These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Journal Abstract Search

171 related items for PubMed ID: 21220532

  • 1. Importance of position 170 in the inhibition of GES-type β-lactamases by clavulanic acid.
    Frase H, Toth M, Champion MM, Antunes NT, Vakulenko SB.
    Antimicrob Agents Chemother; 2011 Apr; 55(4):1556-62. PubMed ID: 21220532
    [Abstract] [Full Text] [Related]

  • 2. Clavulanic acid inactivation of SHV-1 and the inhibitor-resistant S130G SHV-1 beta-lactamase. Insights into the mechanism of inhibition.
    Sulton D, Pagan-Rodriguez D, Zhou X, Liu Y, Hujer AM, Bethel CR, Helfand MS, Thomson JM, Anderson VE, Buynak JD, Ng LM, Bonomo RA.
    J Biol Chem; 2005 Oct 21; 280(42):35528-36. PubMed ID: 15987690
    [Abstract] [Full Text] [Related]

  • 3. Aspartic acid for asparagine substitution at position 276 reduces susceptibility to mechanism-based inhibitors in SHV-1 and SHV-5 beta-lactamases.
    Giakkoupi P, Tzelepi E, Legakis NJ, Tzouvelekis LS.
    J Antimicrob Chemother; 1999 Jan 21; 43(1):23-9. PubMed ID: 10381097
    [Abstract] [Full Text] [Related]

  • 4. Substitutions at position 105 in SHV family β-lactamases decrease catalytic efficiency and cause inhibitor resistance.
    Li M, Conklin BC, Taracila MA, Hutton RA, Skalweit MJ.
    Antimicrob Agents Chemother; 2012 Nov 21; 56(11):5678-86. PubMed ID: 22908166
    [Abstract] [Full Text] [Related]

  • 5. P174E Substitution in GES-1 and GES-5 β-Lactamases Improves Catalytic Efficiency toward Carbapenems.
    Piccirilli A, Mercuri PS, Galleni M, Aschi M, Matagne A, Amicosante G, Perilli M.
    Antimicrob Agents Chemother; 2018 May 21; 62(5):. PubMed ID: 29507065
    [Abstract] [Full Text] [Related]

  • 6. Carbapenem-hydrolyzing GES-type extended-spectrum beta-lactamase in Acinetobacter baumannii.
    Bonnin RA, Nordmann P, Potron A, Lecuyer H, Zahar JR, Poirel L.
    Antimicrob Agents Chemother; 2011 Jan 21; 55(1):349-54. PubMed ID: 20956589
    [Abstract] [Full Text] [Related]

  • 7. Substitution of Met-69 by Ala or Gly in TEM-1 beta-lactamase confer an increased susceptibility to clavulanic acid and other inhibitors.
    Madec S, Blin C, Krishnamoorthy R, Picard B, Chaibi el B, Fouchereau-Péron M, Labia R.
    FEMS Microbiol Lett; 2002 May 21; 211(1):13-6. PubMed ID: 12052544
    [Abstract] [Full Text] [Related]

  • 8. Understanding the molecular determinants of substrate and inhibitor specificities in the Carbapenemase KPC-2: exploring the roles of Arg220 and Glu276.
    Papp-Wallace KM, Taracila MA, Smith KM, Xu Y, Bonomo RA.
    Antimicrob Agents Chemother; 2012 Aug 21; 56(8):4428-38. PubMed ID: 22687511
    [Abstract] [Full Text] [Related]

  • 9. Mechanistic basis for the emergence of catalytic competence against carbapenem antibiotics by the GES family of beta-lactamases.
    Frase H, Shi Q, Testero SA, Mobashery S, Vakulenko SB.
    J Biol Chem; 2009 Oct 23; 284(43):29509-13. PubMed ID: 19656947
    [Abstract] [Full Text] [Related]

  • 10. The role of a second-shell residue in modifying substrate and inhibitor interactions in the SHV beta-lactamase: a study of ambler position Asn276.
    Drawz SM, Bethel CR, Hujer KM, Hurless KN, Distler AM, Caselli E, Prati F, Bonomo RA.
    Biochemistry; 2009 Jun 02; 48(21):4557-66. PubMed ID: 19351161
    [Abstract] [Full Text] [Related]

  • 11. Substrate selectivity and a novel role in inhibitor discrimination by residue 237 in the KPC-2 beta-lactamase.
    Papp-Wallace KM, Taracila M, Hornick JM, Hujer AM, Hujer KM, Distler AM, Endimiani A, Bonomo RA.
    Antimicrob Agents Chemother; 2010 Jul 02; 54(7):2867-77. PubMed ID: 20421396
    [Abstract] [Full Text] [Related]

  • 12. Laboratory Variants GESG170L, GESG170K, and GESG170H Increase Carbapenem Hydrolysis and Confer Resistance to Clavulanic Acid.
    Piccirilli A, Mercuri PS, Segatore B, Galleni M, Brisdelli F, Kerff F, Amicosante G, Perilli M.
    Antimicrob Agents Chemother; 2021 May 18; 65(6):. PubMed ID: 33722888
    [Abstract] [Full Text] [Related]

  • 13. Kinetic characterization of GES-22 β-lactamase harboring the M169L clinical mutation.
    Saral A, Leonard DA, Duzgun AO, Cicek AC, June CM, Sandalli C.
    J Antibiot (Tokyo); 2016 Dec 18; 69(12):858-862. PubMed ID: 27168312
    [Abstract] [Full Text] [Related]

  • 14. First virtual screening and experimental validation of inhibitors targeting GES-5 carbapenemase.
    Spyrakis F, Bellio P, Quotadamo A, Linciano P, Benedetti P, D'Arrigo G, Baroni M, Cendron L, Celenza G, Tondi D.
    J Comput Aided Mol Des; 2019 Feb 18; 33(2):295-305. PubMed ID: 30603820
    [Abstract] [Full Text] [Related]

  • 15.
    ; . PubMed ID:
    [No Abstract] [Full Text] [Related]

  • 16. Kinetic and crystallographic studies of extended-spectrum GES-11, GES-12, and GES-14 β-lactamases.
    Delbrück H, Bogaerts P, Kupper MB, Rezende de Castro R, Bennink S, Glupczynski Y, Galleni M, Hoffmann KM, Bebrone C.
    Antimicrob Agents Chemother; 2012 Nov 18; 56(11):5618-25. PubMed ID: 22908160
    [Abstract] [Full Text] [Related]

  • 17. Structure-function studies of arginine at position 276 in CTX-M beta-lactamases.
    Pérez-Llarena FJ, Cartelle M, Mallo S, Beceiro A, Pérez A, Villanueva R, Romero A, Bonnet R, Bou G.
    J Antimicrob Chemother; 2008 Apr 18; 61(4):792-7. PubMed ID: 18281307
    [Abstract] [Full Text] [Related]

  • 18. Inhibitor resistance in the KPC-2 beta-lactamase, a preeminent property of this class A beta-lactamase.
    Papp-Wallace KM, Bethel CR, Distler AM, Kasuboski C, Taracila M, Bonomo RA.
    Antimicrob Agents Chemother; 2010 Feb 18; 54(2):890-7. PubMed ID: 20008772
    [Abstract] [Full Text] [Related]

  • 19.
    ; . PubMed ID:
    [No Abstract] [Full Text] [Related]

  • 20. X-ray structure of the Asn276Asp variant of the Escherichia coli TEM-1 beta-lactamase: direct observation of electrostatic modulation in resistance to inactivation by clavulanic acid.
    Swarén P, Golemi D, Cabantous S, Bulychev A, Maveyraud L, Mobashery S, Samama JP.
    Biochemistry; 1999 Jul 27; 38(30):9570-6. PubMed ID: 10423234
    [Abstract] [Full Text] [Related]

    Page: [Next] [New Search]
    of 9.