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Journal Abstract Search

98 related items for PubMed ID: 21127790

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  • 2. 3'-[4-Aryl-(1,2,3-triazol-1-yl)]-3'-deoxythymidine analogues as potent and selective inhibitors of human mitochondrial thymidine kinase.
    Van Poecke S, Negri A, Gago F, Van Daele I, Solaroli N, Karlsson A, Balzarini J, Van Calenbergh S.
    J Med Chem; 2010 Apr 08; 53(7):2902-12. PubMed ID: 20218622
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  • 3. Deoxyribonucleoside kinases belonging to the thymidine kinase 2 (TK2)-like group vary significantly in substrate specificity, kinetics and feed-back regulation.
    Knecht W, Petersen GE, Munch-Petersen B, Piskur J.
    J Mol Biol; 2002 Jan 25; 315(4):529-40. PubMed ID: 11812127
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  • 5. Synthesis of 5-(carboranylalkylmercapto)-2'-deoxyuridines and 3-(carboranylalkyl)thymidines and their evaluation as substrates for human thymidine kinases 1 and 2.
    Lunato AJ, Wang J, Woollard JE, Anisuzzaman AK, Ji W, Rong FG, Ikeda S, Soloway AH, Eriksson S, Ives DH, Blue TE, Tjarks W.
    J Med Chem; 1999 Aug 26; 42(17):3378-89. PubMed ID: 10464024
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  • 7. Cloning and characterization of full-length mouse thymidine kinase 2: the N-terminal sequence directs import of the precursor protein into mitochondria.
    Wang L, Eriksson S.
    Biochem J; 2000 Oct 15; 351 Pt 2(Pt 2):469-76. PubMed ID: 11023833
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  • 9. Rational design of 5'-thiourea-substituted alpha-thymidine analogues as thymidine monophosphate kinase inhibitors capable of inhibiting mycobacterial growth.
    Van Daele I, Munier-Lehmann H, Froeyen M, Balzarini J, Van Calenbergh S.
    J Med Chem; 2007 Nov 01; 50(22):5281-92. PubMed ID: 17910427
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  • 12. Novel selective human mitochondrial kinase inhibitors: design, synthesis and enzymatic activity.
    Ciliberti N, Manfredini S, Angusti A, Durini E, Solaroli N, Vertuani S, Buzzoni L, Bonache MC, Ben-Shalom E, Karlsson A, Saada A, Balzarini J.
    Bioorg Med Chem; 2007 Apr 15; 15(8):3065-81. PubMed ID: 17324575
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  • 14. Substrate/inhibitor properties of human deoxycytidine kinase (dCK) and thymidine kinases (TK1 and TK2) towards the sugar moiety of nucleosides, including O'-alkyl analogues.
    Kierdaszuk B, Krawiec K, Kazimierczuk Z, Jacobsson U, Johansson NG, Munch-Petersen B, Eriksson S, Shugar D.
    Nucleosides Nucleotides; 1999 Aug 15; 18(8):1883-903. PubMed ID: 10478487
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  • 16. Long term expression of Drosophila melanogaster nucleoside kinase in thymidine kinase 2-deficient mice with no lethal effects caused by nucleotide pool imbalances.
    Krishnan S, Paredes JA, Zhou X, Kuiper RV, Hultenby K, Curbo S, Karlsson A.
    J Biol Chem; 2014 Nov 21; 289(47):32835-44. PubMed ID: 25296759
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  • 19. Bromovinyl-deoxyuridine: A selective substrate for mitochondrial thymidine kinase in cell extracts.
    Franzolin E, Rampazzo C, Pérez-Pérez MJ, Hernández AI, Balzarini J, Bianchi V.
    Biochem Biophys Res Commun; 2006 May 26; 344(1):30-6. PubMed ID: 16630572
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