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156 related items for PubMed ID: 2114946

  • 1.
    ; . PubMed ID:
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  • 2. Differential toxicity of mitomycin C and porfiromycin to aerobic and hypoxic Chinese hamster ovary cells overexpressing human NADPH:cytochrome c (P-450) reductase.
    Belcourt MF, Hodnick WF, Rockwell S, Sartorelli AC.
    Proc Natl Acad Sci U S A; 1996 Jan 09; 93(1):456-60. PubMed ID: 8552660
    [Abstract] [Full Text] [Related]

  • 3. Activation of mitomycin C by NADPH:cytochrome P-450 reductase.
    Bligh HF, Bartoszek A, Robson CN, Hickson ID, Kasper CB, Beggs JD, Wolf CR.
    Cancer Res; 1990 Dec 15; 50(24):7789-92. PubMed ID: 2123741
    [Abstract] [Full Text] [Related]

  • 4. Characterization of a human bladder cancer cell line selected for resistance to BMY 25067, a novel analogue of mitomycin C.
    Singh SV, Xu BH, Gupta V, Emerson EO, Zaren HA, Jani JP.
    Cancer Lett; 1995 Aug 16; 95(1-2):49-56. PubMed ID: 7656243
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  • 5. Modification of the metabolism and cytotoxicity of bioreductive alkylating agents by dicoumarol in aerobic and hypoxic murine tumor cells.
    Keyes SR, Rockwell S, Sartorelli AC.
    Cancer Res; 1989 Jun 15; 49(12):3310-3. PubMed ID: 2470504
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  • 7. Exploring the mechanistic aspects of mitomycin antibiotic bioactivation in Chinese hamster ovary cells overexpressing NADPH:cytochrome C (P-450) reductase and DT-diaphorase.
    Belcourt MF, Hodnick WF, Rockwell S, Sartorelli AC.
    Adv Enzyme Regul; 1998 Jun 15; 38():111-33. PubMed ID: 9762350
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  • 9. Distinct roles of cytochrome P450 reductase in mitomycin C redox cycling and cytotoxicity.
    Wang Y, Gray JP, Mishin V, Heck DE, Laskin DL, Laskin JD.
    Mol Cancer Ther; 2010 Jun 15; 9(6):1852-63. PubMed ID: 20501808
    [Abstract] [Full Text] [Related]

  • 10. Reduced topoisomerase II and elevated alpha class glutathione S-transferase expression in a multidrug resistant CHO cell line highly cross-resistant to mitomycin C.
    Hoban PR, Robson CN, Davies SM, Hall AG, Cattan AR, Hickson ID, Harris AL.
    Biochem Pharmacol; 1992 Feb 18; 43(4):685-93. PubMed ID: 1311588
    [Abstract] [Full Text] [Related]

  • 11. Characterization of a set of Chinese hamster ovary variant cell lines demonstrating differing sensitivity to mitomycin C.
    Kuehl BL, Buchwald M, Rauth AM.
    Oncol Res; 1993 Feb 18; 5(6-7):213-21. PubMed ID: 8123941
    [Abstract] [Full Text] [Related]

  • 12. Metabolic activation of mitomycin C by liver microsomes and nuclei.
    Kennedy KA, Sligar SG, Polomski L, Sartorelli AC.
    Biochem Pharmacol; 1982 Jun 01; 31(11):2011-6. PubMed ID: 6810899
    [Abstract] [Full Text] [Related]

  • 13. One-electron reduction of mitomycin c by rat liver: role of cytochrome P-450 and NADPH-cytochrome P-450 reductase.
    Vromans RM, van de Straat R, Groeneveld M, Vermeulen NP.
    Xenobiotica; 1990 Sep 01; 20(9):967-78. PubMed ID: 2122607
    [Abstract] [Full Text] [Related]

  • 14. Chemotherapeutic attack of hypoxic tumor cells by the bioreductive alkylating agent mitomycin C.
    Keyes SR, Heimbrook DC, Fracasso PM, Rockwell S, Sligar SG, Sartorelli AC.
    Adv Enzyme Regul; 1985 Sep 01; 23():291-307. PubMed ID: 3934922
    [Abstract] [Full Text] [Related]

  • 15. Chinese hamster ovary cell lines resistant to mitomycin C under aerobic but not hypoxic conditions are deficient in DT-diaphorase.
    Dulhanty AM, Whitmore GF.
    Cancer Res; 1991 Apr 01; 51(7):1860-5. PubMed ID: 1900739
    [Abstract] [Full Text] [Related]

  • 16. Reversal of mitomycin C resistance by overexpression of bioreductive enzymes in Chinese hamster ovary cells.
    Baumann RP, Hodnick WF, Seow HA, Belcourt MF, Rockwell S, Sherman DH, Sartorelli AC.
    Cancer Res; 2001 Nov 01; 61(21):7770-6. PubMed ID: 11691791
    [Abstract] [Full Text] [Related]

  • 17. Cytotoxicity and DNA lesions produced by mitomycin C and porfiromycin in hypoxic and aerobic EMT6 and Chinese hamster ovary cells.
    Fracasso PM, Sartorelli AC.
    Cancer Res; 1986 Aug 01; 46(8):3939-44. PubMed ID: 3089583
    [Abstract] [Full Text] [Related]

  • 18. Effects of BMY 25282, a mitomycin C analogue, in mitomycin C-resistant human colon cancer cells.
    Willson JK, Long BH, Chakrabarty S, Brattain DE, Brattain MG.
    Cancer Res; 1985 Nov 01; 45(11 Pt 1):5281-6. PubMed ID: 3931904
    [Abstract] [Full Text] [Related]

  • 19. Mechanisms of hypoxic and aerobic cytotoxicity of mitomycin C in Chinese hamster V79 cells.
    Krishna MC, DeGraff W, Tamura S, Gonzalez FJ, Samuni A, Russo A, Mitchell JB.
    Cancer Res; 1991 Dec 15; 51(24):6622-8. PubMed ID: 1660344
    [Abstract] [Full Text] [Related]

  • 20. Modulation of sensitivity to mitomycin C and a dithiol analogue by tempol in non-small-cell lung cancer cell lines under hypoxia.
    Bando T, Kasahara K, Shibata K, Numata Y, Heki U, Shirasaki H, Iwasa K, Fujimura M, Matsuda T.
    J Cancer Res Clin Oncol; 1996 Dec 15; 122(1):21-6. PubMed ID: 8543588
    [Abstract] [Full Text] [Related]

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