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Journal Abstract Search

212 related items for PubMed ID: 21122558

  • 1. A prospective evaluation of the impact of allopurinol in pediatric and adult IBD patients with preferential metabolism of 6-mercaptopurine to 6-methylmercaptopurine.
    Gerich ME, Quiros JA, Marcin JP, Tennyson L, Henthorn M, Prindiville TP.
    J Crohns Colitis; 2010 Nov; 4(5):546-52. PubMed ID: 21122558
    [Abstract] [Full Text] [Related]

  • 2. Therapeutic drug monitoring of thiopurine metabolites in adult thiopurine tolerant IBD patients on maintenance therapy.
    Gilissen LP, Wong DR, Engels LG, Bierau J, Bakker JA, Paulussen AD, Romberg-Camps MJ, Stronkhorst A, Bus P, Bos LP, Hooymans PM, Stockbrügger RW, Neef C, Masclee AA.
    J Crohns Colitis; 2012 Jul; 6(6):698-707. PubMed ID: 22398098
    [Abstract] [Full Text] [Related]

  • 3. Effect of allopurinol on clinical outcomes in inflammatory bowel disease nonresponders to azathioprine or 6-mercaptopurine.
    Sparrow MP, Hande SA, Friedman S, Cao D, Hanauer SB.
    Clin Gastroenterol Hepatol; 2007 Feb; 5(2):209-14. PubMed ID: 17296529
    [Abstract] [Full Text] [Related]

  • 4. Split-dose administration of thiopurine drugs: a novel and effective strategy for managing preferential 6-MMP metabolism.
    Shih DQ, Nguyen M, Zheng L, Ibanez P, Mei L, Kwan LY, Bradford K, Ting C, Targan SR, Vasiliauskas EA.
    Aliment Pharmacol Ther; 2012 Sep; 36(5):449-58. PubMed ID: 22784257
    [Abstract] [Full Text] [Related]

  • 5. Intrauterine exposure and pharmacology of conventional thiopurine therapy in pregnant patients with inflammatory bowel disease.
    Jharap B, de Boer NK, Stokkers P, Hommes DW, Oldenburg B, Dijkstra G, van der Woude CJ, de Jong DJ, Mulder CJ, van Elburg RM, van Bodegraven AA, Dutch Initiative on Crohn and Colitis.
    Gut; 2014 Mar; 63(3):451-7. PubMed ID: 23424097
    [Abstract] [Full Text] [Related]

  • 6. The effect of allopurinol and low-dose thiopurine combination therapy on the activity of three pivotal thiopurine metabolizing enzymes: results from a prospective pharmacological study.
    Seinen ML, van Asseldonk DP, de Boer NK, Losekoot N, Smid K, Mulder CJ, Bouma G, Peters GJ, van Bodegraven AA.
    J Crohns Colitis; 2013 Nov; 7(10):812-9. PubMed ID: 23317929
    [Abstract] [Full Text] [Related]

  • 7. Use of allopurinol in children with acute lymphoblastic leukemia to reduce skewed thiopurine metabolism.
    Brackett J, Schafer ES, Leung DH, Bernhardt MB.
    Pediatr Blood Cancer; 2014 Jun; 61(6):1114-7. PubMed ID: 24376133
    [Abstract] [Full Text] [Related]

  • 8. Steady-state of azathioprine during initiation treatment of pediatric inflammatory bowel disease.
    Pozler O, Chládek J, Malý J, Hroch M, Dědek P, Beránek M, Krásničanová P.
    J Crohns Colitis; 2010 Dec; 4(6):623-8. PubMed ID: 21122571
    [Abstract] [Full Text] [Related]

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  • 10. High TPMT enzyme activity does not explain drug resistance due to preferential 6-methylmercaptopurine production in patients on thiopurine treatment.
    van Egmond R, Chin P, Zhang M, Sies CW, Barclay ML.
    Aliment Pharmacol Ther; 2012 May; 35(10):1181-9. PubMed ID: 22486532
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  • 12. Allopurinol might improve response to azathioprine and 6-mercaptopurine by correcting an unfavorable metabolite ratio.
    Gardiner SJ, Gearry RB, Burt MJ, Chalmers-Watson T, Chapman BA, Ross AG, Stedman CA, Huelsen A, Barclay ML.
    J Gastroenterol Hepatol; 2011 Jan; 26(1):49-54. PubMed ID: 21175793
    [Abstract] [Full Text] [Related]

  • 13. Febuxostat as a novel option to optimize thiopurines' metabolism in patients with inadequate metabolite levels.
    Doré M, Frenette AJ, Mansour AM, Troyanov Y, Bégin J.
    Ann Pharmacother; 2014 May; 48(5):648-51. PubMed ID: 24523395
    [Abstract] [Full Text] [Related]

  • 14. Thiopurine methyltransferase and 6-thioguanine nucleotide measurement: early experience of use in clinical practice.
    Gearry RB, Barclay ML, Roberts RL, Harraway J, Zhang M, Pike LS, George PM, Florkowski CM.
    Intern Med J; 2005 Oct; 35(10):580-5. PubMed ID: 16207256
    [Abstract] [Full Text] [Related]

  • 15. Relationship between azathioprine dosage and thiopurine metabolites in pediatric IBD patients: identification of covariables using multilevel analysis.
    Nguyen TV, Vu DH, Nguyen TM, Lachaux A, Boulieu R.
    Ther Drug Monit; 2013 Apr; 35(2):251-7. PubMed ID: 23503453
    [Abstract] [Full Text] [Related]

  • 16. Pharmacokinetics of 6-mercaptopurine in patients with inflammatory bowel disease: implications for therapy.
    Derijks LJ, Gilissen LP, Engels LG, Bos LP, Bus PJ, Lohman JJ, Curvers WL, Van Deventer SJ, Hommes DW, Hooymans PM.
    Ther Drug Monit; 2004 Jun; 26(3):311-8. PubMed ID: 15167634
    [Abstract] [Full Text] [Related]

  • 17. Allopurinol: a useful adjunct to thiopurine therapy for pediatric ulcerative colitis in the biologic era.
    Ihekweazu FD, Kellermayer R.
    J Pediatr Gastroenterol Nutr; 2014 Jul; 59(1):22-4. PubMed ID: 24590210
    [Abstract] [Full Text] [Related]

  • 18. The potential influence of 5-aminosalicylic acid on the induction of myelotoxicity during thiopurine therapy in inflammatory bowel disease patients.
    Gao X, Zhang FB, Ding L, Liu H, Wang XD, Chen BL, Bi HC, Xiao YL, Zhao LZ, Chen MH, Huang M, Hu PJ.
    Eur J Gastroenterol Hepatol; 2012 Aug; 24(8):958-64. PubMed ID: 22664938
    [Abstract] [Full Text] [Related]

  • 19. Thiopurine metabolite ratios for monitoring therapy in pediatric Crohn disease.
    Kopylov U, Amre D, Theoret Y, Deslandres C, Seidman EG.
    J Pediatr Gastroenterol Nutr; 2014 Oct; 59(4):511-5. PubMed ID: 24918978
    [Abstract] [Full Text] [Related]

  • 20. Determination of 6-thioguanine and 6-methylmercaptopurine metabolites in renal transplantation recipients and patients with glomerulonephritis treated with azathioprine.
    Chrzanowska M, Krzymański M.
    Ther Drug Monit; 1999 Apr; 21(2):231-7. PubMed ID: 10217345
    [Abstract] [Full Text] [Related]

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