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Journal Abstract Search

126 related items for PubMed ID: 21112130

  • 1. Domino approach to 2-aroyltrimethoxyindoles as novel heterocyclic combretastatin A4 analogues.
    Arthuis M, Pontikis R, Chabot GG, Quentin L, Scherman D, Florent JC.
    Eur J Med Chem; 2011 Jan; 46(1):95-100. PubMed ID: 21112130
    [Abstract] [Full Text] [Related]

  • 2. Synthesis and structure-activity relationships of constrained heterocyclic analogues of combretastatin A4.
    Arthuis M, Pontikis R, Chabot GG, Seguin J, Quentin L, Bourg S, Morin-Allory L, Florent JC.
    ChemMedChem; 2011 Sep 05; 6(9):1693-705. PubMed ID: 21732536
    [Abstract] [Full Text] [Related]

  • 3. Structure-activity relationships of indole compounds derived from combretastatin A4: synthesis and biological screening of 5-phenylpyrrolo[3,4-a]carbazole-1,3-diones as potential antivascular agents.
    Ty N, Dupeyre G, Chabot GG, Seguin J, Quentin L, Chiaroni A, Tillequin F, Scherman D, Michel S, Cachet X.
    Eur J Med Chem; 2010 Sep 05; 45(9):3726-39. PubMed ID: 20538383
    [Abstract] [Full Text] [Related]

  • 4. 1,5-Disubstituted 1,2,3-triazoles as cis-restricted analogues of combretastatin A-4: Synthesis, molecular modeling and evaluation as cytotoxic agents and inhibitors of tubulin.
    Odlo K, Hentzen J, dit Chabert JF, Ducki S, Gani OA, Sylte I, Skrede M, Flørenes VA, Hansen TV.
    Bioorg Med Chem; 2008 May 01; 16(9):4829-38. PubMed ID: 18396050
    [Abstract] [Full Text] [Related]

  • 5. Synthesis and biological evaluation of novel heterocyclic derivatives of combretastatin A-4.
    Nguyen TT, Lomberget T, Tran NC, Colomb E, Nachtergaele L, Thoret S, Dubois J, Guillaume J, Abdayem R, Haftek M, Barret R.
    Bioorg Med Chem Lett; 2012 Dec 01; 22(23):7227-31. PubMed ID: 23063401
    [Abstract] [Full Text] [Related]

  • 6. Concise synthesis and structure-activity relationships of combretastatin A-4 analogues, 1-aroylindoles and 3-aroylindoles, as novel classes of potent antitubulin agents.
    Liou JP, Chang YL, Kuo FM, Chang CW, Tseng HY, Wang CC, Yang YN, Chang JY, Lee SJ, Hsieh HP.
    J Med Chem; 2004 Aug 12; 47(17):4247-57. PubMed ID: 15293996
    [Abstract] [Full Text] [Related]

  • 7. Synthesis and biological activity of 6H-isoindolo[2,1-a]indol-6-ones, analogues of batracylin, and related compounds.
    Guillaumel J, Léonce S, Pierré A, Renard P, Pfeiffer B, Arimondo PB, Monneret C.
    Eur J Med Chem; 2006 Mar 12; 41(3):379-86. PubMed ID: 16442188
    [Abstract] [Full Text] [Related]

  • 8. In vitro and in vivo biological evaluation of new 4,5-disubstituted 1,2,3-triazoles as cis-constrained analogs of combretastatin A4.
    Mur Blanch N, Chabot GG, Quentin L, Scherman D, Bourg S, Dauzonne D.
    Eur J Med Chem; 2012 Aug 12; 54():22-32. PubMed ID: 22647220
    [Abstract] [Full Text] [Related]

  • 9. Imidazolone-amide bridges and their effects on tubulin polymerization in cis-locked vinylogous combretastatin-A4 analogues: synthesis and biological evaluation.
    Li YW, Liu J, Liu N, Shi D, Zhou XT, Lv JG, Zhu J, Zheng CH, Zhou YJ.
    Bioorg Med Chem; 2011 Jun 01; 19(11):3579-84. PubMed ID: 21536450
    [Abstract] [Full Text] [Related]

  • 10. Isoxazole-type derivatives related to combretastatin A-4, synthesis and biological evaluation.
    Kaffy J, Pontikis R, Carrez D, Croisy A, Monneret C, Florent JC.
    Bioorg Med Chem; 2006 Jun 15; 14(12):4067-77. PubMed ID: 16510288
    [Abstract] [Full Text] [Related]

  • 11. Lead identification of conformationally restricted β-lactam type combretastatin analogues: synthesis, antiproliferative activity and tubulin targeting effects.
    Carr M, Greene LM, Knox AJ, Lloyd DG, Zisterer DM, Meegan MJ.
    Eur J Med Chem; 2010 Dec 15; 45(12):5752-66. PubMed ID: 20933304
    [Abstract] [Full Text] [Related]

  • 12. Exploring the effect of 2,3,4-trimethoxy-phenyl moiety as a component of indolephenstatins.
    Alvarez C, Alvarez R, Corchete P, Pérez-Melero C, Peláez R, Medarde M.
    Eur J Med Chem; 2010 Feb 15; 45(2):588-97. PubMed ID: 19939521
    [Abstract] [Full Text] [Related]

  • 13. Further naphthylcombretastatins. An investigation on the role of the naphthalene moiety.
    Maya AB, Pérez-Melero C, Mateo C, Alonso D, Fernández JL, Gajate C, Mollinedo F, Peláez R, Caballero E, Medarde M.
    J Med Chem; 2005 Jan 27; 48(2):556-68. PubMed ID: 15658869
    [Abstract] [Full Text] [Related]

  • 14. 2-amino and 2'-aminocombretastatin derivatives as potent antimitotic agents.
    Chang JY, Yang MF, Chang CY, Chen CM, Kuo CC, Liou JP.
    J Med Chem; 2006 Oct 19; 49(21):6412-5. PubMed ID: 17034147
    [Abstract] [Full Text] [Related]

  • 15. Examination of the 1,4-disubstituted azetidinone ring system as a template for combretastatin A-4 conformationally restricted analogue design.
    Sun L, Vasilevich NI, Fuselier JA, Hocart SJ, Coy DH.
    Bioorg Med Chem Lett; 2004 May 03; 14(9):2041-6. PubMed ID: 15080975
    [Abstract] [Full Text] [Related]

  • 16. Antineoplastic agents. 445. Synthesis and evaluation of structural modifications of (Z)- and (E)-combretastatin A-41.
    Pettit GR, Rhodes MR, Herald DL, Hamel E, Schmidt JM, Pettit RK.
    J Med Chem; 2005 Jun 16; 48(12):4087-99. PubMed ID: 15943482
    [Abstract] [Full Text] [Related]

  • 17. Synthesis and biological evaluation of vinylogous combretastatin A-4 derivatives.
    Kaffy J, Pontikis R, Florent JC, Monneret C.
    Org Biomol Chem; 2005 Jul 21; 3(14):2657-60. PubMed ID: 15999202
    [Abstract] [Full Text] [Related]

  • 18. The concise synthesis of chalcone, indanone and indenone analogues of combretastatin A4.
    Kerr DJ, Hamel E, Jung MK, Flynn BL.
    Bioorg Med Chem; 2007 May 01; 15(9):3290-8. PubMed ID: 17360188
    [Abstract] [Full Text] [Related]

  • 19. Synthesis, antitubulin, and antiproliferative SAR of analogues of 2-methoxyestradiol-3,17-O,O-bis-sulfamate.
    Jourdan F, Leese MP, Dohle W, Hamel E, Ferrandis E, Newman SP, Purohit A, Reed MJ, Potter BV.
    J Med Chem; 2010 Apr 08; 53(7):2942-51. PubMed ID: 20225862
    [Abstract] [Full Text] [Related]

  • 20. Novel A-ring and B-ring modified combretastatin A-4 (CA-4) analogues endowed with interesting cytotoxic activity.
    Simoni D, Romagnoli R, Baruchello R, Rondanin R, Grisolia G, Eleopra M, Rizzi M, Tolomeo M, Giannini G, Alloatti D, Castorina M, Marcellini M, Pisano C.
    J Med Chem; 2008 Oct 09; 51(19):6211-5. PubMed ID: 18783207
    [Abstract] [Full Text] [Related]

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