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Journal Abstract Search

125 related items for PubMed ID: 21185262

  • 1. Design, synthesis and DNA binding properties of orthogonally positioned diamino containing polyamide f-IPI.
    Babu B, Liu Y, Plaunt A, Riddering C, Ogilvie R, Westrate L, Davis R, Ferguson A, Mackay H, Rice T, Chavda S, Wilson D, Lin S, Kiakos K, Hartley JA, Lee M.
    Biochem Biophys Res Commun; 2011 Jan 21; 404(3):848-52. PubMed ID: 21185262
    [Abstract] [Full Text] [Related]

  • 2. Novel diamino imidazole and pyrrole-containing polyamides: Synthesis and DNA binding studies of mono- and diamino-phenyl-ImPy*Im polyamides designed to target 5'-ACGCGT-3'.
    Satam V, Babu B, Chavda S, Savagian M, Sjoholm R, Tzou S, Ramos J, Liu Y, Kiakos K, Lin S, David Wilson W, Hartley JA, Lee M.
    Bioorg Med Chem; 2012 Jan 15; 20(2):693-701. PubMed ID: 22222156
    [Abstract] [Full Text] [Related]

  • 3. Design, synthesis, and DNA binding characteristics of a group of orthogonally positioned diamino, N-formamido, pyrrole- and imidazole-containing polyamides.
    Chavda S, Babu B, Patil P, Plaunt A, Ferguson A, Lee M, Tzou S, Sjoholm R, Rice T, Mackay H, Ramos J, Wang S, Lin S, Kiakos K, Wilson WD, Hartley JA, Lee M.
    Bioorg Med Chem; 2013 Jul 01; 21(13):3907-18. PubMed ID: 23647824
    [Abstract] [Full Text] [Related]

  • 4. Effects of the N-terminal acylamido group of imidazole- and pyrrole-containing polyamides on DNA sequence specificity and binding affinity.
    Westrate L, Mackay H, Brown T, Nguyen B, Kluza J, Wilson WD, Lee M, Hartley JA.
    Biochemistry; 2009 Jun 23; 48(24):5679-88. PubMed ID: 19419200
    [Abstract] [Full Text] [Related]

  • 5. Synthesis and DNA binding properties of 1-(3-aminopropyl)-imidazole-containing triamide f-Im*PyIm: a novel diamino polyamide designed to target 5'-ACGCGT-3'.
    Satam V, Babu B, Porte A, Savagian M, Lee M, Smeltzer T, Liu Y, Ramos J, Wilson WD, Lin S, Kiakos K, Hartley JA, Lee M.
    Bioorg Med Chem Lett; 2012 Sep 15; 22(18):5898-902. PubMed ID: 22892118
    [Abstract] [Full Text] [Related]

  • 6. Sequence recognition in the minor groove of DNA by covalently linked formamido imidazole-pyrrole-imidazole polyamides: effect of H-pin linkage and linker length on selectivity and affinity.
    O'Hare CC, Uthe P, Mackay H, Blackmon K, Jones J, Brown T, Nguyen B, Wilson WD, Lee M, Hartley JA.
    Biochemistry; 2007 Oct 23; 46(42):11661-70. PubMed ID: 17910471
    [Abstract] [Full Text] [Related]

  • 7. Hx, a novel fluorescent, minor groove and sequence specific recognition element: design, synthesis, and DNA binding properties of p-anisylbenzimidazole-imidazole/pyrrole-containing polyamides.
    Chavda S, Liu Y, Babu B, Davis R, Sielaff A, Ruprich J, Westrate L, Tronrud C, Ferguson A, Franks A, Tzou S, Adkins C, Rice T, Mackay H, Kluza J, Tahir SA, Lin S, Kiakos K, Bruce CD, Wilson WD, Hartley JA, Lee M.
    Biochemistry; 2011 Apr 19; 50(15):3127-36. PubMed ID: 21388229
    [Abstract] [Full Text] [Related]

  • 8. Modifying the N-terminus of polyamides: PyImPyIm has improved sequence specificity over f-ImPyIm.
    Brown T, Mackay H, Turlington M, Sutterfield A, Smith T, Sielaff A, Westrate L, Bruce C, Kluza J, O'Hare C, Nguyen B, Wilson WD, Hartley JA, Lee M.
    Bioorg Med Chem; 2008 May 01; 16(9):5266-76. PubMed ID: 18353654
    [Abstract] [Full Text] [Related]

  • 9. Sequence specific and high affinity recognition of 5'-ACGCGT-3' by rationally designed pyrrole-imidazole H-pin polyamides: thermodynamic and structural studies.
    Mackay H, Brown T, Uthe PB, Westrate L, Sielaff A, Jones J, Lajiness JP, Kluza J, O'Hare C, Nguyen B, Davis Z, Bruce C, Wilson WD, Hartley JA, Lee M.
    Bioorg Med Chem; 2008 Oct 15; 16(20):9145-53. PubMed ID: 18819814
    [Abstract] [Full Text] [Related]

  • 10. Synthesis and biophysical evaluation of minor-groove binding C-terminus modified pyrrole and imidazole triamide analogs of distamycin.
    Brown T, Taherbhai Z, Sexton J, Sutterfield A, Turlington M, Jones J, Stallings L, Stewart M, Buchmueller K, Mackay H, O'hare C, Kluza J, Nguyen B, Wilson D, Lee M, Hartley JA.
    Bioorg Med Chem; 2007 Jan 01; 15(1):474-83. PubMed ID: 17035029
    [Abstract] [Full Text] [Related]

  • 11. Extending the language of DNA molecular recognition by polyamides: unexpected influence of imidazole and pyrrole arrangement on binding affinity and specificity.
    Buchmueller KL, Staples AM, Howard CM, Horick SM, Uthe PB, Le NM, Cox KK, Nguyen B, Pacheco KA, Wilson WD, Lee M.
    J Am Chem Soc; 2005 Jan 19; 127(2):742-50. PubMed ID: 15643900
    [Abstract] [Full Text] [Related]

  • 12. Polyamide curvature and DNA sequence selective recognition: use of 4-aminobenzamide to adjust curvature.
    Lajiness J, Sielaff A, Mackay H, Brown T, Kluza J, Nguyen B, Wilson WD, Lee M, Hartley JA.
    Med Chem; 2009 May 19; 5(3):216-26. PubMed ID: 19442211
    [Abstract] [Full Text] [Related]

  • 13. Targeting the inverted CCAAT box 2 in the topoisomerase IIalpha promoter by JH-37, an imidazole-pyrrole polyamide hairpin: design, synthesis, molecular biology, and biophysical studies.
    Henry JA, Le NM, Nguyen B, Howard CM, Bailey SL, Horick SM, Buchmueller KL, Kotecha M, Hochhauser D, Hartley JA, Wilson WD, Lee M.
    Biochemistry; 2004 Sep 28; 43(38):12249-57. PubMed ID: 15379563
    [Abstract] [Full Text] [Related]

  • 14. Rapid solid-phase synthesis of DNA-binding pyrrole-imidazole polyamides.
    Krutzik PO, Chamberlin AR.
    Bioorg Med Chem Lett; 2002 Aug 19; 12(16):2129-32. PubMed ID: 12127520
    [Abstract] [Full Text] [Related]

  • 15. Conformational modulation of DNA by polyamide binding: structural effects of f-Im-Py-Im based derivatives on 5'-ACGCGT-3'.
    Wang S, Chai Y, Babu B, Satam V, Lee M, David Wilson W.
    J Mol Recognit; 2013 Aug 19; 26(8):331-40. PubMed ID: 23784989
    [Abstract] [Full Text] [Related]

  • 16. AzaHx, a novel fluorescent, DNA minor groove and G·C recognition element: Synthesis and DNA binding properties of a p-anisyl-4-aza-benzimidazole-pyrrole-imidazole (azaHx-PI) polyamide.
    Satam V, Babu B, Patil P, Brien KA, Olson K, Savagian M, Lee M, Mepham A, Jobe LB, Bingham JP, Pett L, Wang S, Ferrara M, Bruce CD, Wilson WD, Lee M, Hartley JA, Kiakos K.
    Bioorg Med Chem Lett; 2015 Sep 01; 25(17):3681-5. PubMed ID: 26122210
    [Abstract] [Full Text] [Related]

  • 17. [Advances in the chemical and biological studies of polyamides].
    Zhu SL, Gao PH, Li P, Jiang YY, Zhang DZ.
    Yao Xue Xue Bao; 2008 Nov 01; 43(11):1089-93. PubMed ID: 19239025
    [Abstract] [Full Text] [Related]

  • 18. Influence of a terminal formamido group on the sequence recognition of DNA by polyamides.
    Lacy ER, Le NM, Price CA, Lee M, Wilson WD.
    J Am Chem Soc; 2002 Mar 13; 124(10):2153-63. PubMed ID: 11878969
    [Abstract] [Full Text] [Related]

  • 19. Physical and structural basis for the strong interactions of the -ImPy- central pairing motif in the polyamide f-ImPyIm.
    Buchmueller KL, Bailey SL, Matthews DA, Taherbhai ZT, Register JK, Davis ZS, Bruce CD, O'Hare C, Hartley JA, Lee M.
    Biochemistry; 2006 Nov 14; 45(45):13551-65. PubMed ID: 17087509
    [Abstract] [Full Text] [Related]

  • 20. Recognition of the DNA minor groove by pyrrole-imidazole polyamides: comparison of desmethyl- and N-methylpyrrole.
    Bremer RE, Szewczyk JW, Baird EE, Dervan PB.
    Bioorg Med Chem; 2000 Aug 14; 8(8):1947-55. PubMed ID: 11003140
    [Abstract] [Full Text] [Related]

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