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3. A glutamine 67--> histidine mutation in homotetrameric R67 dihydrofolate reductase results in four mutations per single active site pore and causes substantial substrate and cofactor inhibition. Park H, Bradrick TD, Howell EE. Protein Eng; 1997 Dec; 10(12):1415-24. PubMed ID: 9543003 [Abstract] [Full Text] [Related]
11. Kinetic and molecular properties of the dihydrofolate reductase from pyrimethamine-sensitive and pyrimethamine-resistant clones of the human malaria parasite Plasmodium falciparum. Chen GX, Mueller C, Wendlinger M, Zolg JW. Mol Pharmacol; 1987 Apr 06; 31(4):430-7. PubMed ID: 3553892 [Abstract] [Full Text] [Related]
18. Effects of conversion of phenylalanine-31 to leucine on the function of human dihydrofolate reductase. Prendergast NJ, Appleman JR, Delcamp TJ, Blakley RL, Freisheim JH. Biochemistry; 1989 May 30; 28(11):4645-50. PubMed ID: 2765506 [Abstract] [Full Text] [Related]
19. Trypanosoma brucei dihydrofolate reductase-thymidylate synthase: gene isolation and expression and characterization of the enzyme. Gamarro F, Yu PL, Zhao J, Edman U, Greene PJ, Santi D. Mol Biochem Parasitol; 1995 Jun 30; 72(1-2):11-22. PubMed ID: 8538681 [Abstract] [Full Text] [Related]
20. Heterologous expression and characterization of the bifunctional dihydrofolate reductase-thymidylate synthase enzyme of Toxoplasma gondii. Trujillo M, Donald RG, Roos DS, Greene PJ, Santi DV. Biochemistry; 1996 May 21; 35(20):6366-74. PubMed ID: 8639582 [Abstract] [Full Text] [Related] Page: [Next] [New Search]