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Journal Abstract Search

224 related items for PubMed ID: 21124990

  • 1. Crystal structure and size-dependent neutralization properties of HK20, a human monoclonal antibody binding to the highly conserved heptad repeat 1 of gp41.
    Sabin C, Corti D, Buzon V, Seaman MS, Lutje Hulsik D, Hinz A, Vanzetta F, Agatic G, Silacci C, Mainetti L, Scarlatti G, Sallusto F, Weiss R, Lanzavecchia A, Weissenhorn W.
    PLoS Pathog; 2010 Nov 18; 6(11):e1001195. PubMed ID: 21124990
    [Abstract] [Full Text] [Related]

  • 2. Structural basis of HIV-1 neutralization by affinity matured Fabs directed against the internal trimeric coiled-coil of gp41.
    Gustchina E, Li M, Louis JM, Anderson DE, Lloyd J, Frisch C, Bewley CA, Gustchina A, Wlodawer A, Clore GM.
    PLoS Pathog; 2010 Nov 11; 6(11):e1001182. PubMed ID: 21085615
    [Abstract] [Full Text] [Related]

  • 3. Affinity maturation and characterization of a human monoclonal antibody against HIV-1 gp41.
    Montgomery DL, Wang YJ, Hrin R, Luftig M, Su B, Miller MD, Wang F, Haytko P, Huang L, Vitelli S, Condra J, Liu X, Hampton R, Carfi A, Pessi A, Bianchi E, Joyce J, Lloyd C, Geleziunas R, Bramhill D, King VM, Finnefrock AC, Strohl W, An Z.
    MAbs; 2009 Nov 11; 1(5):462-74. PubMed ID: 20065653
    [Abstract] [Full Text] [Related]

  • 4. Binding of HIV-1 gp41-directed neutralizing and non-neutralizing fragment antibody binding domain (Fab) and single chain variable fragment (ScFv) antibodies to the ectodomain of gp41 in the pre-hairpin and six-helix bundle conformations.
    Louis JM, Aniana A, Lohith K, Sayer JM, Roche J, Bewley CA, Clore GM.
    PLoS One; 2014 Nov 11; 9(8):e104683. PubMed ID: 25105806
    [Abstract] [Full Text] [Related]

  • 5. A Derivative of the D5 Monoclonal Antibody That Targets the gp41 N-Heptad Repeat of HIV-1 with Broad Tier-2-Neutralizing Activity.
    Rubio AA, Filsinger Interrante MV, Bell BN, Brown CL, Bruun TUJ, LaBranche CC, Montefiori DC, Kim PS.
    J Virol; 2021 Jul 12; 95(15):e0235020. PubMed ID: 33980592
    [Abstract] [Full Text] [Related]

  • 6. Stabilized trimeric peptide immunogens of the complete HIV-1 gp41 N-heptad repeat and their use as HIV-1 vaccine candidates.
    Wu C, Raheem IT, Nahas DD, Citron M, Kim PS, Montefiori DC, Ottinger EA, Hepler RW, Hrin R, Patel SB, Soisson SM, Joyce JG.
    Proc Natl Acad Sci U S A; 2024 May 28; 121(22):e2317230121. PubMed ID: 38768344
    [Abstract] [Full Text] [Related]

  • 7. Antibody elicited against the gp41 N-heptad repeat (NHR) coiled-coil can neutralize HIV-1 with modest potency but non-neutralizing antibodies also bind to NHR mimetics.
    Nelson JD, Kinkead H, Brunel FM, Leaman D, Jensen R, Louis JM, Maruyama T, Bewley CA, Bowdish K, Clore GM, Dawson PE, Frederickson S, Mage RG, Richman DD, Burton DR, Zwick MB.
    Virology; 2008 Jul 20; 377(1):170-83. PubMed ID: 18499210
    [Abstract] [Full Text] [Related]

  • 8. Structural basis for HIV-1 neutralization by a gp41 fusion intermediate-directed antibody.
    Luftig MA, Mattu M, Di Giovine P, Geleziunas R, Hrin R, Barbato G, Bianchi E, Miller MD, Pessi A, Carfí A.
    Nat Struct Mol Biol; 2006 Aug 20; 13(8):740-7. PubMed ID: 16862157
    [Abstract] [Full Text] [Related]

  • 9. Interaction of anti-HIV type 1 antibody 2F5 with phospholipid bilayers and its relevance for the mechanism of virus neutralization.
    Maeso R, Huarte N, Julien JP, Kunert R, Pai EF, Nieva JL.
    AIDS Res Hum Retroviruses; 2011 Aug 20; 27(8):863-76. PubMed ID: 21142698
    [Abstract] [Full Text] [Related]

  • 10. HIV type 1 Env precursor cleavage state affects recognition by both neutralizing and nonneutralizing gp41 antibodies.
    Chakrabarti BK, Pancera M, Phogat S, O'Dell S, McKee K, Guenaga J, Robinson J, Mascola J, Wyatt RT.
    AIDS Res Hum Retroviruses; 2011 Aug 20; 27(8):877-87. PubMed ID: 21158699
    [Abstract] [Full Text] [Related]

  • 11. Computational study of bindings of HK20 Fab and D5 Fab to HIV-1 gp41.
    Hartono YD, Lazim R, Yip YM, Zhang D.
    Bioorg Med Chem Lett; 2012 Feb 15; 22(4):1695-700. PubMed ID: 22260771
    [Abstract] [Full Text] [Related]

  • 12. Affinity maturation by targeted diversification of the CDR-H2 loop of a monoclonal Fab derived from a synthetic naïve human antibody library and directed against the internal trimeric coiled-coil of gp41 yields a set of Fabs with improved HIV-1 neutralization potency and breadth.
    Gustchina E, Louis JM, Frisch C, Ylera F, Lechner A, Bewley CA, Clore GM.
    Virology; 2009 Oct 10; 393(1):112-9. PubMed ID: 19695655
    [Abstract] [Full Text] [Related]

  • 13. Functional characterization of two scFv-Fc antibodies from an HIV controller selected on soluble HIV-1 Env complexes: a neutralizing V3- and a trimer-specific gp41 antibody.
    Trott M, Weiβ S, Antoni S, Koch J, von Briesen H, Hust M, Dietrich U.
    PLoS One; 2014 Oct 10; 9(5):e97478. PubMed ID: 24828352
    [Abstract] [Full Text] [Related]

  • 14. Mechanism of HIV-1 neutralization by antibodies targeting a membrane-proximal region of gp41.
    Chen J, Frey G, Peng H, Rits-Volloch S, Garrity J, Seaman MS, Chen B.
    J Virol; 2014 Jan 10; 88(2):1249-58. PubMed ID: 24227838
    [Abstract] [Full Text] [Related]

  • 15. Structural basis for HIV-1 neutralization by 2F5-like antibodies m66 and m66.6.
    Ofek G, Zirkle B, Yang Y, Zhu Z, McKee K, Zhang B, Chuang GY, Georgiev IS, O'Dell S, Doria-Rose N, Mascola JR, Dimitrov DS, Kwong PD.
    J Virol; 2014 Mar 10; 88(5):2426-41. PubMed ID: 24335316
    [Abstract] [Full Text] [Related]

  • 16. Monoclonal Antibody 2C6 Targets a Cross-Clade Conformational Epitope in gp41 with Highly Active Antibody-Dependent Cell Cytotoxicity.
    Sojar H, Baron S, Sullivan JT, Garrett M, van Haaren MM, Hoffman J, Overbaugh J, Doranz BJ, Hicar MD.
    J Virol; 2019 Sep 01; 93(17):. PubMed ID: 31217246
    [Abstract] [Full Text] [Related]

  • 17. Antibodies purified from sera of HIV-1-infected patients by affinity on the heptad repeat region 1/heptad repeat region 2 complex of gp41 neutralize HIV-1 primary isolates.
    Vincent N, Kone A, Chanut B, Lucht F, Genin C, Malvoisin E.
    AIDS; 2008 Oct 18; 22(16):2075-85. PubMed ID: 18832871
    [Abstract] [Full Text] [Related]

  • 18. Analysis of memory B cell responses and isolation of novel monoclonal antibodies with neutralizing breadth from HIV-1-infected individuals.
    Corti D, Langedijk JP, Hinz A, Seaman MS, Vanzetta F, Fernandez-Rodriguez BM, Silacci C, Pinna D, Jarrossay D, Balla-Jhagjhoorsingh S, Willems B, Zekveld MJ, Dreja H, O'Sullivan E, Pade C, Orkin C, Jeffs SA, Montefiori DC, Davis D, Weissenhorn W, McKnight A, Heeney JL, Sallusto F, Sattentau QJ, Weiss RA, Lanzavecchia A.
    PLoS One; 2010 Jan 20; 5(1):e8805. PubMed ID: 20098712
    [Abstract] [Full Text] [Related]

  • 19. Properties of a neutralizing antibody that recognizes a conformational form of epitope ERDRD in the gp41 C-terminal tail of human immunodeficiency virus type 1.
    Cleveland SM, Jones TD, Dimmock NJ.
    J Gen Virol; 2000 May 20; 81(Pt 5):1251-60. PubMed ID: 10769067
    [Abstract] [Full Text] [Related]

  • 20. Passively transmitted gp41 antibodies in babies born from HIV-1 subtype C-seropositive women: correlation between fine specificity and protection.
    Diomede L, Nyoka S, Pastori C, Scotti L, Zambon A, Sherman G, Gray CM, Sarzotti-Kelsoe M, Lopalco L.
    J Virol; 2012 Apr 20; 86(8):4129-38. PubMed ID: 22301151
    [Abstract] [Full Text] [Related]

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