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Journal Abstract Search

132 related items for PubMed ID: 21185262

  • 1. Design, synthesis and DNA binding properties of orthogonally positioned diamino containing polyamide f-IPI.
    Babu B, Liu Y, Plaunt A, Riddering C, Ogilvie R, Westrate L, Davis R, Ferguson A, Mackay H, Rice T, Chavda S, Wilson D, Lin S, Kiakos K, Hartley JA, Lee M.
    Biochem Biophys Res Commun; 2011 Jan 21; 404(3):848-52. PubMed ID: 21185262
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  • 2. Novel diamino imidazole and pyrrole-containing polyamides: Synthesis and DNA binding studies of mono- and diamino-phenyl-ImPy*Im polyamides designed to target 5'-ACGCGT-3'.
    Satam V, Babu B, Chavda S, Savagian M, Sjoholm R, Tzou S, Ramos J, Liu Y, Kiakos K, Lin S, David Wilson W, Hartley JA, Lee M.
    Bioorg Med Chem; 2012 Jan 15; 20(2):693-701. PubMed ID: 22222156
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  • 5. Synthesis and DNA binding properties of 1-(3-aminopropyl)-imidazole-containing triamide f-Im*PyIm: a novel diamino polyamide designed to target 5'-ACGCGT-3'.
    Satam V, Babu B, Porte A, Savagian M, Lee M, Smeltzer T, Liu Y, Ramos J, Wilson WD, Lin S, Kiakos K, Hartley JA, Lee M.
    Bioorg Med Chem Lett; 2012 Sep 15; 22(18):5898-902. PubMed ID: 22892118
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  • 8. Modifying the N-terminus of polyamides: PyImPyIm has improved sequence specificity over f-ImPyIm.
    Brown T, Mackay H, Turlington M, Sutterfield A, Smith T, Sielaff A, Westrate L, Bruce C, Kluza J, O'Hare C, Nguyen B, Wilson WD, Hartley JA, Lee M.
    Bioorg Med Chem; 2008 May 01; 16(9):5266-76. PubMed ID: 18353654
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  • 9. Sequence specific and high affinity recognition of 5'-ACGCGT-3' by rationally designed pyrrole-imidazole H-pin polyamides: thermodynamic and structural studies.
    Mackay H, Brown T, Uthe PB, Westrate L, Sielaff A, Jones J, Lajiness JP, Kluza J, O'Hare C, Nguyen B, Davis Z, Bruce C, Wilson WD, Hartley JA, Lee M.
    Bioorg Med Chem; 2008 Oct 15; 16(20):9145-53. PubMed ID: 18819814
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  • 10. Synthesis and biophysical evaluation of minor-groove binding C-terminus modified pyrrole and imidazole triamide analogs of distamycin.
    Brown T, Taherbhai Z, Sexton J, Sutterfield A, Turlington M, Jones J, Stallings L, Stewart M, Buchmueller K, Mackay H, O'hare C, Kluza J, Nguyen B, Wilson D, Lee M, Hartley JA.
    Bioorg Med Chem; 2007 Jan 01; 15(1):474-83. PubMed ID: 17035029
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  • 11. Extending the language of DNA molecular recognition by polyamides: unexpected influence of imidazole and pyrrole arrangement on binding affinity and specificity.
    Buchmueller KL, Staples AM, Howard CM, Horick SM, Uthe PB, Le NM, Cox KK, Nguyen B, Pacheco KA, Wilson WD, Lee M.
    J Am Chem Soc; 2005 Jan 19; 127(2):742-50. PubMed ID: 15643900
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  • 13. Targeting the inverted CCAAT box 2 in the topoisomerase IIalpha promoter by JH-37, an imidazole-pyrrole polyamide hairpin: design, synthesis, molecular biology, and biophysical studies.
    Henry JA, Le NM, Nguyen B, Howard CM, Bailey SL, Horick SM, Buchmueller KL, Kotecha M, Hochhauser D, Hartley JA, Wilson WD, Lee M.
    Biochemistry; 2004 Sep 28; 43(38):12249-57. PubMed ID: 15379563
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  • 14. Rapid solid-phase synthesis of DNA-binding pyrrole-imidazole polyamides.
    Krutzik PO, Chamberlin AR.
    Bioorg Med Chem Lett; 2002 Aug 19; 12(16):2129-32. PubMed ID: 12127520
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  • 15. Conformational modulation of DNA by polyamide binding: structural effects of f-Im-Py-Im based derivatives on 5'-ACGCGT-3'.
    Wang S, Chai Y, Babu B, Satam V, Lee M, David Wilson W.
    J Mol Recognit; 2013 Aug 19; 26(8):331-40. PubMed ID: 23784989
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  • 16. AzaHx, a novel fluorescent, DNA minor groove and G·C recognition element: Synthesis and DNA binding properties of a p-anisyl-4-aza-benzimidazole-pyrrole-imidazole (azaHx-PI) polyamide.
    Satam V, Babu B, Patil P, Brien KA, Olson K, Savagian M, Lee M, Mepham A, Jobe LB, Bingham JP, Pett L, Wang S, Ferrara M, Bruce CD, Wilson WD, Lee M, Hartley JA, Kiakos K.
    Bioorg Med Chem Lett; 2015 Sep 01; 25(17):3681-5. PubMed ID: 26122210
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  • 17. [Advances in the chemical and biological studies of polyamides].
    Zhu SL, Gao PH, Li P, Jiang YY, Zhang DZ.
    Yao Xue Xue Bao; 2008 Nov 01; 43(11):1089-93. PubMed ID: 19239025
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  • 20. Recognition of the DNA minor groove by pyrrole-imidazole polyamides: comparison of desmethyl- and N-methylpyrrole.
    Bremer RE, Szewczyk JW, Baird EE, Dervan PB.
    Bioorg Med Chem; 2000 Aug 01; 8(8):1947-55. PubMed ID: 11003140
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