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Journal Abstract Search

236 related items for PubMed ID: 2119830

  • 1. Comparison of intravenous bolus injection or continuous infusion of recombinant single chain urokinase-type plasminogen activator (saruplase) for thrombolysis. A canine model of combined coronary arterial and femoral venous thrombosis.
    Rapold HJ, Wu ZM, Stassen T, Van de Werf F, Collen D.
    Blood; 1990 Oct 15; 76(8):1558-63. PubMed ID: 2119830
    [Abstract] [Full Text] [Related]

  • 2. Comparative thrombolytic properties of tissue-type plasminogen activator (t-PA), single-chain urokinase-type plasminogen activator (u-PA) and K1K2Pu (a t-PA/u-PA chimera) in a combined arterial and venous thrombosis model in the dog.
    Lu HR, Wu Z, Pauwels P, Lijnen HR, Collen D.
    J Am Coll Cardiol; 1992 May 15; 19(6):1350-9. PubMed ID: 1342779
    [Abstract] [Full Text] [Related]

  • 3. Comparative thrombolytic properties of bolus injections and continuous infusions of a chimeric (t-PA/u-PA) plasminogen activator in a hamster pulmonary embolism model.
    Lu HR, Lijnen HR, Stassen JM, Collen D.
    Blood; 1991 Jul 01; 78(1):125-31. PubMed ID: 1906351
    [Abstract] [Full Text] [Related]

  • 4. Thrombolytic and pharmacokinetic properties of chimeric tissue-type and urokinase-type plasminogen activators.
    Collen D, Lu HR, Lijnen HR, Nelles L, Stassen JM.
    Circulation; 1991 Sep 01; 84(3):1216-34. PubMed ID: 1909220
    [Abstract] [Full Text] [Related]

  • 5. Thrombolysis with recombinant human single-chain urokinase-type plasminogen activator (rscu-PA): dose-response in dogs with coronary artery thrombosis.
    Van de Werf F, Jang IK, Collen D.
    J Cardiovasc Pharmacol; 1987 Jan 01; 9(1):91-3. PubMed ID: 2434801
    [Abstract] [Full Text] [Related]

  • 6. A novel chimaeric derivative of saruplase, rscu-PA-40 kDA/Hir, binds to thrombin and exerts thrombus-specific fibrinolysis in arterial and venous thrombosis in dogs.
    Schneider J, Hauser R, Hennies HH, Korioth J, Steffens G, Wnendt S.
    Thromb Haemost; 1997 Mar 01; 77(3):535-9. PubMed ID: 9066007
    [Abstract] [Full Text] [Related]

  • 7. Thrombolytic and pharmacokinetic properties of a conjugate of recombinant single-chain urokinase-type plasminogen activator with a monoclonal antibody specific for cross-linked fibrin in a baboon venous thrombosis model.
    Collen D, Dewerchin M, Rapold HJ, Lijnen HR, Stassen JM.
    Circulation; 1990 Nov 01; 82(5):1744-53. PubMed ID: 2121385
    [Abstract] [Full Text] [Related]

  • 8. Thrombolytic properties of human tissue-type plasminogen activator, single-chain urokinase-type plasminogen activator, and synergistic combinations in venous thrombosis models in dogs and rabbits.
    Spriggs DJ, Stassen JM, Hashimoto Y, Collen D.
    Blood; 1989 Apr 01; 73(5):1207-12. PubMed ID: 2495034
    [Abstract] [Full Text] [Related]

  • 9. Recombinant single-chain urokinase-type plasminogen activator (rscu-PA) induces thrombolysis and systemic fibrinolysis in a canine model of coronary artery thrombosis.
    Söhngen W, Mickelson JK, Simpson PJ, Lucchesi BR.
    Thromb Res; 1988 Jul 01; 51(1):63-74. PubMed ID: 3137691
    [Abstract] [Full Text] [Related]

  • 10. Bolus dose response characteristics of single chain urokinase plasminogen activator and tissue plasminogen activator in a dog model of arterial thrombosis.
    Badylak SF, Voytik S, Klabunde RE, Henkin J, Leski M.
    Thromb Res; 1988 Nov 15; 52(4):295-312. PubMed ID: 3144052
    [Abstract] [Full Text] [Related]

  • 11. Effect of chemical conjugation of recombinant single-chain urokinase-type plasminogen activator with monoclonal antiplatelet antibodies on platelet aggregation and on plasma clot lysis in vitro and in vivo.
    Dewerchin M, Lijnen HR, Stassen JM, De Cock F, Quertermous T, Ginsberg MH, Plow EF, Collen D.
    Blood; 1991 Aug 15; 78(4):1005-18. PubMed ID: 1831057
    [Abstract] [Full Text] [Related]

  • 12. Antithrombotic effects of thrombolytic agents in a platelet-rich femoral vein thrombosis model in the hamster.
    Stassen JM, Nyström A, Hoylaerts M, Collen D.
    Circulation; 1995 Mar 01; 91(5):1330-5. PubMed ID: 7867170
    [Abstract] [Full Text] [Related]

  • 13. Coronary arterial thrombolysis with low-dose synergistic combinations of recombinant tissue-type plasminogen activator (rt-PA) and recombinant single-chain urokinase-type plasminogen activator (rscu-PA) for acute myocardial infarction.
    Collen D, Van de Werf F.
    Am J Cardiol; 1987 Sep 01; 60(7):431-4. PubMed ID: 3115077
    [Abstract] [Full Text] [Related]

  • 14. Comparison of dose regimens for the administration of recombinant pro-urokinase in a canine thrombosis model.
    Burke SE, Lubbers NL, Nelson RA, Henkin J.
    Thromb Haemost; 1997 May 01; 77(5):1025-30. PubMed ID: 9184422
    [Abstract] [Full Text] [Related]

  • 15. Thrombolytic profiles of clot-targeted plasminogen activators. Parameters determining potency and initial and maximal rates.
    Holvoet P, Dewerchin M, Stassen JM, Lijnen HR, Tollenaere T, Gaffney PJ, Collen D.
    Circulation; 1993 Mar 01; 87(3):1007-16. PubMed ID: 8443877
    [Abstract] [Full Text] [Related]

  • 16. Synergistic combinations of recombinant human tissue-type plasminogen activator and human single-chain urokinase-type plasminogen activator. Effect on thrombolysis and reocclusion in a canine coronary artery thrombosis model with high-grade stenosis.
    Ziskind AA, Gold HK, Yasuda T, Kanke M, Guerrero JL, Fallon JT, Saito T, Collen D.
    Circulation; 1989 Feb 01; 79(2):393-9. PubMed ID: 2492455
    [Abstract] [Full Text] [Related]

  • 17. Thrombolytic and pharmacokinetic properties of an immunoconjugate of single-chain urokinase-type plasminogen activator (u-PA) and a bispecific monoclonal antibody against fibrin and against u-PA in baboons.
    Imura Y, Stassen JM, Kurokawa T, Iwasa S, Lijnen HR, Collen D.
    Blood; 1992 May 01; 79(9):2322-9. PubMed ID: 1571545
    [Abstract] [Full Text] [Related]

  • 18. Comparative studies of thrombolysis with single-chain and two-chain recombinant tissue-type plasminogen activators in canine coronary thrombosis.
    Yokoyama M, Ichikawa Y, Yatani A, Matsui K, Nakahara H, Kaneko M, Sakurama T, Ueshima S, Matsuo O.
    J Cardiovasc Pharmacol; 1996 Oct 01; 28(4):571-5. PubMed ID: 8891884
    [Abstract] [Full Text] [Related]

  • 19. Recombinant single-chain urokinase-type plasminogen activator during acute myocardial infarction.
    Diefenbach C, Erbel R, Pop T, Mathey D, Schofer J, Hamm C, Ostermann H, Schmitz-Hübner U, Bleifeld W, Meyer J.
    Am J Cardiol; 1988 May 01; 61(13):966-70. PubMed ID: 2452563
    [Abstract] [Full Text] [Related]

  • 20. Randomised double-blind trial of recombinant pro-urokinase against streptokinase in acute myocardial infarction. PRIMI Trial Study Group.
    Lancet; 1989 Apr 22; 1(8643):863-8. PubMed ID: 2564949
    [Abstract] [Full Text] [Related]

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