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Journal Abstract Search

668 related items for PubMed ID: 21130095

  • 1. Solution ELISA as a platform of choice for development of robust, drug tolerant immunogenicity assays in support of drug development.
    Mikulskis A, Yeung D, Subramanyam M, Amaravadi L.
    J Immunol Methods; 2011 Feb 28; 365(1-2):38-49. PubMed ID: 21130095
    [Abstract] [Full Text] [Related]

  • 2. A novel homogeneous Biotin-digoxigenin based assay for the detection of human anti-therapeutic antibodies in autoimmune serum.
    Qiu ZJ, Ying Y, Fox M, Peng K, Lewin-Koh SC, Coleman D, Good J, Lowe J, Rahman A, Yang J, Jiang J, Quarmby V, Song A.
    J Immunol Methods; 2010 Oct 31; 362(1-2):101-11. PubMed ID: 20868690
    [Abstract] [Full Text] [Related]

  • 3. Evaluation of a generic immunoassay with drug tolerance to detect immune complexes in serum samples from cynomolgus monkeys after administration of human antibodies.
    Stubenrauch K, Wessels U, Essig U, Vogel R, Schleypen J.
    J Pharm Biomed Anal; 2010 Jun 05; 52(2):249-54. PubMed ID: 20083366
    [Abstract] [Full Text] [Related]

  • 4. Clinical immunogenicity specificity assessments: a platform evaluation.
    Peng K, Siradze K, Quarmby V, Fischer SK.
    J Pharm Biomed Anal; 2011 Feb 20; 54(3):629-35. PubMed ID: 21035975
    [Abstract] [Full Text] [Related]

  • 5. Detection of low-affinity anti-drug antibodies and improved drug tolerance in immunogenicity testing by Octet(®) biolayer interferometry.
    Li J, Schantz A, Schwegler M, Shankar G.
    J Pharm Biomed Anal; 2011 Jan 25; 54(2):286-94. PubMed ID: 20869832
    [Abstract] [Full Text] [Related]

  • 6. Strategies to estimate and improve drug tolerance in anti-drug antibody assays.
    Bütikofer L, Lemaillet G, Faust H.
    Bioanalysis; 2012 Aug 25; 4(16):1999-2012. PubMed ID: 22946916
    [Abstract] [Full Text] [Related]

  • 7. Strategic selection and development of immunogenicity binding methods.
    Menendez AT.
    Bioanalysis; 2012 Jun 25; 4(12):1491-508. PubMed ID: 22793033
    [Abstract] [Full Text] [Related]

  • 8. Improvement of drug tolerance in immunogenicity testing by acid treatment on Biacore.
    Sickert D, Kroeger K, Zickler C, Chokote E, Winkler B, Grenet JM, Legay F, Zaar A.
    J Immunol Methods; 2008 May 20; 334(1-2):29-36. PubMed ID: 18304570
    [Abstract] [Full Text] [Related]

  • 9. Detection of antibodies against therapeutic proteins in the presence of residual therapeutic protein using a solid-phase extraction with acid dissociation (SPEAD) sample treatment prior to ELISA.
    Smith HW, Butterfield A, Sun D.
    Regul Toxicol Pharmacol; 2007 Dec 20; 49(3):230-7. PubMed ID: 17869396
    [Abstract] [Full Text] [Related]

  • 10. Generic anti-drug antibody assay with drug tolerance in serum samples from mice exposed to human antibodies.
    Stubenrauch K, Mackeben K, Vogel R, Heinrich J.
    Anal Biochem; 2012 Nov 15; 430(2):193-9. PubMed ID: 22935295
    [Abstract] [Full Text] [Related]

  • 11. An Affinity Capture Elution (ACE) assay for detection of anti-drug antibody to monoclonal antibody therapeutics in the presence of high levels of drug.
    Bourdage JS, Cook CA, Farrington DL, Chain JS, Konrad RJ.
    J Immunol Methods; 2007 Oct 31; 327(1-2):10-7. PubMed ID: 17716682
    [Abstract] [Full Text] [Related]

  • 12. Evaluation of an immunoassay for human-specific quantitation of therapeutic antibodies in serum samples from non-human primates.
    Stubenrauch K, Wessels U, Lenz H.
    J Pharm Biomed Anal; 2009 May 01; 49(4):1003-8. PubMed ID: 19250787
    [Abstract] [Full Text] [Related]

  • 13. A breakthrough novel method to resolve the drug and target interference problem in immunogenicity assays.
    Zoghbi J, Xu Y, Grabert R, Theobald V, Richards S.
    J Immunol Methods; 2015 Nov 01; 426():62-9. PubMed ID: 26255760
    [Abstract] [Full Text] [Related]

  • 14. A double antigen bridging immunogenicity ELISA for the detection of antibodies to polyethylene glycol polymers.
    Liu Y, Reidler H, Pan J, Milunic D, Qin D, Chen D, Vallejo YR, Yin R.
    J Pharmacol Toxicol Methods; 2011 Nov 01; 64(3):238-45. PubMed ID: 21827863
    [Abstract] [Full Text] [Related]

  • 15. Complexities of clinical assay development and optimization prior to first-in-man immunization trials - a description of immunogenicity assay development for the testing of samples from a phase 1 Alzheimer's vaccine trial.
    Hammond O, Reynolds J, Rubinstein LJ, Sikkema D, Marchese RD.
    J Immunoassay Immunochem; 2008 Nov 01; 29(4):332-47. PubMed ID: 18821408
    [Abstract] [Full Text] [Related]

  • 16. A systematic study of the effect of low pH acid treatment on anti-drug antibodies specific for a domain antibody therapeutic: Impact on drug tolerance, assay sensitivity and post-validation method assessment of ADA in clinical serum samples.
    Kavita U, Duo J, Crawford SM, Liu R, Valcin J, Gleason C, Dong H, Gadkari S, Dodge RW, Pillutla RC, DeSilva BS.
    J Immunol Methods; 2017 Sep 01; 448():91-104. PubMed ID: 28625864
    [Abstract] [Full Text] [Related]

  • 17. Increased rheumatoid factor interference observed during immunogenicity assessment of an Fc-engineered therapeutic antibody.
    Araujo J, Zocher M, Wallace K, Peng K, Fischer SK.
    J Pharm Biomed Anal; 2011 Jul 15; 55(5):1041-9. PubMed ID: 21466939
    [Abstract] [Full Text] [Related]

  • 18. Development of a biosensor-based immunogenicity assay capable of blocking soluble drug target interference.
    Weeraratne DK, Lofgren J, Dinnogen S, Swanson SJ, Zhong ZD.
    J Immunol Methods; 2013 Oct 31; 396(1-2):44-55. PubMed ID: 23933325
    [Abstract] [Full Text] [Related]

  • 19. Bioanalytical platform comparison using a generic human IgG PK assay format.
    Leary BA, Lawrence-Henderson R, Mallozzi C, Fernandez Ocaña M, Duriga N, O'Hara DM, Kavosi M, Qu Q, Joyce AP.
    J Immunol Methods; 2013 Nov 29; 397(1-2):28-36. PubMed ID: 23994108
    [Abstract] [Full Text] [Related]

  • 20. Overcoming soluble target interference in an anti-therapeutic antibody screening assay for an antibody-drug conjugate therapeutic.
    Carrasco-Triguero M, Mahood C, Milojic-Blair M, Amaya C, Ruppel J, Hong K, Yi JH, Kaur S.
    Bioanalysis; 2012 Aug 29; 4(16):2013-26. PubMed ID: 22946917
    [Abstract] [Full Text] [Related]

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