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290 related items for PubMed ID: 21228337

  • 1. Phagocyte-like NADPH oxidase generates ROS in INS 832/13 cells and rat islets: role of protein prenylation.
    Syed I, Kyathanahalli CN, Kowluru A.
    Am J Physiol Regul Integr Comp Physiol; 2011 Mar; 300(3):R756-62. PubMed ID: 21228337
    [Abstract] [Full Text] [Related]

  • 2. Phagocyte-like NADPH oxidase (Nox2) promotes activation of p38MAPK in pancreatic β-cells under glucotoxic conditions: Evidence for a requisite role of Ras-related C3 botulinum toxin substrate 1 (Rac1).
    Sidarala V, Veluthakal R, Syeda K, Vlaar C, Newsholme P, Kowluru A.
    Biochem Pharmacol; 2015 Jun 15; 95(4):301-10. PubMed ID: 25881746
    [Abstract] [Full Text] [Related]

  • 3. Increased phagocyte-like NADPH oxidase and ROS generation in type 2 diabetic ZDF rat and human islets: role of Rac1-JNK1/2 signaling pathway in mitochondrial dysregulation in the diabetic islet.
    Syed I, Kyathanahalli CN, Jayaram B, Govind S, Rhodes CJ, Kowluru RA, Kowluru A.
    Diabetes; 2011 Nov 15; 60(11):2843-52. PubMed ID: 21911753
    [Abstract] [Full Text] [Related]

  • 4. Phagocyte-like NADPH oxidase promotes cytokine-induced mitochondrial dysfunction in pancreatic β-cells: evidence for regulation by Rac1.
    Subasinghe W, Syed I, Kowluru A.
    Am J Physiol Regul Integr Comp Physiol; 2011 Jan 15; 300(1):R12-20. PubMed ID: 20943855
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  • 6. A farnesylated G-protein suppresses Akt phosphorylation in INS 832/13 cells and normal rat islets: regulation by pertussis toxin and PGE₂.
    Kyathanahalli CN, Kowluru A.
    Biochem Pharmacol; 2011 May 15; 81(10):1237-47. PubMed ID: 21406184
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  • 8. Rac1-NADPH oxidase signaling promotes CD36 activation under glucotoxic conditions in pancreatic beta cells.
    Elumalai S, Karunakaran U, Lee IK, Moon JS, Won KC.
    Redox Biol; 2017 Apr 15; 11():126-134. PubMed ID: 27912197
    [Abstract] [Full Text] [Related]

  • 9. Friendly, and not so friendly, roles of Rac1 in islet β-cell function: lessons learnt from pharmacological and molecular biological approaches.
    Kowluru A.
    Biochem Pharmacol; 2011 Apr 15; 81(8):965-75. PubMed ID: 21300027
    [Abstract] [Full Text] [Related]

  • 10. Arf nucleotide binding site opener [ARNO] promotes sequential activation of Arf6, Cdc42 and Rac1 and insulin secretion in INS 832/13 β-cells and rat islets.
    Jayaram B, Syed I, Kyathanahalli CN, Rhodes CJ, Kowluru A.
    Biochem Pharmacol; 2011 Apr 15; 81(8):1016-27. PubMed ID: 21276423
    [Abstract] [Full Text] [Related]

  • 11. NADPH oxidase NOX2 defines a new antagonistic role for reactive oxygen species and cAMP/PKA in the regulation of insulin secretion.
    Li N, Li B, Brun T, Deffert-Delbouille C, Mahiout Z, Daali Y, Ma XJ, Krause KH, Maechler P.
    Diabetes; 2012 Nov 15; 61(11):2842-50. PubMed ID: 22933115
    [Abstract] [Full Text] [Related]

  • 12. Protein farnesylation-dependent Raf/extracellular signal-related kinase signaling links to cytoskeletal remodeling to facilitate glucose-induced insulin secretion in pancreatic beta-cells.
    Kowluru A, Veluthakal R, Rhodes CJ, Kamath V, Syed I, Koch BJ.
    Diabetes; 2010 Apr 15; 59(4):967-77. PubMed ID: 20071600
    [Abstract] [Full Text] [Related]

  • 13. Glucose activates the carboxyl methylation of gamma subunits of trimeric GTP-binding proteins in pancreatic beta cells. Modulation in vivo by calcium, GTP, and pertussis toxin.
    Kowluru A, Li G, Metz SA.
    J Clin Invest; 1997 Sep 15; 100(6):1596-610. PubMed ID: 9294129
    [Abstract] [Full Text] [Related]

  • 14. Glucose- and GTP-dependent stimulation of the carboxyl methylation of CDC42 in rodent and human pancreatic islets and pure beta cells. Evidence for an essential role of GTP-binding proteins in nutrient-induced insulin secretion.
    Kowluru A, Seavey SE, Li G, Sorenson RL, Weinhaus AJ, Nesher R, Rabaglia ME, Vadakekalam J, Metz SA.
    J Clin Invest; 1996 Jul 15; 98(2):540-55. PubMed ID: 8755667
    [Abstract] [Full Text] [Related]

  • 15. Isoprenylcysteine carboxyl methyltransferase facilitates glucose-induced Rac1 activation, ROS generation and insulin secretion in INS 832/13 β-cells.
    Jayaram B, Syed I, Singh A, Subasinghe W, Kyathanahalli CN, Kowluru A.
    Islets; 2011 Jul 15; 3(2):48-57. PubMed ID: 21346419
    [Abstract] [Full Text] [Related]

  • 16. TIAM1-RAC1 signalling axis-mediated activation of NADPH oxidase-2 initiates mitochondrial damage in the development of diabetic retinopathy.
    Kowluru RA, Kowluru A, Veluthakal R, Mohammad G, Syed I, Santos JM, Mishra M.
    Diabetologia; 2014 May 15; 57(5):1047-56. PubMed ID: 24554007
    [Abstract] [Full Text] [Related]

  • 17. Phagocytic NADPH oxidase links ARNO-Arf6 signaling pathway in glucose-stimulated insulin secretion from the pancreatic β-cell.
    Jayaram B, Kowluru A.
    Cell Physiol Biochem; 2012 May 15; 30(6):1351-62. PubMed ID: 23095975
    [Abstract] [Full Text] [Related]

  • 18. Glucose, palmitate and pro-inflammatory cytokines modulate production and activity of a phagocyte-like NADPH oxidase in rat pancreatic islets and a clonal beta cell line.
    Morgan D, Oliveira-Emilio HR, Keane D, Hirata AE, Santos da Rocha M, Bordin S, Curi R, Newsholme P, Carpinelli AR.
    Diabetologia; 2007 Feb 15; 50(2):359-69. PubMed ID: 17151863
    [Abstract] [Full Text] [Related]

  • 19. Association of NAD(P)H oxidase with glucose-induced insulin secretion by pancreatic beta-cells.
    Morgan D, Rebelato E, Abdulkader F, Graciano MF, Oliveira-Emilio HR, Hirata AE, Rocha MS, Bordin S, Curi R, Carpinelli AR.
    Endocrinology; 2009 May 15; 150(5):2197-201. PubMed ID: 19147679
    [Abstract] [Full Text] [Related]

  • 20. Control of Insulin Secretion by Production of Reactive Oxygen Species: Study Performed in Pancreatic Islets from Fed and 48-Hour Fasted Wistar Rats.
    Munhoz AC, Riva P, Simões D, Curi R, Carpinelli AR.
    PLoS One; 2016 May 15; 11(6):e0158166. PubMed ID: 27362938
    [Abstract] [Full Text] [Related]

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