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Journal Abstract Search

165 related items for PubMed ID: 21216217

  • 1. A rapid assay for assessment of sphingosine kinase inhibitors and substrates.
    Kharel Y, Mathews TP, Kennedy AJ, Houck JD, Macdonald TL, Lynch KR.
    Anal Biochem; 2011 Apr 15; 411(2):230-5. PubMed ID: 21216217
    [Abstract] [Full Text] [Related]

  • 2. Development of a simple and robust assay to screen for inhibitors of sphingosine kinases.
    Togame H, Dodo R, Inaoka T, Reinemer P.
    Assay Drug Dev Technol; 2007 Apr 15; 5(2):215-23. PubMed ID: 17477830
    [Abstract] [Full Text] [Related]

  • 3. Drugging sphingosine kinases.
    Santos WL, Lynch KR.
    ACS Chem Biol; 2015 Jan 16; 10(1):225-33. PubMed ID: 25384187
    [Abstract] [Full Text] [Related]

  • 4. Determination of sphingosine kinase activity in biological samples by liquid chromatography-tandem mass spectrometry.
    Lan T, Bi H, Xu S, Le K, Xie Z, Liu Y, Huang H.
    Biomed Chromatogr; 2010 Oct 16; 24(10):1075-83. PubMed ID: 20352614
    [Abstract] [Full Text] [Related]

  • 5. Sphingosine kinase assay system with fluorescent detection in high performance liquid chromatography.
    Jin YX, Yoo HS, Kihara A, Choi CH, Oh S, Moon DC, Igarashi Y, Lee YM.
    Arch Pharm Res; 2006 Nov 16; 29(11):1049-54. PubMed ID: 17146975
    [Abstract] [Full Text] [Related]

  • 6. An assay system for measuring the acute production of sphingosine 1-phosphate in intact monolayers.
    Siow DL, Wattenberg BW.
    Anal Biochem; 2007 Dec 15; 371(2):184-93. PubMed ID: 17884005
    [Abstract] [Full Text] [Related]

  • 7. Sphingosine kinase inhibitors: A patent review.
    Cao M, Ji C, Zhou Y, Huang W, Ni W, Tong X, Wei JF.
    Int J Mol Med; 2018 May 15; 41(5):2450-2460. PubMed ID: 29484372
    [Abstract] [Full Text] [Related]

  • 8. An Improved Isoform-Selective Assay for Sphingosine Kinase 1 Activity.
    Pitman MR, Davies LT, Pitson SM.
    Methods Mol Biol; 2018 May 15; 1697():9-20. PubMed ID: 28540558
    [Abstract] [Full Text] [Related]

  • 9. Isoform-selective assays for sphingosine kinase activity.
    Pitman MR, Pham DH, Pitson SM.
    Methods Mol Biol; 2012 May 15; 874():21-31. PubMed ID: 22528436
    [Abstract] [Full Text] [Related]

  • 10. Fluorescence-based assay of sphingosine kinases.
    Billich A, Ettmayer P.
    Anal Biochem; 2004 Mar 01; 326(1):114-9. PubMed ID: 14769343
    [Abstract] [Full Text] [Related]

  • 11. High-throughput screening assay for sphingosine kinase inhibitors in whole blood using RapidFire® mass spectrometry.
    Highkin MK, Yates MP, Nemirovskiy OV, Lamarr WA, Munie GE, Rains JW, Masferrer JL, Nagiec MM.
    J Biomol Screen; 2011 Feb 01; 16(2):272-7. PubMed ID: 21297110
    [Abstract] [Full Text] [Related]

  • 12. A rapid radioassay for sphingosine kinase.
    Vessey DA, Kelley M, Karliner JS.
    Anal Biochem; 2005 Feb 01; 337(1):136-42. PubMed ID: 15649386
    [Abstract] [Full Text] [Related]

  • 13. Building a better sphingosine kinase-1 inhibitor.
    Lynch KR.
    Biochem J; 2012 May 15; 444(1):e1-2. PubMed ID: 22533672
    [Abstract] [Full Text] [Related]

  • 14. Importance of sphingosine kinase (SphK) as a target in developing cancer therapeutics and recent developments in the synthesis of novel SphK inhibitors.
    Plano D, Amin S, Sharma AK.
    J Med Chem; 2014 Jul 10; 57(13):5509-24. PubMed ID: 24471412
    [Abstract] [Full Text] [Related]

  • 15. Structure guided design of a series of sphingosine kinase (SphK) inhibitors.
    Gustin DJ, Li Y, Brown ML, Min X, Schmitt MJ, Wanska M, Wang X, Connors R, Johnstone S, Cardozo M, Cheng AC, Jeffries S, Franks B, Li S, Shen S, Wong M, Wesche H, Xu G, Carlson TJ, Plant M, Morgenstern K, Rex K, Schmitt J, Coxon A, Walker N, Kayser F, Wang Z.
    Bioorg Med Chem Lett; 2013 Aug 15; 23(16):4608-16. PubMed ID: 23845219
    [Abstract] [Full Text] [Related]

  • 16. Anti-inflammatory effects of sphingosine kinase modulation in inflammatory arthritis.
    Lai WQ, Irwan AW, Goh HH, Howe HS, Yu DT, Valle-Oñate R, McInnes IB, Melendez AJ, Leung BP.
    J Immunol; 2008 Dec 01; 181(11):8010-7. PubMed ID: 19017993
    [Abstract] [Full Text] [Related]

  • 17. Synthesis and evaluation of sphingoid analogs as inhibitors of sphingosine kinases.
    Kim JW, Kim YW, Inagaki Y, Hwang YA, Mitsutake S, Ryu YW, Lee WK, Ha HJ, Park CS, Igarashi Y.
    Bioorg Med Chem; 2005 May 16; 13(10):3475-85. PubMed ID: 15848761
    [Abstract] [Full Text] [Related]

  • 18. Sphingosine Kinase 2 Inhibition and Blood Sphingosine 1-Phosphate Levels.
    Kharel Y, Morris EA, Congdon MD, Thorpe SB, Tomsig JL, Santos WL, Lynch KR.
    J Pharmacol Exp Ther; 2015 Oct 16; 355(1):23-31. PubMed ID: 26243740
    [Abstract] [Full Text] [Related]

  • 19. Sphingosine-1-phosphate: the Swiss army knife of sphingolipid signaling.
    Maceyka M, Milstien S, Spiegel S.
    J Lipid Res; 2009 Apr 16; 50 Suppl(Suppl):S272-6. PubMed ID: 18987387
    [Abstract] [Full Text] [Related]

  • 20. Development of amidine-based sphingosine kinase 1 nanomolar inhibitors and reduction of sphingosine 1-phosphate in human leukemia cells.
    Kennedy AJ, Mathews TP, Kharel Y, Field SD, Moyer ML, East JE, Houck JD, Lynch KR, Macdonald TL.
    J Med Chem; 2011 May 26; 54(10):3524-48. PubMed ID: 21495716
    [Abstract] [Full Text] [Related]

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