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282 related items for PubMed ID: 21239852

  • 1. Transgenic AD model mice, effects of potential anti-AD treatments on inflammation, and pathology.
    van Groen T, Miettinen P, Kadish I.
    J Alzheimers Dis; 2011; 24(2):301-13. PubMed ID: 21239852
    [Abstract] [Full Text] [Related]

  • 2. Transgenic AD model mice, effects of potential anti-AD treatments on inflammation and pathology.
    van Groen T, Kadish I.
    Brain Res Brain Res Rev; 2005 Apr; 48(2):370-8. PubMed ID: 15850676
    [Abstract] [Full Text] [Related]

  • 3. Inflammation occurs early during the Abeta deposition process in TgCRND8 mice.
    Dudal S, Krzywkowski P, Paquette J, Morissette C, Lacombe D, Tremblay P, Gervais F.
    Neurobiol Aging; 2004 Aug; 25(7):861-71. PubMed ID: 15212840
    [Abstract] [Full Text] [Related]

  • 4. Activity of flurbiprofen and chemically related anti-inflammatory drugs in models of Alzheimer's disease.
    Gasparini L, Ongini E, Wilcock D, Morgan D.
    Brain Res Brain Res Rev; 2005 Apr; 48(2):400-8. PubMed ID: 15850679
    [Abstract] [Full Text] [Related]

  • 5. CHF5074, a novel gamma-secretase modulator, restores hippocampal neurogenesis potential and reverses contextual memory deficit in a transgenic mouse model of Alzheimer's disease.
    Imbimbo BP, Giardino L, Sivilia S, Giuliani A, Gusciglio M, Pietrini V, Del Giudice E, D'Arrigo A, Leon A, Villetti G, Calzà L.
    J Alzheimers Dis; 2010 Apr; 20(1):159-73. PubMed ID: 20164581
    [Abstract] [Full Text] [Related]

  • 6. Acute treatment with the PPARgamma agonist pioglitazone and ibuprofen reduces glial inflammation and Abeta1-42 levels in APPV717I transgenic mice.
    Heneka MT, Sastre M, Dumitrescu-Ozimek L, Hanke A, Dewachter I, Kuiperi C, O'Banion K, Klockgether T, Van Leuven F, Landreth GE.
    Brain; 2005 Jun; 128(Pt 6):1442-53. PubMed ID: 15817521
    [Abstract] [Full Text] [Related]

  • 7. 1-(3',4'-Dichloro-2-fluoro[1,1'-biphenyl]-4-yl)-cyclopropanecarboxylic acid (CHF5074), a novel gamma-secretase modulator, reduces brain beta-amyloid pathology in a transgenic mouse model of Alzheimer's disease without causing peripheral toxicity.
    Imbimbo BP, Del Giudice E, Colavito D, D'Arrigo A, Dalle Carbonare M, Villetti G, Facchinetti F, Volta R, Pietrini V, Baroc MF, Serneels L, De Strooper B, Leon A.
    J Pharmacol Exp Ther; 2007 Dec; 323(3):822-30. PubMed ID: 17895400
    [Abstract] [Full Text] [Related]

  • 8. Indirubin-3'-monoxime rescues spatial memory deficits and attenuates beta-amyloid-associated neuropathology in a mouse model of Alzheimer's disease.
    Ding Y, Qiao A, Fan GH.
    Neurobiol Dis; 2010 Aug; 39(2):156-68. PubMed ID: 20381617
    [Abstract] [Full Text] [Related]

  • 9. No improvement after chronic ibuprofen treatment in the 5XFAD mouse model of Alzheimer's disease.
    Hillmann A, Hahn S, Schilling S, Hoffmann T, Demuth HU, Bulic B, Schneider-Axmann T, Bayer TA, Weggen S, Wirths O.
    Neurobiol Aging; 2012 Apr; 33(4):833.e39-50. PubMed ID: 21943956
    [Abstract] [Full Text] [Related]

  • 10. Microglial activation and beta -amyloid deposit reduction caused by a nitric oxide-releasing nonsteroidal anti-inflammatory drug in amyloid precursor protein plus presenilin-1 transgenic mice.
    Jantzen PT, Connor KE, DiCarlo G, Wenk GL, Wallace JL, Rojiani AM, Coppola D, Morgan D, Gordon MN.
    J Neurosci; 2002 Mar 15; 22(6):2246-54. PubMed ID: 11896164
    [Abstract] [Full Text] [Related]

  • 11. Transplanted astrocytes internalize deposited beta-amyloid peptides in a transgenic mouse model of Alzheimer's disease.
    Pihlaja R, Koistinaho J, Malm T, Sikkilä H, Vainio S, Koistinaho M.
    Glia; 2008 Jan 15; 56(2):154-63. PubMed ID: 18004725
    [Abstract] [Full Text] [Related]

  • 12. Minocycline affects microglia activation, Abeta deposition, and behavior in APP-tg mice.
    Seabrook TJ, Jiang L, Maier M, Lemere CA.
    Glia; 2006 May 15; 53(7):776-82. PubMed ID: 16534778
    [Abstract] [Full Text] [Related]

  • 13. Non-steroidal anti-inflammatory drugs (NSAIDs) in Alzheimer's disease: old and new mechanisms of action.
    Gasparini L, Ongini E, Wenk G.
    J Neurochem; 2004 Nov 15; 91(3):521-36. PubMed ID: 15485484
    [Abstract] [Full Text] [Related]

  • 14. Activation of Wnt signaling by lithium and rosiglitazone reduced spatial memory impairment and neurodegeneration in brains of an APPswe/PSEN1DeltaE9 mouse model of Alzheimer's disease.
    Toledo EM, Inestrosa NC.
    Mol Psychiatry; 2010 Mar 15; 15(3):272-85, 228. PubMed ID: 19621015
    [Abstract] [Full Text] [Related]

  • 15. Bone-marrow-derived cells contribute to the recruitment of microglial cells in response to beta-amyloid deposition in APP/PS1 double transgenic Alzheimer mice.
    Malm TM, Koistinaho M, Pärepalo M, Vatanen T, Ooka A, Karlsson S, Koistinaho J.
    Neurobiol Dis; 2005 Feb 15; 18(1):134-42. PubMed ID: 15649704
    [Abstract] [Full Text] [Related]

  • 16. IFN-γ Production by amyloid β-specific Th1 cells promotes microglial activation and increases plaque burden in a mouse model of Alzheimer's disease.
    Browne TC, McQuillan K, McManus RM, O'Reilly JA, Mills KH, Lynch MA.
    J Immunol; 2013 Mar 01; 190(5):2241-51. PubMed ID: 23365075
    [Abstract] [Full Text] [Related]

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  • 19. Reversal of amyloid beta toxicity in Alzheimer's disease model Tg2576 by intraventricular antiamyloid beta antibody.
    Chauhan NB, Siegel GJ.
    J Neurosci Res; 2002 Jul 01; 69(1):10-23. PubMed ID: 12111811
    [Abstract] [Full Text] [Related]

  • 20. Noradrenaline deficiency in brain increases beta-amyloid plaque burden in an animal model of Alzheimer's disease.
    Kalinin S, Gavrilyuk V, Polak PE, Vasser R, Zhao J, Heneka MT, Feinstein DL.
    Neurobiol Aging; 2007 Aug 01; 28(8):1206-14. PubMed ID: 16837104
    [Abstract] [Full Text] [Related]

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