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234 related items for PubMed ID: 2118992

  • 1. Cross-linking of T-cell surface molecules CD4 and CD8 stimulates phosphorylation of the lck tyrosine protein kinase at the autophosphorylation site.
    Luo KX, Sefton BM.
    Mol Cell Biol; 1990 Oct; 10(10):5305-13. PubMed ID: 2118992
    [Abstract] [Full Text] [Related]

  • 2. Requirement for kinase activity of CD4-associated p56lck in antibody-triggered T cell signal transduction.
    Chu K, Littman DR.
    J Biol Chem; 1994 Sep 30; 269(39):24095-101. PubMed ID: 7929062
    [Abstract] [Full Text] [Related]

  • 3. The CD4 associated tyrosine protein kinase p56lck is positively regulated through its site of autophosphorylation.
    Veillette A, Fournel M.
    Oncogene; 1990 Oct 30; 5(10):1455-62. PubMed ID: 2250907
    [Abstract] [Full Text] [Related]

  • 4. CD3-zeta surface expression is required for CD4-p56lck-mediated upregulation of T cell antigen receptor-CD3 signaling in T cells.
    Sancho J, Ledbetter JA, Choi MS, Kanner SB, Deans JP, Terhorst C.
    J Biol Chem; 1992 Apr 15; 267(11):7871-9. PubMed ID: 1532798
    [Abstract] [Full Text] [Related]

  • 5. Molecular interactions, T-cell subsets and a role of the CD4/CD8:p56lck complex in human T-cell activation.
    Rudd CE, Anderson P, Morimoto C, Streuli M, Schlossman SF.
    Immunol Rev; 1989 Oct 15; 111():225-66. PubMed ID: 2534114
    [Abstract] [Full Text] [Related]

  • 6. Human immunodeficiency virus gp120 and derived peptides activate protein tyrosine kinase p56lck in human CD4 T lymphocytes.
    Hivroz C, Mazerolles F, Soula M, Fagard R, Graton S, Meloche S, Sekaly RP, Fischer A.
    Eur J Immunol; 1993 Mar 15; 23(3):600-7. PubMed ID: 7680610
    [Abstract] [Full Text] [Related]

  • 7. Coclustering CD45 with CD4 or CD8 alters the phosphorylation and kinase activity of p56lck.
    Ostergaard HL, Trowbridge IS.
    J Exp Med; 1990 Jul 01; 172(1):347-50. PubMed ID: 2141630
    [Abstract] [Full Text] [Related]

  • 8. The CD4 and CD8 antigens are coupled to a protein-tyrosine kinase (p56lck) that phosphorylates the CD3 complex.
    Barber EK, Dasgupta JD, Schlossman SF, Trevillyan JM, Rudd CE.
    Proc Natl Acad Sci U S A; 1989 May 01; 86(9):3277-81. PubMed ID: 2470098
    [Abstract] [Full Text] [Related]

  • 9. The CD4-associated tyrosine kinase p56lck is required for lymphocyte chemoattractant factor-induced T lymphocyte migration.
    Ryan TC, Cruikshank WW, Kornfeld H, Collins TL, Center DM.
    J Biol Chem; 1995 Jul 21; 270(29):17081-6. PubMed ID: 7615501
    [Abstract] [Full Text] [Related]

  • 10. Decreased signaling competence as a result of receptor overexpression: overexpression of CD4 reduces its ability to activate p56lck tyrosine kinase and to regulate T-cell antigen receptor expression in immature CD4+CD8+ thymocytes.
    Nakayama T, Wiest DL, Abraham KM, Munitz TI, Perlmutter RM, Singer A.
    Proc Natl Acad Sci U S A; 1993 Nov 15; 90(22):10534-8. PubMed ID: 7902564
    [Abstract] [Full Text] [Related]

  • 11. Regulation of T cell receptor expression in immature CD4+CD8+ thymocytes by p56lck tyrosine kinase: basis for differential signaling by CD4 and CD8 in immature thymocytes expressing both coreceptor molecules.
    Wiest DL, Yuan L, Jefferson J, Benveniste P, Tsokos M, Klausner RD, Glimcher LH, Samelson LE, Singer A.
    J Exp Med; 1993 Nov 01; 178(5):1701-12. PubMed ID: 8228817
    [Abstract] [Full Text] [Related]

  • 12. Activated lck tyrosine protein kinase stimulates antigen-independent interleukin-2 production in T cells.
    Luo K, Sefton BM.
    Mol Cell Biol; 1992 Oct 01; 12(10):4724-32. PubMed ID: 1383689
    [Abstract] [Full Text] [Related]

  • 13. Enhancement of T-cell responsiveness by the lymphocyte-specific tyrosine protein kinase p56lck.
    Abraham N, Miceli MC, Parnes JR, Veillette A.
    Nature; 1991 Mar 07; 350(6313):62-6. PubMed ID: 1706070
    [Abstract] [Full Text] [Related]

  • 14. Activators of protein kinase C induce dissociation of CD4, but not CD8, from p56lck.
    Hurley TR, Luo K, Sefton BM.
    Science; 1989 Jul 28; 245(4916):407-9. PubMed ID: 2787934
    [Abstract] [Full Text] [Related]

  • 15. p56lck plays a key role in transducing apoptotic signals in T cells.
    Di Somma MM, Nuti S, Telford JL, Baldari CT.
    FEBS Lett; 1995 Apr 17; 363(1-2):101-4. PubMed ID: 7729528
    [Abstract] [Full Text] [Related]

  • 16. Engagement of CD4 and CD8 expressed on immature thymocytes induces activation of intracellular tyrosine phosphorylation pathways.
    Veillette A, Zúñiga-Pflücker JC, Bolen JB, Kruisbeek AM.
    J Exp Med; 1989 Nov 01; 170(5):1671-80. PubMed ID: 2478653
    [Abstract] [Full Text] [Related]

  • 17. Molecular analysis of the interaction of p56lck with the CD4 and CD8 antigens.
    Rudd CE, Barber EK, Burgess KE, Hahn JY, Odysseos AD, Sy MS, Schlossman SF.
    Adv Exp Med Biol; 1991 Nov 01; 292():85-96. PubMed ID: 1835265
    [Abstract] [Full Text] [Related]

  • 18. The lymphocyte-specific tyrosine protein kinase p56lck.
    Veillette A, Abraham N, Caron L, Davidson D.
    Semin Immunol; 1991 May 01; 3(3):143-52. PubMed ID: 1909593
    [Abstract] [Full Text] [Related]

  • 19. Tyrosine kinase activity of CD4-associated p56lck may not be required for CD4-dependent T-cell activation.
    Collins TL, Burakoff SJ.
    Proc Natl Acad Sci U S A; 1993 Dec 15; 90(24):11885-9. PubMed ID: 7505449
    [Abstract] [Full Text] [Related]

  • 20. The protein tyrosine kinase p56lck regulates thymocyte development independently of its interaction with CD4 and CD8 coreceptors [corrected].
    Levin SD, Abraham KM, Anderson SJ, Forbush KA, Perlmutter RM.
    J Exp Med; 1993 Jul 01; 178(1):245-55. PubMed ID: 8391060
    [Abstract] [Full Text] [Related]

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