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Journal Abstract Search


190 related items for PubMed ID: 21246381

  • 1. β-Site APP-cleaving enzyme 1 (BACE1) cleaves cerebellar Na+ channel β4-subunit and promotes Purkinje cell firing by slowing the decay of resurgent Na+ current.
    Huth T, Rittger A, Saftig P, Alzheimer C.
    Pflugers Arch; 2011 Mar; 461(3):355-71. PubMed ID: 21246381
    [Abstract] [Full Text] [Related]

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  • 3. Control of transient, resurgent, and persistent current by open-channel block by Na channel beta4 in cultured cerebellar granule neurons.
    Bant JS, Raman IM.
    Proc Natl Acad Sci U S A; 2010 Jul 06; 107(27):12357-62. PubMed ID: 20566860
    [Abstract] [Full Text] [Related]

  • 4. Non-proteolytic effect of beta-site APP-cleaving enzyme 1 (BACE1) on sodium channel function.
    Huth T, Schmidt-Neuenfeldt K, Rittger A, Saftig P, Reiss K, Alzheimer C.
    Neurobiol Dis; 2009 Feb 06; 33(2):282-9. PubMed ID: 19056495
    [Abstract] [Full Text] [Related]

  • 5. A role for phosphorylation in the maintenance of resurgent sodium current in cerebellar purkinje neurons.
    Grieco TM, Afshari FS, Raman IM.
    J Neurosci; 2002 Apr 15; 22(8):3100-7. PubMed ID: 11943813
    [Abstract] [Full Text] [Related]

  • 6. Cross-species conservation of open-channel block by Na channel β4 peptides reveals structural features required for resurgent Na current.
    Lewis AH, Raman IM.
    J Neurosci; 2011 Aug 10; 31(32):11527-36. PubMed ID: 21832183
    [Abstract] [Full Text] [Related]

  • 7. Production of resurgent current in NaV1.6-null Purkinje neurons by slowing sodium channel inactivation with beta-pompilidotoxin.
    Grieco TM, Raman IM.
    J Neurosci; 2004 Jan 07; 24(1):35-42. PubMed ID: 14715935
    [Abstract] [Full Text] [Related]

  • 8. Effects of FGF14 and NaVβ4 deletion on transient and resurgent Na current in cerebellar Purkinje neurons.
    White HV, Brown ST, Bozza TC, Raman IM.
    J Gen Physiol; 2019 Nov 04; 151(11):1300-1318. PubMed ID: 31558566
    [Abstract] [Full Text] [Related]

  • 9. The contribution of resurgent sodium current to high-frequency firing in Purkinje neurons: an experimental and modeling study.
    Khaliq ZM, Gouwens NW, Raman IM.
    J Neurosci; 2003 Jun 15; 23(12):4899-912. PubMed ID: 12832512
    [Abstract] [Full Text] [Related]

  • 10. Open-channel block by the cytoplasmic tail of sodium channel beta4 as a mechanism for resurgent sodium current.
    Grieco TM, Malhotra JD, Chen C, Isom LL, Raman IM.
    Neuron; 2005 Jan 20; 45(2):233-44. PubMed ID: 15664175
    [Abstract] [Full Text] [Related]

  • 11. Intrinsic mechanisms in the gating of resurgent Na+ currents.
    Ransdell JL, Moreno JD, Bhagavan D, Silva JR, Nerbonne JM.
    Elife; 2022 Jan 25; 11():. PubMed ID: 35076394
    [Abstract] [Full Text] [Related]

  • 12. Reduced sodium channel Na(v)1.1 levels in BACE1-null mice.
    Kim DY, Gersbacher MT, Inquimbert P, Kovacs DM.
    J Biol Chem; 2011 Mar 11; 286(10):8106-8116. PubMed ID: 21190943
    [Abstract] [Full Text] [Related]

  • 13. Resurgent Na currents in four classes of neurons of the cerebellum.
    Afshari FS, Ptak K, Khaliq ZM, Grieco TM, Slater NT, McCrimmon DR, Raman IM.
    J Neurophysiol; 2004 Nov 11; 92(5):2831-43. PubMed ID: 15212420
    [Abstract] [Full Text] [Related]

  • 14. BACE1 modulates filopodia-like protrusions induced by sodium channel beta4 subunit.
    Miyazaki H, Oyama F, Wong HK, Kaneko K, Sakurai T, Tamaoka A, Nukina N.
    Biochem Biophys Res Commun; 2007 Sep 14; 361(1):43-8. PubMed ID: 17644063
    [Abstract] [Full Text] [Related]

  • 15. Alzheimer's secretases regulate voltage-gated sodium channels.
    Kovacs DM, Gersbacher MT, Kim DY.
    Neurosci Lett; 2010 Dec 10; 486(2):68-72. PubMed ID: 20817076
    [Abstract] [Full Text] [Related]

  • 16. Time-dependent block and resurgent tail currents induced by mouse beta4(154-167) peptide in cardiac Na+ channels.
    Wang GK, Edrich T, Wang SY.
    J Gen Physiol; 2006 Mar 10; 127(3):277-89. PubMed ID: 16505148
    [Abstract] [Full Text] [Related]

  • 17. Ion channel regulation by β-secretase BACE1 - enzymatic and non-enzymatic effects beyond Alzheimer's disease.
    Lehnert S, Hartmann S, Hessler S, Adelsberger H, Huth T, Alzheimer C.
    Channels (Austin); 2016 Sep 02; 10(5):365-378. PubMed ID: 27253079
    [Abstract] [Full Text] [Related]

  • 18. Antagonism of lidocaine inhibition by open-channel blockers that generate resurgent Na current.
    Bant JS, Aman TK, Raman IM.
    J Neurosci; 2013 Mar 13; 33(11):4976-87. PubMed ID: 23486968
    [Abstract] [Full Text] [Related]

  • 19. Inwardly permeating Na ions generate the voltage dependence of resurgent Na current in cerebellar Purkinje neurons.
    Aman TK, Raman IM.
    J Neurosci; 2010 Apr 21; 30(16):5629-34. PubMed ID: 20410115
    [Abstract] [Full Text] [Related]

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