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227 related items for PubMed ID: 21124874

  • 1. SV2 mediates entry of tetanus neurotoxin into central neurons.
    Yeh FL, Dong M, Yao J, Tepp WH, Lin G, Johnson EA, Chapman ER.
    PLoS Pathog; 2010 Nov 24; 6(11):e1001207. PubMed ID: 21124874
    [Abstract] [Full Text] [Related]

  • 2. Glycosylated SV2A and SV2B mediate the entry of botulinum neurotoxin E into neurons.
    Dong M, Liu H, Tepp WH, Johnson EA, Janz R, Chapman ER.
    Mol Biol Cell; 2008 Dec 24; 19(12):5226-37. PubMed ID: 18815274
    [Abstract] [Full Text] [Related]

  • 3. SV2 is the protein receptor for botulinum neurotoxin A.
    Dong M, Yeh F, Tepp WH, Dean C, Johnson EA, Janz R, Chapman ER.
    Science; 2006 Apr 28; 312(5773):592-6. PubMed ID: 16543415
    [Abstract] [Full Text] [Related]

  • 4. Tetanus toxin and botulinum toxin a utilize unique mechanisms to enter neurons of the central nervous system.
    Blum FC, Chen C, Kroken AR, Barbieri JT.
    Infect Immun; 2012 May 28; 80(5):1662-9. PubMed ID: 22392932
    [Abstract] [Full Text] [Related]

  • 5. Synaptic vesicle endocytosis mediates the entry of tetanus neurotoxin into hippocampal neurons.
    Matteoli M, Verderio C, Rossetto O, Iezzi N, Coco S, Schiavo G, Montecucco C.
    Proc Natl Acad Sci U S A; 1996 Nov 12; 93(23):13310-5. PubMed ID: 8917587
    [Abstract] [Full Text] [Related]

  • 6. Botulinum neurotoxin A blocks synaptic vesicle exocytosis but not endocytosis at the nerve terminal.
    Neale EA, Bowers LM, Jia M, Bateman KE, Williamson LC.
    J Cell Biol; 1999 Dec 13; 147(6):1249-60. PubMed ID: 10601338
    [Abstract] [Full Text] [Related]

  • 7. Botulinum neurotoxins C, E and F bind gangliosides via a conserved binding site prior to stimulation-dependent uptake with botulinum neurotoxin F utilising the three isoforms of SV2 as second receptor.
    Rummel A, Häfner K, Mahrhold S, Darashchonak N, Holt M, Jahn R, Beermann S, Karnath T, Bigalke H, Binz T.
    J Neurochem; 2009 Sep 13; 110(6):1942-54. PubMed ID: 19650874
    [Abstract] [Full Text] [Related]

  • 8. Altered balance between excitatory and inhibitory inputs onto CA1 pyramidal neurons from SV2A-deficient but not SV2B-deficient mice.
    Venkatesan K, Alix P, Marquet A, Doupagne M, Niespodziany I, Rogister B, Seutin V.
    J Neurosci Res; 2012 Dec 13; 90(12):2317-27. PubMed ID: 22847229
    [Abstract] [Full Text] [Related]

  • 9. Botulinum neurotoxin D uses synaptic vesicle protein SV2 and gangliosides as receptors.
    Peng L, Tepp WH, Johnson EA, Dong M.
    PLoS Pathog; 2011 Mar 13; 7(3):e1002008. PubMed ID: 21483489
    [Abstract] [Full Text] [Related]

  • 10. Clostridial neurotoxins and substrate proteolysis in intact neurons: botulinum neurotoxin C acts on synaptosomal-associated protein of 25 kDa.
    Williamson LC, Halpern JL, Montecucco C, Brown JE, Neale EA.
    J Biol Chem; 1996 Mar 29; 271(13):7694-9. PubMed ID: 8631808
    [Abstract] [Full Text] [Related]

  • 11. Differential expression of synaptic vesicle protein 2 (SV2) isoforms.
    Bajjalieh SM, Frantz GD, Weimann JM, McConnell SK, Scheller RH.
    J Neurosci; 1994 Sep 29; 14(9):5223-35. PubMed ID: 8083732
    [Abstract] [Full Text] [Related]

  • 12. Tetanus toxin blocks the exocytosis of synaptic vesicles clustered at synapses but not of synaptic vesicles in isolated axons.
    Verderio C, Coco S, Bacci A, Rossetto O, De Camilli P, Montecucco C, Matteoli M.
    J Neurosci; 1999 Aug 15; 19(16):6723-32. PubMed ID: 10436029
    [Abstract] [Full Text] [Related]

  • 13. SV2 regulates neurotransmitter release via multiple mechanisms.
    Nowack A, Yao J, Custer KL, Bajjalieh SM.
    Am J Physiol Cell Physiol; 2010 Nov 15; 299(5):C960-7. PubMed ID: 20702688
    [Abstract] [Full Text] [Related]

  • 14. SV2B regulates synaptotagmin 1 by direct interaction.
    Lazzell DR, Belizaire R, Thakur P, Sherry DM, Janz R.
    J Biol Chem; 2004 Dec 10; 279(50):52124-31. PubMed ID: 15466855
    [Abstract] [Full Text] [Related]

  • 15. Double receptor anchorage of botulinum neurotoxins accounts for their exquisite neurospecificity.
    Rummel A.
    Curr Top Microbiol Immunol; 2013 Dec 10; 364():61-90. PubMed ID: 23239349
    [Abstract] [Full Text] [Related]

  • 16. Exchanging the minimal cell binding fragments of tetanus neurotoxin in botulinum neurotoxin A and B impacts their toxicity at the neuromuscular junction and central neurons.
    Höltje M, Schulze S, Strotmeier J, Mahrhold S, Richter K, Binz T, Bigalke H, Ahnert-Hilger G, Rummel A.
    Toxicon; 2013 Dec 01; 75():108-21. PubMed ID: 23817019
    [Abstract] [Full Text] [Related]

  • 17. SV2 renders primed synaptic vesicles competent for Ca2+ -induced exocytosis.
    Chang WP, Südhof TC.
    J Neurosci; 2009 Jan 28; 29(4):883-97. PubMed ID: 19176798
    [Abstract] [Full Text] [Related]

  • 18. Tetanus toxin as a neurobiological tool to study mechanisms of neuronal cell death in the mammalian brain.
    Bagetta G, Nisticò G.
    Pharmacol Ther; 1994 Jan 28; 62(1-2):29-39. PubMed ID: 7991646
    [Abstract] [Full Text] [Related]

  • 19. SV2B defines a subpopulation of synaptic vesicles.
    Paulussen I, Beckert H, Musial TF, Gschossmann LJ, Wolf J, Schmitt M, Clasadonte J, Mairet-Coello G, Wolff C, Schoch S, Dietrich D.
    J Mol Cell Biol; 2024 Apr 04; 15(9):. PubMed ID: 37682518
    [Abstract] [Full Text] [Related]

  • 20. Glycosylation is dispensable for sorting of synaptotagmin 1 but is critical for targeting of SV2 and synaptophysin to recycling synaptic vesicles.
    Kwon SE, Chapman ER.
    J Biol Chem; 2012 Oct 12; 287(42):35658-35668. PubMed ID: 22908222
    [Abstract] [Full Text] [Related]

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