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198 related items for PubMed ID: 21204914

  • 1. Orange and apple juice greatly reduce the plasma concentrations of the OATP2B1 substrate aliskiren.
    Tapaninen T, Neuvonen PJ, Niemi M.
    Br J Clin Pharmacol; 2011 May; 71(5):718-26. PubMed ID: 21204914
    [Abstract] [Full Text] [Related]

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  • 3. Intestinal OATP1A2 inhibition as a potential mechanism for the effect of grapefruit juice on aliskiren pharmacokinetics in healthy subjects.
    Rebello S, Zhao S, Hariry S, Dahlke M, Alexander N, Vapurcuyan A, Hanna I, Jarugula V.
    Eur J Clin Pharmacol; 2012 May; 68(5):697-708. PubMed ID: 22124880
    [Abstract] [Full Text] [Related]

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  • 5. Itraconazole, a P-glycoprotein and CYP3A4 inhibitor, markedly raises the plasma concentrations and enhances the renin-inhibiting effect of aliskiren.
    Tapaninen T, Backman JT, Kurkinen KJ, Neuvonen PJ, Niemi M.
    J Clin Pharmacol; 2011 Mar; 51(3):359-67. PubMed ID: 20400651
    [Abstract] [Full Text] [Related]

  • 6. Effects of one-time apple juice ingestion on the pharmacokinetics of fexofenadine enantiomers.
    Akamine Y, Miura M, Komori H, Saito S, Kusuhara H, Tamai I, Ieiri I, Uno T, Yasui-Furukori N.
    Eur J Clin Pharmacol; 2014 Sep; 70(9):1087-95. PubMed ID: 24903351
    [Abstract] [Full Text] [Related]

  • 7. Fruit juices inhibit organic anion transporting polypeptide-mediated drug uptake to decrease the oral availability of fexofenadine.
    Dresser GK, Bailey DG, Leake BF, Schwarz UI, Dawson PA, Freeman DJ, Kim RB.
    Clin Pharmacol Ther; 2002 Jan; 71(1):11-20. PubMed ID: 11823753
    [Abstract] [Full Text] [Related]

  • 8. Major active components in grapefruit, orange, and apple juices responsible for OATP2B1-mediated drug interactions.
    Shirasaka Y, Shichiri M, Mori T, Nakanishi T, Tamai I.
    J Pharm Sci; 2013 Sep; 102(9):3418-26. PubMed ID: 23794501
    [Abstract] [Full Text] [Related]

  • 9. Apple juice greatly reduces systemic exposure to atenolol.
    Jeon H, Jang IJ, Lee S, Ohashi K, Kotegawa T, Ieiri I, Cho JY, Yoon SH, Shin SG, Yu KS, Lim KS.
    Br J Clin Pharmacol; 2013 Jan; 75(1):172-9. PubMed ID: 22574741
    [Abstract] [Full Text] [Related]

  • 10. Effects of orange juice on the pharmacokinetics of atenolol.
    Lilja JJ, Raaska K, Neuvonen PJ.
    Eur J Clin Pharmacol; 2005 Jul; 61(5-6):337-40. PubMed ID: 15983823
    [Abstract] [Full Text] [Related]

  • 11. A study of the pharmacokinetic interactions of the direct renin inhibitor aliskiren with metformin, pioglitazone and fenofibrate in healthy subjects.
    Vaidyanathan S, Maboudian M, Warren V, Yeh CM, Dieterich HA, Howard D, Dole WP.
    Curr Med Res Opin; 2008 Aug; 24(8):2313-26. PubMed ID: 18786303
    [Abstract] [Full Text] [Related]

  • 12. Aliskiren, a novel orally effective renin inhibitor, exhibits similar pharmacokinetics and pharmacodynamics in Japanese and Caucasian subjects.
    Vaidyanathan S, Jermany J, Yeh C, Bizot MN, Camisasca R.
    Br J Clin Pharmacol; 2006 Dec; 62(6):690-8. PubMed ID: 17118124
    [Abstract] [Full Text] [Related]

  • 13. SLCO2B1 c.935G>A single nucleotide polymorphism has no effect on the pharmacokinetics of montelukast and aliskiren.
    Tapaninen T, Karonen T, Backman JT, Neuvonen PJ, Niemi M.
    Pharmacogenet Genomics; 2013 Jan; 23(1):19-24. PubMed ID: 23151832
    [Abstract] [Full Text] [Related]

  • 14. Aliskiren exhibits similar pharmacokinetics in healthy volunteers and patients with type 2 diabetes mellitus.
    Zhao C, Vaidyanathan S, Yeh CM, Maboudian M, Armin Dieterich H.
    Clin Pharmacokinet; 2006 Jan; 45(11):1125-34. PubMed ID: 17048976
    [Abstract] [Full Text] [Related]

  • 15. Long-lasting inhibitory effect of apple and orange juices, but not grapefruit juice, on OATP2B1-mediated drug absorption.
    Shirasaka Y, Shichiri M, Murata Y, Mori T, Nakanishi T, Tamai I.
    Drug Metab Dispos; 2013 Mar; 41(3):615-21. PubMed ID: 23264447
    [Abstract] [Full Text] [Related]

  • 16. The effects of the SLCO2B1 c.1457C > T polymorphism and apple juice on the pharmacokinetics of fexofenadine and midazolam in humans.
    Imanaga J, Kotegawa T, Imai H, Tsutsumi K, Yoshizato T, Ohyama T, Shirasaka Y, Tamai I, Tateishi T, Ohashi K.
    Pharmacogenet Genomics; 2011 Feb; 21(2):84-93. PubMed ID: 21280267
    [Abstract] [Full Text] [Related]

  • 17. Influence of body weight and gender on the pharmacokinetics, pharmacodynamics, and antihypertensive efficacy of aliskiren.
    Jarugula V, Yeh CM, Howard D, Bush C, Keefe DL, Dole WP.
    J Clin Pharmacol; 2010 Dec; 50(12):1358-66. PubMed ID: 20150520
    [Abstract] [Full Text] [Related]

  • 18. Effect of ABCB1 haplotypes on the pharmacokinetics and renin-inhibiting effect of aliskiren.
    Tapaninen T, Neuvonen PJ, Niemi M.
    Eur J Clin Pharmacol; 2010 Sep; 66(9):865-70. PubMed ID: 20496145
    [Abstract] [Full Text] [Related]

  • 19. Orange juice substantially reduces the bioavailability of the beta-adrenergic-blocking agent celiprolol.
    Lilja JJ, Juntti-Patinen L, Neuvonen PJ.
    Clin Pharmacol Ther; 2004 Mar; 75(3):184-90. PubMed ID: 15001969
    [Abstract] [Full Text] [Related]

  • 20. Major active components in grapefruit, orange, and apple juices responsible for OATP2B1-mediated drug interactions.
    Shirasaka Y, Shichiri M, Mori T, Nakanishi T, Tamai I.
    J Pharm Sci; 2013 Jan; 102(1):280-8. PubMed ID: 23132664
    [Abstract] [Full Text] [Related]

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