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184 related items for PubMed ID: 21254354

  • 1. High intake of folic acid disrupts embryonic development in mice.
    Pickell L, Brown K, Li D, Wang XL, Deng L, Wu Q, Selhub J, Luo L, Jerome-Majewska L, Rozen R.
    Birth Defects Res A Clin Mol Teratol; 2011 Jan; 91(1):8-19. PubMed ID: 21254354
    [Abstract] [Full Text] [Related]

  • 2. Methylenetetrahydrofolate reductase deficiency and low dietary folate increase embryonic delay and placental abnormalities in mice.
    Pickell L, Li D, Brown K, Mikael LG, Wang XL, Wu Q, Luo L, Jerome-Majewska L, Rozen R.
    Birth Defects Res A Clin Mol Teratol; 2009 Jun; 85(6):531-41. PubMed ID: 19215022
    [Abstract] [Full Text] [Related]

  • 3. Moderately high intake of folic acid has a negative impact on mouse embryonic development.
    Mikael LG, Deng L, Paul L, Selhub J, Rozen R.
    Birth Defects Res A Clin Mol Teratol; 2013 Jan; 97(1):47-52. PubMed ID: 23125102
    [Abstract] [Full Text] [Related]

  • 4. Embryonic development in the reduced folate carrier knockout mouse is modulated by maternal folate supplementation.
    Gelineau-van Waes J, Heller S, Bauer LK, Wilberding J, Maddox JR, Aleman F, Rosenquist TH, Finnell RH.
    Birth Defects Res A Clin Mol Teratol; 2008 Jul; 82(7):494-507. PubMed ID: 18383508
    [Abstract] [Full Text] [Related]

  • 5. Methylenetetrahydrofolate reductase deficiency and low dietary folate reduce tumorigenesis in Apc min/+ mice.
    Lawrance AK, Deng L, Rozen R.
    Gut; 2009 Jun; 58(6):805-11. PubMed ID: 19174418
    [Abstract] [Full Text] [Related]

  • 6. Moderate folic acid supplementation and MTHFD1-synthetase deficiency in mice, a model for the R653Q variant, result in embryonic defects and abnormal placental development.
    Christensen KE, Hou W, Bahous RH, Deng L, Malysheva OV, Arning E, Bottiglieri T, Caudill MA, Jerome-Majewska LA, Rozen R.
    Am J Clin Nutr; 2016 Nov; 104(5):1459-1469. PubMed ID: 27707701
    [Abstract] [Full Text] [Related]

  • 7. Maternal methylenetetrahydrofolate reductase deficiency and low dietary folate lead to adverse reproductive outcomes and congenital heart defects in mice.
    Li D, Pickell L, Liu Y, Wu Q, Cohn JS, Rozen R.
    Am J Clin Nutr; 2005 Jul; 82(1):188-95. PubMed ID: 16002818
    [Abstract] [Full Text] [Related]

  • 8. Maternal MTHFR 677C>T is a risk factor for congenital heart defects: effect modification by periconceptional folate supplementation.
    van Beynum IM, Kapusta L, den Heijer M, Vermeulen SH, Kouwenberg M, Daniëls O, Blom HJ.
    Eur Heart J; 2006 Apr; 27(8):981-7. PubMed ID: 16524890
    [Abstract] [Full Text] [Related]

  • 9. Folate supplementation induces differential dose-dependent modulation of proliferative phenotypes among cancerous and noncancerous oral cell lines in vitro.
    McCabe J, Chang S, Hajibandeh J, Tran MD, Meeder CA, Sharma K, Nguyen DH, Moody M, Keiserman MA, Bergman CJ, Kingsley K.
    J Diet Suppl; 2010 Dec; 7(4):325-40. PubMed ID: 22432562
    [Abstract] [Full Text] [Related]

  • 10. Folic acid use in pregnancy and embryo selection.
    Haggarty P, Campbell DM, Duthie S, Andrews K, Hoad G, Piyathilake C, Fraser I, McNeill G.
    BJOG; 2008 Jun; 115(7):851-6. PubMed ID: 18485163
    [Abstract] [Full Text] [Related]

  • 11. Influence of maternal folate status on the developmental toxicity of methanol in the CD-1 mouse.
    Sakanashi TM, Rogers JM, Fu SS, Connelly LE, Keen CL.
    Teratology; 1996 Oct; 54(4):198-206. PubMed ID: 9122889
    [Abstract] [Full Text] [Related]

  • 12. Effect of supplemental folic acid on valproic acid-induced embryotoxicity and tissue zinc levels in vivo.
    Hansen DK, Grafton TF, Dial SL, Gehring TA, Siitonen PH.
    Teratology; 1995 Nov; 52(5):277-85. PubMed ID: 8838251
    [Abstract] [Full Text] [Related]

  • 13. Non-optimal maturation of the oocyte, maternal MTHFR polymorphisms, periconceptional folate, and decrease of congenital heart defects.
    Jongbloet PH.
    Eur Heart J; 2007 Aug; 28(16):2043. PubMed ID: 17575269
    [No Abstract] [Full Text] [Related]

  • 14. Low Dietary Folate Interacts with MTHFD1 Synthetase Deficiency in Mice, a Model for the R653Q Variant, to Increase Incidence of Developmental Delays and Defects.
    Christensen KE, Bahous RH, Hou W, Deng L, Malysheva OV, Arning E, Bottiglieri T, Caudill MA, Jerome-Majewska LA, Rozen R.
    J Nutr; 2018 Apr 01; 148(4):501-509. PubMed ID: 29659962
    [Abstract] [Full Text] [Related]

  • 15. Homocysteine, folate, and congenital heart defects.
    Huhta JC, Hernandez-Robles JA.
    Fetal Pediatr Pathol; 2005 Apr 01; 24(2):71-9. PubMed ID: 16243751
    [Abstract] [Full Text] [Related]

  • 16. High dietary folate in pregnant mice leads to pseudo-MTHFR deficiency and altered methyl metabolism, with embryonic growth delay and short-term memory impairment in offspring.
    Bahous RH, Jadavji NM, Deng L, Cosín-Tomás M, Lu J, Malysheva O, Leung KY, Ho MK, Pallàs M, Kaliman P, Greene NDE, Bedell BJ, Caudill MA, Rozen R.
    Hum Mol Genet; 2017 Mar 01; 26(5):888-900. PubMed ID: 28069796
    [Abstract] [Full Text] [Related]

  • 17. The effects of periconceptional folic acid and vitamin supplementation on maternal folate levels and on neurulating hamster embryos in vivo.
    Mooij PN, Thomas CM, Doesburg WH, Eskes TK.
    Int J Vitam Nutr Res; 1993 Mar 01; 63(3):212-6. PubMed ID: 8300333
    [Abstract] [Full Text] [Related]

  • 18. Evaluation of infant methylenetetrahydrofolate reductase genotype, maternal vitamin use, and risk of high versus low level spina bifida defects.
    Volcik KA, Shaw GM, Lammer EJ, Zhu H, Finnell RH.
    Birth Defects Res A Clin Mol Teratol; 2003 Mar 01; 67(3):154-7. PubMed ID: 12797455
    [Abstract] [Full Text] [Related]

  • 19. Moderate Folic Acid Supplementation in Pregnant Mice Results in Altered Methyl Metabolism and in Sex-Specific Placental Transcription Changes.
    Luan Y, Leclerc D, Cosín-Tomás M, Malysheva OV, Wasek B, Bottiglieri T, Caudill MA, Rozen R.
    Mol Nutr Food Res; 2021 Jul 01; 65(14):e2100197. PubMed ID: 34010503
    [Abstract] [Full Text] [Related]

  • 20. Folic acid: miscarriages, anomalies, thromboses, cancers.
    Thurmon TF.
    J La State Med Soc; 2001 Feb 01; 153(2):98-103. PubMed ID: 11261364
    [Abstract] [Full Text] [Related]

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