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Journal Abstract Search

153 related items for PubMed ID: 2125487

  • 1. X-ray crystal structure of the protease inhibitor domain of Alzheimer's amyloid beta-protein precursor.
    Hynes TR, Randal M, Kennedy LA, Eigenbrot C, Kossiakoff AA.
    Biochemistry; 1990 Oct 30; 29(43):10018-22. PubMed ID: 2125487
    [Abstract] [Full Text] [Related]

  • 2. Crystal structures of bovine chymotrypsin and trypsin complexed to the inhibitor domain of Alzheimer's amyloid beta-protein precursor (APPI) and basic pancreatic trypsin inhibitor (BPTI): engineering of inhibitors with altered specificities.
    Scheidig AJ, Hynes TR, Pelletier LA, Wells JA, Kossiakoff AA.
    Protein Sci; 1997 Sep 30; 6(9):1806-24. PubMed ID: 9300481
    [Abstract] [Full Text] [Related]

  • 3. Structure prediction of protease inhibitor region in amyloid precursor protein of Alzheimer's disease.
    Toma K, Kitaguchi N, Ito H.
    J Mol Graph; 1989 Dec 30; 7(4):202-5, 217-8. PubMed ID: 2484810
    [Abstract] [Full Text] [Related]

  • 4. Sequential NMR resonance assignment and structure determination of the Kunitz-type inhibitor domain of the Alzheimer's beta-amyloid precursor protein.
    Heald SL, Tilton RF, Hammond LJ, Lee A, Bayney RM, Kamarck ME, Ramabhadran TV, Dreyer RN, Davis G, Unterbeck A.
    Biochemistry; 1991 Oct 29; 30(43):10467-78. PubMed ID: 1718421
    [Abstract] [Full Text] [Related]

  • 5. Determinants of affinity and proteolytic stability in interactions of Kunitz family protease inhibitors with mesotrypsin.
    Salameh MA, Soares AS, Navaneetham D, Sinha D, Walsh PN, Radisky ES.
    J Biol Chem; 2010 Nov 19; 285(47):36884-96. PubMed ID: 20861008
    [Abstract] [Full Text] [Related]

  • 6. Synthesis and characterization of the Kunitz protease-inhibitor domain of the beta-amyloid precursor protein.
    Schilling J, Wang Y, Lau K, Smith L, Cordell B.
    Gene; 1991 Feb 15; 98(2):225-30. PubMed ID: 1707846
    [Abstract] [Full Text] [Related]

  • 7. Enzyme specificity of proteinase inhibitor region in amyloid precursor protein of Alzheimer's disease: different properties compared with protease nexin I.
    Kitaguchi N, Takahashi Y, Oishi K, Shiojiri S, Tokushima Y, Utsunomiya T, Ito H.
    Biochim Biophys Acta; 1990 Mar 29; 1038(1):105-13. PubMed ID: 2180485
    [Abstract] [Full Text] [Related]

  • 8. Glycosylation of the amyloid peptide precursor containing the Kunitz protease inhibitor domain improves the inhibition of trypsin.
    Godfroid E, Octave JN.
    Biochem Biophys Res Commun; 1990 Sep 28; 171(3):1015-21. PubMed ID: 2121136
    [Abstract] [Full Text] [Related]

  • 9. Disulfide engineering of human Kunitz-type serine protease inhibitors enhances proteolytic stability and target affinity toward mesotrypsin.
    Cohen I, Coban M, Shahar A, Sankaran B, Hockla A, Lacham S, Caulfield TR, Radisky ES, Papo N.
    J Biol Chem; 2019 Mar 29; 294(13):5105-5120. PubMed ID: 30700553
    [Abstract] [Full Text] [Related]

  • 10. Sequence and conformational specificity in substrate recognition: several human Kunitz protease inhibitor domains are specific substrates of mesotrypsin.
    Pendlebury D, Wang R, Henin RD, Hockla A, Soares AS, Madden BJ, Kazanov MD, Radisky ES.
    J Biol Chem; 2014 Nov 21; 289(47):32783-97. PubMed ID: 25301953
    [Abstract] [Full Text] [Related]

  • 11. Determination of amyloid beta protein precursors harboring active form of proteinase inhibitor domains in cerebrospinal fluid of Alzheimer's disease patients by trypsin-antibody sandwich ELISA.
    Kitaguchi N, Tokushima Y, Oishi K, Takahashi Y, Shiojiri S, Nakamura S, Tanaka S, Kodaira R, Ito H.
    Biochem Biophys Res Commun; 1990 Feb 14; 166(3):1453-9. PubMed ID: 2106318
    [Abstract] [Full Text] [Related]

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  • 14. The amyloid precursor protein/protease nexin 2 Kunitz inhibitor domain is a highly specific substrate of mesotrypsin.
    Salameh MA, Robinson JL, Navaneetham D, Sinha D, Madden BJ, Walsh PN, Radisky ES.
    J Biol Chem; 2010 Jan 15; 285(3):1939-49. PubMed ID: 19920152
    [Abstract] [Full Text] [Related]

  • 15. The secreted form of the Alzheimer's amyloid precursor protein with the Kunitz domain is protease nexin-II.
    Oltersdorf T, Fritz LC, Schenk DB, Lieberburg I, Johnson-Wood KL, Beattie EC, Ward PJ, Blacher RW, Dovey HF, Sinha S.
    Nature; 1989 Sep 14; 341(6238):144-7. PubMed ID: 2506449
    [Abstract] [Full Text] [Related]

  • 16. Does the Kunitz domain from the Alzheimer's amyloid beta protein precursor inhibit a kallikrein responsible for post-translational processing of nerve growth factor precursor?
    Castro M, Marks CB, Nilsson B, Anderson S.
    FEBS Lett; 1990 Jul 16; 267(2):207-12. PubMed ID: 1696210
    [Abstract] [Full Text] [Related]

  • 17. Pre-equilibrium competitive library screening for tuning inhibitor association rate and specificity toward serine proteases.
    Cohen I, Naftaly S, Ben-Zeev E, Hockla A, Radisky ES, Papo N.
    Biochem J; 2018 Apr 16; 475(7):1335-1352. PubMed ID: 29535275
    [Abstract] [Full Text] [Related]

  • 18. A new A4 amyloid mRNA contains a domain homologous to serine proteinase inhibitors.
    Ponte P, Gonzalez-DeWhitt P, Schilling J, Miller J, Hsu D, Greenberg B, Davis K, Wallace W, Lieberburg I, Fuller F.
    Nature; 1988 Feb 11; 331(6156):525-7. PubMed ID: 2893289
    [Abstract] [Full Text] [Related]

  • 19. Affinity and specificity of serine endopeptidase-protein inhibitor interactions. Empirical free energy calculations based on X-ray crystallographic structures.
    Krystek S, Stouch T, Novotny J.
    J Mol Biol; 1993 Dec 05; 234(3):661-79. PubMed ID: 8254666
    [Abstract] [Full Text] [Related]

  • 20. Homology of the amyloid beta protein precursor in monkey and human supports a primate model for beta amyloidosis in Alzheimer's disease.
    Podlisny MB, Tolan DR, Selkoe DJ.
    Am J Pathol; 1991 Jun 05; 138(6):1423-35. PubMed ID: 1905108
    [Abstract] [Full Text] [Related]

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