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PUBMED FOR HANDHELDS

Journal Abstract Search


277 related items for PubMed ID: 21155690

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  • 4. Targeting glucokinase activation for the treatment of type 2 diabetes--a status review.
    Sarabu R, Grimsby J.
    Curr Opin Drug Discov Devel; 2005 Sep; 8(5):631-7. PubMed ID: 16159025
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  • 8. Novel, highly potent systemic glucokinase activators for the treatment of Type 2 Diabetes Mellitus.
    Xu J, Lin S, Myers RW, Addona G, Berger JP, Campbell B, Chen HS, Chen Z, Eiermann GJ, Elowe NH, Farrer BT, Feng W, Fu Q, Kats-Kagan R, Kavana M, Malkani S, McMasters DR, Mitra K, Pachanski MJ, Tong X, Trujillo ME, Xu L, Zhang B, Zhang F, Zhang R, Parmee ER.
    Bioorg Med Chem Lett; 2017 May 01; 27(9):2069-2073. PubMed ID: 28284804
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  • 9. Glucokinase activators: Novo Nordisk's WO2008084044 and Array Biopharma's WO2008091770.
    Tilley JW.
    Expert Opin Ther Pat; 2009 Apr 01; 19(4):549-53. PubMed ID: 19441933
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  • 10. Glucokinase activators in diabetes management.
    Coghlan M, Leighton B.
    Expert Opin Investig Drugs; 2008 Feb 01; 17(2):145-67. PubMed ID: 18230050
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  • 12. Discovery, structure-activity relationships, pharmacokinetics, and efficacy of glucokinase activator (2R)-3-cyclopentyl-2-(4-methanesulfonylphenyl)-N-thiazol-2-yl-propionamide (RO0281675).
    Haynes NE, Corbett WL, Bizzarro FT, Guertin KR, Hilliard DW, Holland GW, Kester RF, Mahaney PE, Qi L, Spence CL, Tengi J, Dvorozniak MT, Railkar A, Matschinsky FM, Grippo JF, Grimsby J, Sarabu R.
    J Med Chem; 2010 May 13; 53(9):3618-25. PubMed ID: 20405948
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  • 15. [Advances in the study of glucokinase and small molecule glucokinase activators].
    Li YQ, Feng ZQ, Song HR, Guo YS, Guo ZR.
    Yao Xue Xue Bao; 2006 May 13; 41(5):390-4. PubMed ID: 16848312
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  • 19. Discovery of orally active hepatoselective glucokinase activators for treatment of Type II Diabetes Mellitus.
    Xu J, Lin S, Myers RW, Trujillo ME, Pachanski MJ, Malkani S, Chen HS, Chen Z, Campbell B, Eiermann GJ, Elowe N, Farrer BT, Feng W, Fu Q, Kats-Kagan R, Kavana M, McMasters DR, Mitra K, Tong X, Xu L, Zhang F, Zhang R, Addona GH, Berger JP, Zhang B, Parmee ER.
    Bioorg Med Chem Lett; 2017 May 01; 27(9):2063-2068. PubMed ID: 28284809
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  • 20. Allosteric activators of glucokinase: potential role in diabetes therapy.
    Grimsby J, Sarabu R, Corbett WL, Haynes NE, Bizzarro FT, Coffey JW, Guertin KR, Hilliard DW, Kester RF, Mahaney PE, Marcus L, Qi L, Spence CL, Tengi J, Magnuson MA, Chu CA, Dvorozniak MT, Matschinsky FM, Grippo JF.
    Science; 2003 Jul 18; 301(5631):370-3. PubMed ID: 12869762
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