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201 related items for PubMed ID: 21121651

  • 1. Intestinal metabolite compound K of ginseng saponin potently attenuates metastatic growth of hepatocellular carcinoma by augmenting apoptosis via a Bid-mediated mitochondrial pathway.
    Song G, Guo S, Wang W, Hu C, Mao Y, Zhang B, Zhang H, Hu T.
    J Agric Food Chem; 2010 Dec 22; 58(24):12753-60. PubMed ID: 21121651
    [Abstract] [Full Text] [Related]

  • 2. A ginseng saponin metabolite-induced apoptosis in HepG2 cells involves a mitochondria-mediated pathway and its downstream caspase-8 activation and Bid cleavage.
    Oh SH, Lee BH.
    Toxicol Appl Pharmacol; 2004 Feb 01; 194(3):221-9. PubMed ID: 14761678
    [Abstract] [Full Text] [Related]

  • 3. Ginsenoside compound K attenuates metastatic growth of hepatocellular carcinoma, which is associated with the translocation of nuclear factor-κB p65 and reduction of matrix metalloproteinase-2/9.
    Ming Y, Chen Z, Chen L, Lin D, Tong Q, Zheng Z, Song G.
    Planta Med; 2011 Mar 01; 77(5):428-33. PubMed ID: 20979019
    [Abstract] [Full Text] [Related]

  • 4. Bid sensitizes apoptosis induced by chemotherapeutic drugs in hepatocellular carcinoma.
    Miao J, Chen GG, Chun SY, Chak EC, Lai PB.
    Int J Oncol; 2004 Sep 01; 25(3):651-9. PubMed ID: 15289866
    [Abstract] [Full Text] [Related]

  • 5. Effects of antioxidants and caspase-3 inhibitor on the phenylethyl isothiocyanate-induced apoptotic signaling pathways in human PLC/PRF/5 cells.
    Wu SJ, Ng LT, Lin CC.
    Eur J Pharmacol; 2005 Aug 22; 518(2-3):96-106. PubMed ID: 16054126
    [Abstract] [Full Text] [Related]

  • 6. Combination of interferon-α and 5-fluorouracil induces apoptosis through mitochondrial pathway in hepatocellular carcinoma in vitro.
    Yin H, Xie F, Zhang J, Yang Y, Deng B, Sun J, Wang Q, Qu X, Mao H.
    Cancer Lett; 2011 Jul 01; 306(1):34-42. PubMed ID: 21474236
    [Abstract] [Full Text] [Related]

  • 7. Induction of apoptosis by chelerythrine chloride through mitochondrial pathway and Bcl-2 family proteins in human hepatoma SMMC-7721 cell.
    Zhang ZF, Guo Y, Zhang JB, Wei XH.
    Arch Pharm Res; 2011 May 01; 34(5):791-800. PubMed ID: 21656365
    [Abstract] [Full Text] [Related]

  • 8. Genistein sensitizes human hepatocellular carcinoma cells to TRAIL-mediated apoptosis by enhancing Bid cleavage.
    Jin CY, Park C, Moon SK, Kim GY, Kwon TK, Lee SJ, Kim WJ, Choi YH.
    Anticancer Drugs; 2009 Sep 01; 20(8):713-22. PubMed ID: 19617819
    [Abstract] [Full Text] [Related]

  • 9. Bid integrates intrinsic and extrinsic signaling in apoptosis induced by alpha-tocopheryl succinate in human gastric carcinoma cells.
    Zhao Y, Li R, Xia W, Neuzil J, Lu Y, Zhang H, Zhao X, Zhang X, Sun C, Wu K.
    Cancer Lett; 2010 Feb 01; 288(1):42-9. PubMed ID: 19640637
    [Abstract] [Full Text] [Related]

  • 10. Synthetic retinoid CD437 induces mitochondria-mediated apoptosis in hepatocellular carcinoma cells.
    Gonda K, Tsuchiya H, Sakabe T, Akechi Y, Ikeda R, Nishio R, Terabayashi K, Ishii K, Matsumi Y, Ashla AA, Okamoto H, Takubo K, Matsuoka S, Watanabe Y, Hoshikawa Y, Kurimasa A, Shiota G.
    Biochem Biophys Res Commun; 2008 Jun 13; 370(4):629-33. PubMed ID: 18406343
    [Abstract] [Full Text] [Related]

  • 11. Fluvastatin, a lipophilic statin, induces apoptosis in human hepatocellular carcinoma cells through mitochondria-operated pathway.
    Zhang W, Wu J, Zhou L, Xie HY, Zheng SS.
    Indian J Exp Biol; 2010 Dec 13; 48(12):1167-74. PubMed ID: 21250597
    [Abstract] [Full Text] [Related]

  • 12. DHF-18, a new synthetic flavonoid, induced a mitochondrial-mediated apoptosis of hepatocarcinoma cells in vivo and in vitro.
    Zhang LB, Qiang L, Chen FH, Wu T, Rong JJ, Zhao Q, Zou MJ, Yang Z, You QD, Li ZY, Wu YL, Guo QL.
    Eur J Pharmacol; 2011 Jan 25; 651(1-3):33-40. PubMed ID: 21093431
    [Abstract] [Full Text] [Related]

  • 13. Cadmium induces apoptotic cell death in WI 38 cells via caspase-dependent Bid cleavage and calpain-mediated mitochondrial Bax cleavage by Bcl-2-independent pathway.
    Oh SH, Lee BH, Lim SC.
    Biochem Pharmacol; 2004 Nov 01; 68(9):1845-55. PubMed ID: 15450950
    [Abstract] [Full Text] [Related]

  • 14. Synergistic induction of TRAIL-mediated apoptosis by anisomycin in human hepatoma cells via the BH3-only protein Bid and c-Jun/AP-1 signaling pathway.
    Jin CY, Park C, Hong SH, Han MH, Jeong JW, Xu H, Liu H, Kim GY, Kim WJ, Yoo YH, Choi YH.
    Biomed Pharmacother; 2013 May 01; 67(4):321-8. PubMed ID: 23582782
    [Abstract] [Full Text] [Related]

  • 15. Antioxidant and apoptotic effects of korean white ginseng extracted with the same ratio of protopanaxadiol and protopanaxatriol saponins in human hepatoma HepG2 cells.
    Lee M, Sorn S, Baek S, Jang S, Kim S.
    Ann N Y Acad Sci; 2009 Aug 01; 1171():217-27. PubMed ID: 19723059
    [Abstract] [Full Text] [Related]

  • 16. Combination of Poly I:C and arsenic trioxide triggers apoptosis synergistically via activation of TLR3 and mitochondrial pathways in hepatocellular carcinoma cells.
    Shen P, Jiang T, Lu H, Han H, Luo R.
    Cell Biol Int; 2011 Aug 01; 35(8):803-10. PubMed ID: 21418039
    [Abstract] [Full Text] [Related]

  • 17. Anti-proliferation and apoptosis induced by a novel intestinal metabolite of ginseng saponin in human hepatocellular carcinoma cells.
    Ming YL, Song G, Chen LH, Zheng ZZ, Chen ZY, Ouyang GL, Tong QX.
    Cell Biol Int; 2007 Oct 01; 31(10):1265-73. PubMed ID: 17587608
    [Abstract] [Full Text] [Related]

  • 18. MSFTZ, a flavanone derivative, induces human hepatoma cell apoptosis via a reactive oxygen species- and caspase-dependent mitochondrial pathway.
    Ying M, Tu C, Ying H, Hu Y, He Q, Yang B.
    J Pharmacol Exp Ther; 2008 Jun 01; 325(3):758-65. PubMed ID: 18323457
    [Abstract] [Full Text] [Related]

  • 19. Isocostunolide, a sesquiterpene lactone, induces mitochondrial membrane depolarization and caspase-dependent apoptosis in human melanoma cells.
    Chen CN, Huang HH, Wu CL, Lin CP, Hsu JT, Hsieh HP, Chuang SE, Lai GM.
    Cancer Lett; 2007 Feb 08; 246(1-2):237-52. PubMed ID: 16697106
    [Abstract] [Full Text] [Related]

  • 20. Bid exhibits S phase checkpoint activation and plays a pro-apoptotic role in response to etoposide-induced DNA damage in hepatocellular carcinoma cells.
    Song G, Chen GG, Chau DK, Miao J, Lai PB.
    Apoptosis; 2008 May 08; 13(5):693-701. PubMed ID: 18373075
    [Abstract] [Full Text] [Related]

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