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Journal Abstract Search

244 related items for PubMed ID: 21245482

  • 41. Defective bone morphogenic protein signaling underlies hepcidin deficiency in HFE hereditary hemochromatosis.
    Ryan JD, Ryan E, Fabre A, Lawless MW, Crowe J.
    Hepatology; 2010 Oct; 52(4):1266-73. PubMed ID: 20658468
    [Abstract] [Full Text] [Related]

  • 42. Iron sensing as a partnership: HFE and transferrin receptor 2.
    Fleming RE.
    Cell Metab; 2009 Mar; 9(3):211-2. PubMed ID: 19254564
    [Abstract] [Full Text] [Related]

  • 43. Iron uptake from plasma transferrin by a transferrin receptor 2 mutant mouse model of haemochromatosis.
    Chua AC, Delima RD, Morgan EH, Herbison CE, Tirnitz-Parker JE, Graham RM, Fleming RE, Britton RS, Bacon BR, Olynyk JK, Trinder D.
    J Hepatol; 2010 Mar; 52(3):425-31. PubMed ID: 20133002
    [Abstract] [Full Text] [Related]

  • 44. Constitutive hepcidin expression prevents iron overload in a mouse model of hemochromatosis.
    Nicolas G, Viatte L, Lou DQ, Bennoun M, Beaumont C, Kahn A, Andrews NC, Vaulont S.
    Nat Genet; 2003 May; 34(1):97-101. PubMed ID: 12704388
    [Abstract] [Full Text] [Related]

  • 45. The transferrin receptor modulates Hfe-dependent regulation of hepcidin expression.
    Schmidt PJ, Toran PT, Giannetti AM, Bjorkman PJ, Andrews NC.
    Cell Metab; 2008 Mar; 7(3):205-14. PubMed ID: 18316026
    [Abstract] [Full Text] [Related]

  • 46. Hemochromatosis and pregnancy: iron stores in the Hfe-/- mouse are not reduced by multiple pregnancies.
    Neves JV, Olsson IA, Porto G, Rodrigues PN.
    Am J Physiol Gastrointest Liver Physiol; 2010 Apr; 298(4):G525-9. PubMed ID: 20110460
    [Abstract] [Full Text] [Related]

  • 47. Regulatory defects in liver and intestine implicate abnormal hepcidin and Cybrd1 expression in mouse hemochromatosis.
    Muckenthaler M, Roy CN, Custodio AO, Miñana B, deGraaf J, Montross LK, Andrews NC, Hentze MW.
    Nat Genet; 2003 May; 34(1):102-7. PubMed ID: 12704390
    [Abstract] [Full Text] [Related]

  • 48. [Non-HFE-related hereditary iron overload].
    Aguilar-Martinez P.
    Presse Med; 2007 Sep; 36(9 Pt 2):1279-91. PubMed ID: 17540536
    [Abstract] [Full Text] [Related]

  • 49. A competitive enzyme-linked immunosorbent assay specific for murine hepcidin-1: correlation with hepatic mRNA expression in established and novel models of dysregulated iron homeostasis.
    Gutschow P, Schmidt PJ, Han H, Ostland V, Bartnikas TB, Pettiglio MA, Herrera C, Butler JS, Nemeth E, Ganz T, Fleming MD, Westerman M.
    Haematologica; 2015 Feb; 100(2):167-77. PubMed ID: 25425686
    [Abstract] [Full Text] [Related]

  • 50. Cross-talk between the mitogen activated protein kinase and bone morphogenetic protein/hemojuvelin pathways is required for the induction of hepcidin by holotransferrin in primary mouse hepatocytes.
    Ramey G, Deschemin JC, Vaulont S.
    Haematologica; 2009 Jun; 94(6):765-72. PubMed ID: 19454495
    [Abstract] [Full Text] [Related]

  • 51. Hepcidin is decreased in TFR2 hemochromatosis.
    Nemeth E, Roetto A, Garozzo G, Ganz T, Camaschella C.
    Blood; 2005 Feb 15; 105(4):1803-6. PubMed ID: 15486069
    [Abstract] [Full Text] [Related]

  • 52. Transferrin receptor 2 and HFE regulate furin expression via mitogen-activated protein kinase/extracellular signal-regulated kinase (MAPK/Erk) signaling. Implications for transferrin-dependent hepcidin regulation.
    Poli M, Luscieti S, Gandini V, Maccarinelli F, Finazzi D, Silvestri L, Roetto A, Arosio P.
    Haematologica; 2010 Nov 15; 95(11):1832-40. PubMed ID: 20634490
    [Abstract] [Full Text] [Related]

  • 53. Human platelets express hemochromatosis protein (HFE) and transferrin receptor 2.
    Hannuksela J, Parkkila S, Waheed A, Britton RS, Fleming RE, Bacon BR, Sly WS.
    Eur J Haematol; 2003 Apr 15; 70(4):201-6. PubMed ID: 12656741
    [Abstract] [Full Text] [Related]

  • 54. The role of Hfe in transferrin-bound iron uptake by hepatocytes.
    Chua AC, Herbison CE, Drake SF, Graham RM, Olynyk JK, Trinder D.
    Hepatology; 2008 May 15; 47(5):1737-44. PubMed ID: 18393371
    [Abstract] [Full Text] [Related]

  • 55. Hfe and Hjv exhibit overlapping functions for iron signaling to hepcidin.
    Kent P, Wilkinson N, Constante M, Fillebeen C, Gkouvatsos K, Wagner J, Buffler M, Becker C, Schümann K, Santos MM, Pantopoulos K.
    J Mol Med (Berl); 2015 May 15; 93(5):489-98. PubMed ID: 25609138
    [Abstract] [Full Text] [Related]

  • 56. BMP/Smad signaling is not enhanced in Hfe-deficient mice despite increased Bmp6 expression.
    Kautz L, Meynard D, Besson-Fournier C, Darnaud V, Al Saati T, Coppin H, Roth MP.
    Blood; 2009 Sep 17; 114(12):2515-20. PubMed ID: 19622835
    [Abstract] [Full Text] [Related]

  • 57. HFE association with transferrin receptor 2 increases cellular uptake of transferrin-bound iron.
    Waheed A, Britton RS, Grubb JH, Sly WS, Fleming RE.
    Arch Biochem Biophys; 2008 Jun 01; 474(1):193-7. PubMed ID: 18353247
    [Abstract] [Full Text] [Related]

  • 58. Defective release of Hepcidin not defective synthesis is the primary pathogenic mechanism in HFE-Haemochromatosis.
    Arnold J, Sangwaiya A, Bhatkal B, Arnold A.
    Med Hypotheses; 2008 Jun 01; 70(6):1197-200. PubMed ID: 18054440
    [Abstract] [Full Text] [Related]

  • 59. Hereditary hemochromatosis protein, HFE, interaction with transferrin receptor 2 suggests a molecular mechanism for mammalian iron sensing.
    Goswami T, Andrews NC.
    J Biol Chem; 2006 Sep 29; 281(39):28494-8. PubMed ID: 16893896
    [Abstract] [Full Text] [Related]

  • 60. An Hfe-dependent pathway mediates hyposideremia in response to lipopolysaccharide-induced inflammation in mice.
    Roy CN, Custodio AO, de Graaf J, Schneider S, Akpan I, Montross LK, Sanchez M, Gaudino A, Hentze MW, Andrews NC, Muckenthaler MU.
    Nat Genet; 2004 May 29; 36(5):481-5. PubMed ID: 15098034
    [Abstract] [Full Text] [Related]

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