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Journal Abstract Search

244 related items for PubMed ID: 21131602

  • 1. Pulmonary fibrosis inducer, bleomycin, causes redox-sensitive activation of phospholipase D and cytotoxicity through formation of bioactive lipid signal mediator, phosphatidic acid, in lung microvascular endothelial cells.
    Patel RB, Kotha SR, Sherwani SI, Sliman SM, Gurney TO, Loar B, Butler SO, Morris AJ, Marsh CB, Parinandi NL.
    Int J Toxicol; 2011 Feb; 30(1):69-90. PubMed ID: 21131602
    [Abstract] [Full Text] [Related]

  • 2. Novel lipid-soluble thiol-redox antioxidant and heavy metal chelator, N,N'-bis(2-mercaptoethyl)isophthalamide (NBMI) and phospholipase D-specific inhibitor, 5-fluoro-2-indolyl des-chlorohalopemide (FIPI) attenuate mercury-induced lipid signaling leading to protection against cytotoxicity in aortic endothelial cells.
    Secor JD, Kotha SR, Gurney TO, Patel RB, Kefauver NR, Gupta N, Morris AJ, Haley BE, Parinandi NL.
    Int J Toxicol; 2011 Dec; 30(6):619-38. PubMed ID: 21994240
    [Abstract] [Full Text] [Related]

  • 3. Thiol-redox antioxidants protect against lung vascular endothelial cytoskeletal alterations caused by pulmonary fibrosis inducer, bleomycin: comparison between classical thiol-protectant, N-acetyl-L-cysteine, and novel thiol antioxidant, N,N'-bis-2-mercaptoethyl isophthalamide.
    Patel RB, Kotha SR, Sauers LA, Malireddy S, Gurney TO, Gupta NN, Elton TS, Magalang UJ, Marsh CB, Haley BE, Parinandi NL.
    Toxicol Mech Methods; 2012 Jun; 22(5):383-96. PubMed ID: 22409285
    [Abstract] [Full Text] [Related]

  • 4. Classic Phytochemical Antioxidant and Lipoxygenase Inhibitor, Nordihydroguaiaretic Acid, Activates Phospholipase D through Oxidant Signaling and Tyrosine Phosphorylation Leading to Cytotoxicity in Lung Vascular Endothelial Cells.
    Parinandi NL, Liaugminas A, Oliver PJ, Varadharaj S, Yenigalla A, Elliott AC, Arutla S, Campbell SJ, Kotha SR, Sherwani SI, Kutala VK, McDaniel JC, Maddipati KR, Kuppusamy P, Hund TJ.
    Cell Biochem Biophys; 2023 Jun; 81(2):205-229. PubMed ID: 36820994
    [Abstract] [Full Text] [Related]

  • 5. Hyperoxia alters phorbol ester-induced phospholipase D activation in bovine lung microvascular endothelial cells.
    Roy S, Parinandi N, Zeigelstein R, Hu Q, Pei Y, Travers JB, Natarajan V.
    Antioxid Redox Signal; 2003 Apr; 5(2):217-28. PubMed ID: 12716481
    [Abstract] [Full Text] [Related]

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  • 7. Redox-active antioxidant modulation of lipid signaling in vascular endothelial cells: vitamin C induces activation of phospholipase D through phospholipase A2, lipoxygenase, and cyclooxygenase.
    Steinhour E, Sherwani SI, Mazerik JN, Ciapala V, O'Connor Butler E, Cruff JP, Magalang U, Parthasarathy S, Sen CK, Marsh CB, Kuppusamy P, Parinandi NL.
    Mol Cell Biochem; 2008 Aug; 315(1-2):97-112. PubMed ID: 18496733
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  • 9. The phospholipase D inhibitor FIPI potently blocks EGF-induced calcium signaling in human breast cancer cells.
    Stricker HM, Rommerswinkel N, Keil S, Gnoth SA, Niggemann B, Dittmar T.
    Cell Commun Signal; 2021 Apr 08; 19(1):43. PubMed ID: 33832505
    [Abstract] [Full Text] [Related]

  • 10. Phospholipase D activation in endothelial cells is redox sensitive.
    Parinandi NL, Scribner WM, Vepa S, Shi S, Natarajan V.
    Antioxid Redox Signal; 1999 Apr 08; 1(2):193-210. PubMed ID: 11228747
    [Abstract] [Full Text] [Related]

  • 11. A novel role for phospholipase D as an endogenous negative regulator of platelet sensitivity.
    Elvers M, Grenegård M, Khoshjabinzadeh H, Münzer P, Borst O, Tian H, Di Paolo G, Lang F, Gawaz M, Lindahl TL, Fälker K.
    Cell Signal; 2012 Sep 08; 24(9):1743-52. PubMed ID: 22579635
    [Abstract] [Full Text] [Related]

  • 12. Vitamin C-induced activation of phospholipase D in lung microvascular endothelial cells: regulation by MAP kinases.
    Varadharaj S, Steinhour E, Hunter MG, Watkins T, Baran CP, Magalang U, Kuppusamy P, Zweier JL, Marsh CB, Natarajan V, Parinandi NL.
    Cell Signal; 2006 Sep 08; 18(9):1396-407. PubMed ID: 16376521
    [Abstract] [Full Text] [Related]

  • 13. 4-Hydroxynonenal, a metabolite of lipid peroxidation, activates phospholipase D in vascular endothelial cells.
    Natarajan V, Scribner WM, Taher MM.
    Free Radic Biol Med; 1993 Oct 08; 15(4):365-75. PubMed ID: 8225018
    [Abstract] [Full Text] [Related]

  • 14. Phospholipase D/phosphatidic acid signal transduction: role and physiological significance in lung.
    Cummings R, Parinandi N, Wang L, Usatyuk P, Natarajan V.
    Mol Cell Biochem; 2002 Oct 08; 234-235(1-2):99-109. PubMed ID: 12162465
    [Abstract] [Full Text] [Related]

  • 15. Oxidant stress enhances Lyso-PAF-AcT activity by modifying phospholipase D and phosphatidic acid in aortic endothelial cells.
    Corl CM, Cao YZ, Cohen ZS, Sordillo LM.
    Biochem Biophys Res Commun; 2003 Mar 14; 302(3):610-4. PubMed ID: 12615078
    [Abstract] [Full Text] [Related]

  • 16. Reversible bleb formation in mast cells stimulated with antigen is Ca2+/calmodulin-dependent and bleb size is regulated by ARF6.
    Yanase Y, Carvou N, Frohman MA, Cockcroft S.
    Biochem J; 2009 Dec 14; 425(1):179-93. PubMed ID: 19845506
    [Abstract] [Full Text] [Related]

  • 17. Mercury activates vascular endothelial cell phospholipase D through thiols and oxidative stress.
    Hagele TJ, Mazerik JN, Gregory A, Kaufman B, Magalang U, Kuppusamy ML, Marsh CB, Kuppusamy P, Parinandi NL.
    Int J Toxicol; 2007 Dec 14; 26(1):57-69. PubMed ID: 17365148
    [Abstract] [Full Text] [Related]

  • 18. Activation of endothelial cell phospholipase D by sphingosine and sphingosine-1-phosphate.
    Natarajan V, Jayaram HN, Scribner WM, Garcia JG.
    Am J Respir Cell Mol Biol; 1994 Aug 14; 11(2):221-9. PubMed ID: 8049083
    [Abstract] [Full Text] [Related]

  • 19. Pharmacological inhibition of phospholipase D protects mice from occlusive thrombus formation and ischemic stroke--brief report.
    Stegner D, Thielmann I, Kraft P, Frohman MA, Stoll G, Nieswandt B.
    Arterioscler Thromb Vasc Biol; 2013 Sep 14; 33(9):2212-7. PubMed ID: 23868933
    [Abstract] [Full Text] [Related]

  • 20. Oxidized low density lipoprotein-mediated activation of phospholipase D in smooth muscle cells: a possible role in cell proliferation and atherogenesis.
    Natarajan V, Scribner WM, Hart CM, Parthasarathy S.
    J Lipid Res; 1995 Sep 14; 36(9):2005-16. PubMed ID: 8558088
    [Abstract] [Full Text] [Related]

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