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Journal Abstract Search

191 related items for PubMed ID: 21148249

  • 1. ELR510444, a novel microtubule disruptor with multiple mechanisms of action.
    Risinger AL, Westbrook CD, Encinas A, Mülbaier M, Schultes CM, Wawro S, Lewis JD, Janssen B, Giles FJ, Mooberry SL.
    J Pharmacol Exp Ther; 2011 Mar; 336(3):652-60. PubMed ID: 21148249
    [Abstract] [Full Text] [Related]

  • 2. ELR510444 inhibits tumor growth and angiogenesis by abrogating HIF activity and disrupting microtubules in renal cell carcinoma.
    Carew JS, Esquivel JA, Espitia CM, Schultes CM, Mülbaier M, Lewis JD, Janssen B, Giles FJ, Nawrocki ST.
    PLoS One; 2012 Mar; 7(1):e31120. PubMed ID: 22295124
    [Abstract] [Full Text] [Related]

  • 3. 2-Alkoxycarbonyl-3-arylamino-5-substituted thiophenes as a novel class of antimicrotubule agents: Design, synthesis, cell growth and tubulin polymerization inhibition.
    Romagnoli R, Kimatrai Salvador M, Schiaffino Ortega S, Baraldi PG, Oliva P, Baraldi S, Lopez-Cara LC, Brancale A, Ferla S, Hamel E, Balzarini J, Liekens S, Mattiuzzo E, Basso G, Viola G.
    Eur J Med Chem; 2018 Jan 01; 143():683-698. PubMed ID: 29220790
    [Abstract] [Full Text] [Related]

  • 4. NMK-TD-100, a novel microtubule modulating agent, blocks mitosis and induces apoptosis in HeLa cells by binding to tubulin.
    Bhattacharya S, Kumar NM, Ganguli A, Tantak MP, Kumar D, Chakrabarti G.
    PLoS One; 2013 Jan 01; 8(10):e76286. PubMed ID: 24116100
    [Abstract] [Full Text] [Related]

  • 5. 2-Methoxyestradiol suppresses microtubule dynamics and arrests mitosis without depolymerizing microtubules.
    Kamath K, Okouneva T, Larson G, Panda D, Wilson L, Jordan MA.
    Mol Cancer Ther; 2006 Sep 01; 5(9):2225-33. PubMed ID: 16985056
    [Abstract] [Full Text] [Related]

  • 6. Microtubule dynamics, mitotic arrest, and apoptosis: drug-induced differential effects of betaIII-tubulin.
    Gan PP, McCarroll JA, Po'uha ST, Kamath K, Jordan MA, Kavallaris M.
    Mol Cancer Ther; 2010 May 01; 9(5):1339-48. PubMed ID: 20442307
    [Abstract] [Full Text] [Related]

  • 7. 6α-Acetoxyanopterine: A Novel Structure Class of Mitotic Inhibitor Disrupting Microtubule Dynamics in Prostate Cancer Cells.
    Levrier C, Sadowski MC, Rockstroh A, Gabrielli B, Kavallaris M, Lehman M, Davis RA, Nelson CC.
    Mol Cancer Ther; 2017 Jan 01; 16(1):3-15. PubMed ID: 27760837
    [Abstract] [Full Text] [Related]

  • 8. A novel sulfonamide agent, MPSP-001, exhibits potent activity against human cancer cells in vitro through disruption of microtubule.
    Liu ZL, Tian W, Wang Y, Kuang S, Luo XM, Yu Q.
    Acta Pharmacol Sin; 2012 Feb 01; 33(2):261-70. PubMed ID: 22301862
    [Abstract] [Full Text] [Related]

  • 9. Selective Inhibition of Spindle Microtubules by a Tubulin-Binding Quinazoline Derivative.
    Sawada JI, Ishii H, Matsuno K, Sato M, Suzuki Y, Asai A.
    Mol Pharmacol; 2019 Nov 01; 96(5):609-618. PubMed ID: 31471455
    [Abstract] [Full Text] [Related]

  • 10. CKT0353, a novel microtubule targeting agent, overcomes paclitaxel induced resistance in cancer cells.
    Dinić J, Ríos-Luci C, Karpaviciene I, Cikotiene I, Fernandes MX, Pešić M, Padrón JM.
    Invest New Drugs; 2020 Jun 01; 38(3):584-598. PubMed ID: 31177401
    [Abstract] [Full Text] [Related]

  • 11. An antitubulin agent BCFMT inhibits proliferation of cancer cells and induces cell death by inhibiting microtubule dynamics.
    Rai A, Surolia A, Panda D.
    PLoS One; 2012 Jun 01; 7(8):e44311. PubMed ID: 22952952
    [Abstract] [Full Text] [Related]

  • 12. Microtubule Destabilizing Sulfonamides as an Alternative to Taxane-Based Chemotherapy.
    González M, Ovejero-Sánchez M, Vicente-Blázquez A, Álvarez R, Herrero AB, Medarde M, González-Sarmiento R, Peláez R.
    Int J Mol Sci; 2021 Feb 14; 22(4):. PubMed ID: 33673002
    [Abstract] [Full Text] [Related]

  • 13. A novel bis-indole destabilizes microtubules and displays potent in vitro and in vivo antitumor activity in prostate cancer.
    Ahn S, Hwang DJ, Barrett CM, Yang J, Duke CB, Miller DD, Dalton JT.
    Cancer Chemother Pharmacol; 2011 Feb 14; 67(2):293-304. PubMed ID: 20383708
    [Abstract] [Full Text] [Related]

  • 14. Taccalonolide binding to tubulin imparts microtubule stability and potent in vivo activity.
    Risinger AL, Li J, Bennett MJ, Rohena CC, Peng J, Schriemer DC, Mooberry SL.
    Cancer Res; 2013 Nov 15; 73(22):6780-92. PubMed ID: 24048820
    [Abstract] [Full Text] [Related]

  • 15. Thymoquinone inhibits microtubule polymerization by tubulin binding and causes mitotic arrest following apoptosis in A549 cells.
    Acharya BR, Chatterjee A, Ganguli A, Bhattacharya S, Chakrabarti G.
    Biochimie; 2014 Feb 15; 97():78-91. PubMed ID: 24113316
    [Abstract] [Full Text] [Related]

  • 16. NMK-BH2, a novel microtubule-depolymerising bis (indolyl)-hydrazide-hydrazone, induces apoptotic and autophagic cell death in cervical cancer cells by binding to tubulin at colchicine - site.
    Das Mukherjee D, Kumar NM, Tantak MP, Datta S, Ghosh Dastidar D, Kumar D, Chakrabarti G.
    Biochim Biophys Acta Mol Cell Res; 2020 Oct 15; 1867(10):118762. PubMed ID: 32502617
    [Abstract] [Full Text] [Related]

  • 17. Colchicine Binding Site Agent DJ95 Overcomes Drug Resistance and Exhibits Antitumor Efficacy.
    Arnst KE, Wang Y, Lei ZN, Hwang DJ, Kumar G, Ma D, Parke DN, Chen Q, Yang J, White SW, Seagroves TN, Chen ZS, Miller DD, Li W.
    Mol Pharmacol; 2019 Jul 15; 96(1):73-89. PubMed ID: 31043459
    [Abstract] [Full Text] [Related]

  • 18. Microtubule Targeting Agents as Cancer Chemotherapeutics: An Overview of Molecular Hybrids as Stabilizing and Destabilizing Agents.
    Tangutur AD, Kumar D, Krishna KV, Kantevari S.
    Curr Top Med Chem; 2017 Jul 15; 17(22):2523-2537. PubMed ID: 28056738
    [Abstract] [Full Text] [Related]

  • 19. Griseofulvin stabilizes microtubule dynamics, activates p53 and inhibits the proliferation of MCF-7 cells synergistically with vinblastine.
    Rathinasamy K, Jindal B, Asthana J, Singh P, Balaji PV, Panda D.
    BMC Cancer; 2010 May 19; 10():213. PubMed ID: 20482847
    [Abstract] [Full Text] [Related]

  • 20. YSL-12, a novel microtubule-destabilizing agent, exerts potent anti-tumor activity against colon cancer in vitro and in vivo.
    Cai D, Qiu Z, Yao W, Liu Y, Huang H, Liao S, Luo Q, Xie L, Lin Z.
    Cancer Chemother Pharmacol; 2016 Jun 19; 77(6):1217-29. PubMed ID: 27107592
    [Abstract] [Full Text] [Related]

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