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Journal Abstract Search

188 related items for PubMed ID: 21262347

  • 1. Inhibition of thioredoxin reductase 1 by porphyrins and other small molecules identified by a high-throughput screening assay.
    Prast-Nielsen S, Dexheimer TS, Schultz L, Stafford WC, Cheng Q, Xu J, Jadhav A, Arnér ES, Simeonov A.
    Free Radic Biol Med; 2011 May 01; 50(9):1114-23. PubMed ID: 21262347
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  • 2. Substrate and inhibitor specificities differ between human cytosolic and mitochondrial thioredoxin reductases: Implications for development of specific inhibitors.
    Rackham O, Shearwood AM, Thyer R, McNamara E, Davies SM, Callus BA, Miranda-Vizuete A, Berners-Price SJ, Cheng Q, Arnér ES, Filipovska A.
    Free Radic Biol Med; 2011 Mar 15; 50(6):689-99. PubMed ID: 21172426
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  • 10. High levels of thioredoxin reductase 1 modulate drug-specific cytotoxic efficacy.
    Eriksson SE, Prast-Nielsen S, Flaberg E, Szekely L, Arnér ES.
    Free Radic Biol Med; 2009 Dec 01; 47(11):1661-71. PubMed ID: 19766715
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  • 11. Evaluation of N-acetyl-S-(p-chlorophenylcarbamoyl)cysteine as an irreversible inhibitor of mammalian thioredoxin reductase1.
    Chen W, Jiang Z, Lin N, Zheng Z, Chen Z, Zhang X, Guan X.
    J Enzyme Inhib Med Chem; 2016 Dec 01; 31(2):229-35. PubMed ID: 25778746
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  • 12. Sublethal concentrations of diverse gold compounds inhibit mammalian cytosolic thioredoxin reductase (TrxR1).
    Omata Y, Folan M, Shaw M, Messer RL, Lockwood PE, Hobbs D, Bouillaguet S, Sano H, Lewis JB, Wataha JC.
    Toxicol In Vitro; 2006 Sep 01; 20(6):882-90. PubMed ID: 16510263
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  • 13. Acrolein-induced activation of mitogen-activated protein kinase signaling is mediated by alkylation of thioredoxin reductase and thioredoxin 1.
    Randall MJ, Spiess PC, Hristova M, Hondal RJ, van der Vliet A.
    Redox Biol; 2013 Sep 01; 1(1):265-75. PubMed ID: 24024160
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  • 14. Menadione inhibits thioredoxin reductase 1 via arylation at the Sec498 residue and enhances both NADPH oxidation and superoxide production in Sec498 to Cys498 substitution.
    Sun S, Xu W, Zhang Y, Yang Y, Ma Q, Xu J.
    Free Radic Biol Med; 2021 Aug 20; 172():482-489. PubMed ID: 34186208
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  • 15. To inhibit TrxR1 is to inactivate STAT3-Inhibition of TrxR1 enzymatic function by STAT3 small molecule inhibitors.
    Busker S, Page B, Arnér ESJ.
    Redox Biol; 2020 Sep 20; 36():101646. PubMed ID: 32863208
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  • 16. Arsenic trioxide and auranofin inhibit selenoprotein synthesis: implications for chemotherapy for acute promyelocytic leukaemia.
    Talbot S, Nelson R, Self WT.
    Br J Pharmacol; 2008 Jul 20; 154(5):940-8. PubMed ID: 18587442
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  • 17. Thioredoxin Reductase Inhibition for Cancer Therapy.
    Gencheva R, Arnér ESJ.
    Annu Rev Pharmacol Toxicol; 2022 Jan 06; 62():177-196. PubMed ID: 34449246
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  • 19. Novel electrophilic amides amenable by the Ugi reaction perturb thioredoxin system via thioredoxin reductase 1 (TrxR1) inhibition: Identification of DVD-445 as a new lead compound for anticancer therapy.
    Jovanović M, Zhukovsky D, Podolski-Renić A, Domračeva I, Žalubovskis R, Senćanski M, Glišić S, Sharoyko V, Tennikova T, Dar'in D, Pešić M, Krasavin M.
    Eur J Med Chem; 2019 Nov 01; 181():111580. PubMed ID: 31400708
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  • 20. Thiophosphate and selenite conversely modulate cell death induced by glutathione depletion or cisplatin: effects related to activity and Sec contents of thioredoxin reductase.
    Peng X, Xu J, Arnér ES.
    Biochem J; 2012 Oct 01; 447(1):167-74. PubMed ID: 22784015
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