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212 related items for PubMed ID: 21127289

  • 1. Protease-activated receptor signaling in platelets activates cytosolic phospholipase A2α differently for cyclooxygenase-1 and 12-lipoxygenase catalysis.
    Holinstat M, Boutaud O, Apopa PL, Vesci J, Bala M, Oates JA, Hamm HE.
    Arterioscler Thromb Vasc Biol; 2011 Feb; 31(2):435-42. PubMed ID: 21127289
    [Abstract] [Full Text] [Related]

  • 2. Group IVA cytosolic phospholipase A2 (cPLA2alpha) and integrin alphaIIbbeta3 reinforce each other's functions during alphaIIbbeta3 signaling in platelets.
    Prévost N, Mitsios JV, Kato H, Burke JE, Dennis EA, Shimizu T, Shattil SJ.
    Blood; 2009 Jan 08; 113(2):447-57. PubMed ID: 18840708
    [Abstract] [Full Text] [Related]

  • 3. An anti-platelet agent, OPC-29030, inhibits translocation of 12-lipoxygenase and 12-hydroxyeicosatetraenoic acid production in human platelets.
    Ozeki Y, Nagamura Y, Ito H, Unemi F, Kimura Y, Igawa T, Kambayashi Ji, Takahashi Y, Yoshimoto T.
    Br J Pharmacol; 1999 Dec 08; 128(8):1699-704. PubMed ID: 10588925
    [Abstract] [Full Text] [Related]

  • 4. Arachidonyl trifluoromethyl ketone, a potent inhibitor of 85-kDa phospholipase A2, blocks production of arachidonate and 12-hydroxyeicosatetraenoic acid by calcium ionophore-challenged platelets.
    Riendeau D, Guay J, Weech PK, Laliberté F, Yergey J, Li C, Desmarais S, Perrier H, Liu S, Nicoll-Griffith D.
    J Biol Chem; 1994 Jun 03; 269(22):15619-24. PubMed ID: 8195210
    [Abstract] [Full Text] [Related]

  • 5. Phospholipid-esterified eicosanoids are generated in agonist-activated human platelets and enhance tissue factor-dependent thrombin generation.
    Thomas CP, Morgan LT, Maskrey BH, Murphy RC, Kühn H, Hazen SL, Goodall AH, Hamali HA, Collins PW, O'Donnell VB.
    J Biol Chem; 2010 Mar 05; 285(10):6891-903. PubMed ID: 20061396
    [Abstract] [Full Text] [Related]

  • 6. Polychlorinated biphenyls induce arachidonic acid release in human platelets in a tamoxifen sensitive manner via activation of group IVA cytosolic phospholipase A2-alpha.
    Forsell PK, Olsson AO, Andersson E, Nallan L, Gelb MH.
    Biochem Pharmacol; 2005 Dec 19; 71(1-2):144-55. PubMed ID: 16290172
    [Abstract] [Full Text] [Related]

  • 7. Inherited human cPLA(2alpha) deficiency is associated with impaired eicosanoid biosynthesis, small intestinal ulceration, and platelet dysfunction.
    Adler DH, Cogan JD, Phillips JA, Schnetz-Boutaud N, Milne GL, Iverson T, Stein JA, Brenner DA, Morrow JD, Boutaud O, Oates JA.
    J Clin Invest; 2008 Jun 19; 118(6):2121-31. PubMed ID: 18451993
    [Abstract] [Full Text] [Related]

  • 8. Arachidonic acid regulation of the cytosolic phospholipase A 2α/cyclooxygenase-2 pathway in mouse endometrial stromal cells.
    Zhao ZA, Zhang ZR, Xu X, Deng WB, Li M, Leng JY, Liang XH, Yang ZM.
    Fertil Steril; 2012 May 19; 97(5):1199-205.e1-9. PubMed ID: 22369775
    [Abstract] [Full Text] [Related]

  • 9. Effect of selective inhibition of the p38 MAP kinase pathway on platelet aggregation.
    Kuliopulos A, Mohanlal R, Covic L.
    Thromb Haemost; 2004 Dec 19; 92(6):1387-93. PubMed ID: 15583748
    [Abstract] [Full Text] [Related]

  • 10. Thrombopoietin complements G(i)- but not G(q)-dependent pathways for integrin {alpha}(IIb){beta}(3) activation and platelet aggregation.
    Campus F, Lova P, Bertoni A, Sinigaglia F, Balduini C, Torti M.
    J Biol Chem; 2005 Jul 01; 280(26):24386-95. PubMed ID: 15863506
    [Abstract] [Full Text] [Related]

  • 11. p38 mitogen-activated protein kinase phosphorylates cytosolic phospholipase A2 (cPLA2) in thrombin-stimulated platelets. Evidence that proline-directed phosphorylation is not required for mobilization of arachidonic acid by cPLA2.
    Kramer RM, Roberts EF, Um SL, Börsch-Haubold AG, Watson SP, Fisher MJ, Jakubowski JA.
    J Biol Chem; 1996 Nov 01; 271(44):27723-9. PubMed ID: 8910365
    [Abstract] [Full Text] [Related]

  • 12. Evidence for a role for phospholipase C, but not phospholipase A2, in platelet activation in response to low concentrations of collagen.
    Lockhart LK, Pampolina C, Nickolaychuk BR, McNicol A.
    Thromb Haemost; 2001 May 01; 85(5):882-9. PubMed ID: 11372683
    [Abstract] [Full Text] [Related]

  • 13. Decrease in expression or activity of cytosolic phospholipase A2alpha increases cyclooxygenase-1 action: A cross-talk between key enzymes in arachidonic acid pathway in prostate cancer cells.
    Niknami M, Vignarajan S, Yao M, Hua S, Witting PK, Kita Y, Shimizu T, Sved P, Patel MI, Dong Q.
    Biochim Biophys Acta; 2010 Jul 01; 1801(7):731-7. PubMed ID: 20227521
    [Abstract] [Full Text] [Related]

  • 14. Lipid Receptor GPR31 (G-Protein-Coupled Receptor 31) Regulates Platelet Reactivity and Thrombosis Without Affecting Hemostasis.
    Van Doren L, Nguyen N, Garzia C, Fletcher EK, Stevenson R, Jaramillo D, Kuliopulos A, Covic L.
    Arterioscler Thromb Vasc Biol; 2021 Jan 01; 41(1):e33-e45. PubMed ID: 33267659
    [Abstract] [Full Text] [Related]

  • 15. Evidence that 12-lipoxygenase product 12-hydroxyeicosatetraenoic acid activates p21-activated kinase.
    Wen Y, Gu J, Knaus UG, Thomas L, Gonzales N, Nadler JL.
    Biochem J; 2000 Jul 15; 349(Pt 2):481-7. PubMed ID: 10880347
    [Abstract] [Full Text] [Related]

  • 16. Eicosanoid activation of extracellular signal-regulated kinase1/2 in human epidermoid carcinoma cells.
    Szekeres CK, Tang K, Trikha M, Honn KV.
    J Biol Chem; 2000 Dec 08; 275(49):38831-41. PubMed ID: 10952974
    [Abstract] [Full Text] [Related]

  • 17. 5-Hydroxytryptamine and the metabolism of arachidonic acid by the lipoxygenase and cyclooxygenase of washed human platelets.
    Dragan YP, Ellis EF.
    Biochem Pharmacol; 1990 Jul 15; 40(2):309-14. PubMed ID: 2142882
    [Abstract] [Full Text] [Related]

  • 18. Cytosolic phospholipase A2alpha activation induced by S1P is mediated by the S1P3 receptor in lung epithelial cells.
    Chen LY, Woszczek G, Nagineni S, Logun C, Shelhamer JH.
    Am J Physiol Lung Cell Mol Physiol; 2008 Aug 15; 295(2):L326-35. PubMed ID: 18502815
    [Abstract] [Full Text] [Related]

  • 19. 15-Lipoxygenation of leukotriene A(4). Studies Of 12- and 15-lipoxygenase efficiency to catalyze lipoxin formation.
    Tornhamre S, Elmqvist A, Lindgren JA.
    Biochim Biophys Acta; 2000 Apr 12; 1484(2-3):298-306. PubMed ID: 10760478
    [Abstract] [Full Text] [Related]

  • 20. Studies on the role of platelet eicosanoid metabolism and integrin alpha IIb beta 3 in tumor-cell-induced platelet aggregation.
    Steinert BW, Tang DG, Grossi IM, Umbarger LA, Honn KV.
    Int J Cancer; 1993 Apr 22; 54(1):92-101. PubMed ID: 8478151
    [Abstract] [Full Text] [Related]


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