, Bo Y, Dominguez C, Fotsch C, Gore VK, Klionsky L, Ma VV, Qian YX, Tamir R, Wang X, Xi N, Xu S, Zhu D, Gavva NR, Treanor JJ, Norman MH.
    J Med Chem; 2006 Jun 15; 49(12):3719-42. PubMed ID: 16759115
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