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261 related items for PubMed ID: 21196469

  • 1. ESAT-6 secretion-independent impact of ESX-1 genes espF and espG1 on virulence of Mycobacterium tuberculosis.
    Bottai D, Majlessi L, Simeone R, Frigui W, Laurent C, Lenormand P, Chen J, Rosenkrands I, Huerre M, Leclerc C, Cole ST, Brosch R.
    J Infect Dis; 2011 Apr 15; 203(8):1155-64. PubMed ID: 21196469
    [Abstract] [Full Text] [Related]

  • 2. A non-RD1 gene cluster is required for Snm secretion in Mycobacterium tuberculosis.
    MacGurn JA, Raghavan S, Stanley SA, Cox JS.
    Mol Microbiol; 2005 Sep 15; 57(6):1653-63. PubMed ID: 16135231
    [Abstract] [Full Text] [Related]

  • 3. A unique Mycobacterium ESX-1 protein co-secretes with CFP-10/ESAT-6 and is necessary for inhibiting phagosome maturation.
    Xu J, Laine O, Masciocchi M, Manoranjan J, Smith J, Du SJ, Edwards N, Zhu X, Fenselau C, Gao LY.
    Mol Microbiol; 2007 Nov 15; 66(3):787-800. PubMed ID: 17908204
    [Abstract] [Full Text] [Related]

  • 4. A mycobacterial virulence gene cluster extending RD1 is required for cytolysis, bacterial spreading and ESAT-6 secretion.
    Gao LY, Guo S, McLaughlin B, Morisaki H, Engel JN, Brown EJ.
    Mol Microbiol; 2004 Sep 15; 53(6):1677-93. PubMed ID: 15341647
    [Abstract] [Full Text] [Related]

  • 5. A mycobacterium ESX-1-secreted virulence factor with unique requirements for export.
    McLaughlin B, Chon JS, MacGurn JA, Carlsson F, Cheng TL, Cox JS, Brown EJ.
    PLoS Pathog; 2007 Aug 03; 3(8):e105. PubMed ID: 17676952
    [Abstract] [Full Text] [Related]

  • 6. ESX/type VII secretion systems of mycobacteria: Insights into evolution, pathogenicity and protection.
    Simeone R, Bottai D, Frigui W, Majlessi L, Brosch R.
    Tuberculosis (Edinb); 2015 Jun 03; 95 Suppl 1():S150-4. PubMed ID: 25732627
    [Abstract] [Full Text] [Related]

  • 7. Recombinant BCG exporting ESAT-6 confers enhanced protection against tuberculosis.
    Pym AS, Brodin P, Majlessi L, Brosch R, Demangel C, Williams A, Griffiths KE, Marchal G, Leclerc C, Cole ST.
    Nat Med; 2003 May 03; 9(5):533-9. PubMed ID: 12692540
    [Abstract] [Full Text] [Related]

  • 8. C-terminal signal sequence promotes virulence factor secretion in Mycobacterium tuberculosis.
    Champion PA, Stanley SA, Champion MM, Brown EJ, Cox JS.
    Science; 2006 Sep 15; 313(5793):1632-6. PubMed ID: 16973880
    [Abstract] [Full Text] [Related]

  • 9. PPE and PE_PGRS proteins of Mycobacterium marinum are transported via the type VII secretion system ESX-5.
    Abdallah AM, Verboom T, Weerdenburg EM, Gey van Pittius NC, Mahasha PW, Jiménez C, Parra M, Cadieux N, Brennan MJ, Appelmelk BJ, Bitter W.
    Mol Microbiol; 2009 Aug 15; 73(3):329-40. PubMed ID: 19602152
    [Abstract] [Full Text] [Related]

  • 10. Enhanced protection against tuberculosis by vaccination with recombinant Mycobacterium microti vaccine that induces T cell immunity against region of difference 1 antigens.
    Brodin P, Majlessi L, Brosch R, Smith D, Bancroft G, Clark S, Williams A, Leclerc C, Cole ST.
    J Infect Dis; 2004 Jul 01; 190(1):115-22. PubMed ID: 15195250
    [Abstract] [Full Text] [Related]

  • 11. Mutually dependent secretion of proteins required for mycobacterial virulence.
    Fortune SM, Jaeger A, Sarracino DA, Chase MR, Sassetti CM, Sherman DR, Bloom BR, Rubin EJ.
    Proc Natl Acad Sci U S A; 2005 Jul 26; 102(30):10676-81. PubMed ID: 16030141
    [Abstract] [Full Text] [Related]

  • 12. Disruption of the ESX-5 system of Mycobacterium tuberculosis causes loss of PPE protein secretion, reduction of cell wall integrity and strong attenuation.
    Bottai D, Di Luca M, Majlessi L, Frigui W, Simeone R, Sayes F, Bitter W, Brennan MJ, Leclerc C, Batoni G, Campa M, Brosch R, Esin S.
    Mol Microbiol; 2012 Mar 26; 83(6):1195-209. PubMed ID: 22340629
    [Abstract] [Full Text] [Related]

  • 13. Evolution and expansion of the Mycobacterium tuberculosis PE and PPE multigene families and their association with the duplication of the ESAT-6 (esx) gene cluster regions.
    Gey van Pittius NC, Sampson SL, Lee H, Kim Y, van Helden PD, Warren RM.
    BMC Evol Biol; 2006 Nov 15; 6():95. PubMed ID: 17105670
    [Abstract] [Full Text] [Related]

  • 14. A novel ESX-1 locus reveals that surface-associated ESX-1 substrates mediate virulence in Mycobacterium marinum.
    Kennedy GM, Hooley GC, Champion MM, Mba Medie F, Champion PA.
    J Bacteriol; 2014 May 15; 196(10):1877-88. PubMed ID: 24610712
    [Abstract] [Full Text] [Related]

  • 15. Conserved ESX-1 Substrates EspE and EspF Are Virulence Factors That Regulate Gene Expression.
    Chirakos AE, Nicholson KR, Huffman A, Champion PA.
    Infect Immun; 2020 Nov 16; 88(12):. PubMed ID: 32900815
    [Abstract] [Full Text] [Related]

  • 16. Individual RD1-region genes are required for export of ESAT-6/CFP-10 and for virulence of Mycobacterium tuberculosis.
    Guinn KM, Hickey MJ, Mathur SK, Zakel KL, Grotzke JE, Lewinsohn DM, Smith S, Sherman DR.
    Mol Microbiol; 2004 Jan 16; 51(2):359-70. PubMed ID: 14756778
    [Abstract] [Full Text] [Related]

  • 17. The ESAT-6/CFP-10 secretion system of Mycobacterium marinum modulates phagosome maturation.
    Tan T, Lee WL, Alexander DC, Grinstein S, Liu J.
    Cell Microbiol; 2006 Sep 16; 8(9):1417-29. PubMed ID: 16922861
    [Abstract] [Full Text] [Related]

  • 18. EspR-dependent ESAT-6 Protein Secretion of Mycobacterium tuberculosis Requires the Presence of Virulence Regulator PhoP.
    Anil Kumar V, Goyal R, Bansal R, Singh N, Sevalkar RR, Kumar A, Sarkar D.
    J Biol Chem; 2016 Sep 02; 291(36):19018-30. PubMed ID: 27445330
    [Abstract] [Full Text] [Related]

  • 19. EspD is critical for the virulence-mediating ESX-1 secretion system in Mycobacterium tuberculosis.
    Chen JM, Boy-Röttger S, Dhar N, Sweeney N, Buxton RS, Pojer F, Rosenkrands I, Cole ST.
    J Bacteriol; 2012 Feb 02; 194(4):884-93. PubMed ID: 22155774
    [Abstract] [Full Text] [Related]

  • 20. A protein linkage map of the ESAT-6 secretion system 1 (ESX-1) of Mycobacterium tuberculosis.
    Teutschbein J, Schumann G, Möllmann U, Grabley S, Cole ST, Munder T.
    Microbiol Res; 2009 Feb 02; 164(3):253-9. PubMed ID: 17433643
    [Abstract] [Full Text] [Related]

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