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163 related items for PubMed ID: 21114967

  • 1. Long-term social isolation exacerbates the impairment of spatial working memory in APP/PS1 transgenic mice.
    Huang HJ, Liang KC, Ke HC, Chang YY, Hsieh-Li HM.
    Brain Res; 2011 Jan 31; 1371():150-60. PubMed ID: 21114967
    [Abstract] [Full Text] [Related]

  • 2. Limited impact of social isolation on Alzheimer-like symptoms in a triple transgenic mouse model.
    Pietropaolo S, Sun Y, Li R, Brana C, Feldon J, Yee BK.
    Behav Neurosci; 2009 Feb 31; 123(1):181-95. PubMed ID: 19170443
    [Abstract] [Full Text] [Related]

  • 3. Induced LC degeneration in APP/PS1 transgenic mice accelerates early cerebral amyloidosis and cognitive deficits.
    Jardanhazi-Kurutz D, Kummer MP, Terwel D, Vogel K, Dyrks T, Thiele A, Heneka MT.
    Neurochem Int; 2010 Nov 31; 57(4):375-82. PubMed ID: 20144675
    [Abstract] [Full Text] [Related]

  • 4. Presenilin 1 regulates the processing of beta-amyloid precursor protein C-terminal fragments and the generation of amyloid beta-protein in endoplasmic reticulum and Golgi.
    Xia W, Zhang J, Ostaszewski BL, Kimberly WT, Seubert P, Koo EH, Shen J, Selkoe DJ.
    Biochemistry; 1998 Nov 24; 37(47):16465-71. PubMed ID: 9843412
    [Abstract] [Full Text] [Related]

  • 5. Neuropathology of mice carrying mutant APP(swe) and/or PS1(M146L) transgenes: alterations in the p75(NTR) cholinergic basal forebrain septohippocampal pathway.
    Jaffar S, Counts SE, Ma SY, Dadko E, Gordon MN, Morgan D, Mufson EJ.
    Exp Neurol; 2001 Aug 24; 170(2):227-43. PubMed ID: 11476589
    [Abstract] [Full Text] [Related]

  • 6. Progressive age-related development of Alzheimer-like pathology in APP/PS1 mice.
    Trinchese F, Liu S, Battaglia F, Walter S, Mathews PM, Arancio O.
    Ann Neurol; 2004 Jun 24; 55(6):801-14. PubMed ID: 15174014
    [Abstract] [Full Text] [Related]

  • 7. Selective improvement of cognitive function in adult and aged APP/PS1 transgenic mice by continuous non-shock treadmill exercise.
    Ke HC, Huang HJ, Liang KC, Hsieh-Li HM.
    Brain Res; 2011 Jul 27; 1403():1-11. PubMed ID: 21689809
    [Abstract] [Full Text] [Related]

  • 8. Reelin-immunoreactivity in the hippocampal formation of 9-month-old wildtype mouse: effects of APP/PS1 genotype and ovariectomy.
    Miettinen R, Riedel A, Kalesnykas G, Kettunen HP, Puoliväli J, Soininen H, Arendt T.
    J Chem Neuroanat; 2005 Oct 27; 30(2-3):105-18. PubMed ID: 16081247
    [Abstract] [Full Text] [Related]

  • 9. Episodic-like memory deficits in the APPswe/PS1dE9 mouse model of Alzheimer's disease: relationships to beta-amyloid deposition and neurotransmitter abnormalities.
    Savonenko A, Xu GM, Melnikova T, Morton JL, Gonzales V, Wong MP, Price DL, Tang F, Markowska AL, Borchelt DR.
    Neurobiol Dis; 2005 Apr 27; 18(3):602-17. PubMed ID: 15755686
    [Abstract] [Full Text] [Related]

  • 10. Altered levels and distribution of IGF-II/M6P receptor and lysosomal enzymes in mutant APP and APP + PS1 transgenic mouse brains.
    Amritraj A, Hawkes C, Phinney AL, Mount HT, Scott CD, Westaway D, Kar S.
    Neurobiol Aging; 2009 Jan 27; 30(1):54-70. PubMed ID: 17561313
    [Abstract] [Full Text] [Related]

  • 11. Beneficial effects of quetiapine in a transgenic mouse model of Alzheimer's disease.
    He J, Luo H, Yan B, Yu Y, Wang H, Wei Z, Zhang Y, Xu H, Tempier A, Li X, Li XM.
    Neurobiol Aging; 2009 Aug 27; 30(8):1205-16. PubMed ID: 18079026
    [Abstract] [Full Text] [Related]

  • 12. Temporal memory deficits in Alzheimer's mouse models: rescue by genetic deletion of BACE1.
    Ohno M, Chang L, Tseng W, Oakley H, Citron M, Klein WL, Vassar R, Disterhoft JF.
    Eur J Neurosci; 2006 Jan 27; 23(1):251-60. PubMed ID: 16420434
    [Abstract] [Full Text] [Related]

  • 13. Hippocampal A beta 42 levels correlate with spatial memory deficit in APP and PS1 double transgenic mice.
    Puoliväli J, Wang J, Heikkinen T, Heikkilä M, Tapiola T, van Groen T, Tanila H.
    Neurobiol Dis; 2002 Apr 27; 9(3):339-47. PubMed ID: 11950278
    [Abstract] [Full Text] [Related]

  • 14. Pharmacokinetic analysis of the blood-brain barrier transport of 125I-amyloid beta protein 40 in wild-type and Alzheimer's disease transgenic mice (APP,PS1) and its implications for amyloid plaque formation.
    Kandimalla KK, Curran GL, Holasek SS, Gilles EJ, Wengenack TM, Poduslo JF.
    J Pharmacol Exp Ther; 2005 Jun 27; 313(3):1370-8. PubMed ID: 15743932
    [Abstract] [Full Text] [Related]

  • 15. Regional metabolic alteration of Alzheimer's disease in mouse brain expressing mutant human APP-PS1 by 1H HR-MAS.
    Woo DC, Lee SH, Lee DW, Kim SY, Kim GY, Rhim HS, Choi CB, Kim HY, Lee CU, Choe BY.
    Behav Brain Res; 2010 Jul 29; 211(1):125-31. PubMed ID: 20307581
    [Abstract] [Full Text] [Related]

  • 16. Deposition of mouse amyloid beta in human APP/PS1 double and single AD model transgenic mice.
    van Groen T, Kiliaan AJ, Kadish I.
    Neurobiol Dis; 2006 Sep 29; 23(3):653-62. PubMed ID: 16829076
    [Abstract] [Full Text] [Related]

  • 17. Chronic treatment with the α2-adrenoceptor antagonist fluparoxan prevents age-related deficits in spatial working memory in APP×PS1 transgenic mice without altering β-amyloid plaque load or astrocytosis.
    Scullion GA, Kendall DA, Marsden CA, Sunter D, Pardon MC.
    Neuropharmacology; 2011 Sep 29; 60(2-3):223-34. PubMed ID: 20850464
    [Abstract] [Full Text] [Related]

  • 18. Episodic memory deficits are not related to altered glutamatergic synaptic transmission and plasticity in the CA1 hippocampus of the APPswe/PS1δE9-deleted transgenic mice model of ß-amyloidosis.
    Volianskis A, Køstner R, Mølgaard M, Hass S, Jensen MS.
    Neurobiol Aging; 2010 Jul 29; 31(7):1173-87. PubMed ID: 18790549
    [Abstract] [Full Text] [Related]

  • 19. Late onset loss of hippocampal 5-HT and NE is accompanied by increases in BDNF protein expression in mice co-expressing mutant APP and PS1.
    Szapacs ME, Numis AL, Andrews AM.
    Neurobiol Dis; 2004 Aug 29; 16(3):572-80. PubMed ID: 15262269
    [Abstract] [Full Text] [Related]

  • 20. Sensorimotor gating and memory deficits in an APP/PS1 double transgenic mouse model of Alzheimer's disease.
    Wang H, He J, Zhang R, Zhu S, Wang J, Kong L, Tan Q, Li XM.
    Behav Brain Res; 2012 Jul 15; 233(1):237-43. PubMed ID: 22595040
    [Abstract] [Full Text] [Related]


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