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Journal Abstract Search

351 related items for PubMed ID: 21266325

  • 1. Deletion of Lkb1 in pro-opiomelanocortin neurons impairs peripheral glucose homeostasis in mice.
    Claret M, Smith MA, Knauf C, Al-Qassab H, Woods A, Heslegrave A, Piipari K, Emmanuel JJ, Colom A, Valet P, Cani PD, Begum G, White A, Mucket P, Peters M, Mizuno K, Batterham RL, Giese KP, Ashworth A, Burcelin R, Ashford ML, Carling D, Withers DJ.
    Diabetes; 2011 Mar; 60(3):735-45. PubMed ID: 21266325
    [Abstract] [Full Text] [Related]

  • 2. AMPK is essential for energy homeostasis regulation and glucose sensing by POMC and AgRP neurons.
    Claret M, Smith MA, Batterham RL, Selman C, Choudhury AI, Fryer LG, Clements M, Al-Qassab H, Heffron H, Xu AW, Speakman JR, Barsh GS, Viollet B, Vaulont S, Ashford ML, Carling D, Withers DJ.
    J Clin Invest; 2007 Aug; 117(8):2325-36. PubMed ID: 17671657
    [Abstract] [Full Text] [Related]

  • 3. Deletion of liver kinase B1 in POMC neurons predisposes to diet-induced obesity.
    Wu Z, Han J, Xue J, Xi P, Wang H, He L, Wang Q, Liang H, Sun X, Tian D.
    Life Sci; 2020 Oct 01; 258():118204. PubMed ID: 32763296
    [Abstract] [Full Text] [Related]

  • 4. Ire1α in Pomc Neurons Is Required for Thermogenesis and Glycemia.
    Yao T, Deng Z, Gao Y, Sun J, Kong X, Huang Y, He Z, Xu Y, Chang Y, Yu KJ, Findley BG, Berglund ED, Wang RT, Guo H, Chen H, Li X, Kaufman RJ, Yan J, Liu T, Williams KW.
    Diabetes; 2017 Mar 01; 66(3):663-673. PubMed ID: 28028078
    [Abstract] [Full Text] [Related]

  • 5. Glucose regulates AMP-activated protein kinase activity and gene expression in clonal, hypothalamic neurons expressing proopiomelanocortin: additive effects of leptin or insulin.
    Cai F, Gyulkhandanyan AV, Wheeler MB, Belsham DD.
    J Endocrinol; 2007 Mar 01; 192(3):605-14. PubMed ID: 17332528
    [Abstract] [Full Text] [Related]

  • 6. Overexpression of Smad7 in hypothalamic POMC neurons disrupts glucose balance by attenuating central insulin signaling.
    Yuan F, Yin H, Deng Y, Jiao F, Jiang H, Niu Y, Chen S, Ying H, Zhai Q, Chen Y, Guo F.
    Mol Metab; 2020 Dec 01; 42():101084. PubMed ID: 32971298
    [Abstract] [Full Text] [Related]

  • 7. Phosphatidyl inositol 3-kinase signaling in hypothalamic proopiomelanocortin neurons contributes to the regulation of glucose homeostasis.
    Hill JW, Xu Y, Preitner F, Fukuda M, Cho YR, Luo J, Balthasar N, Coppari R, Cantley LC, Kahn BB, Zhao JJ, Elmquist JK.
    Endocrinology; 2009 Nov 01; 150(11):4874-82. PubMed ID: 19819947
    [Abstract] [Full Text] [Related]

  • 8. Gpr17 deficiency in POMC neurons ameliorates the metabolic derangements caused by long-term high-fat diet feeding.
    Reilly AM, Zhou S, Panigrahi SK, Yan S, Conley JM, Sheets PL, Wardlaw SL, Ren H.
    Nutr Diabetes; 2019 Oct 14; 9(1):29. PubMed ID: 31611548
    [Abstract] [Full Text] [Related]

  • 9. Enhanced Stat3 activation in POMC neurons provokes negative feedback inhibition of leptin and insulin signaling in obesity.
    Ernst MB, Wunderlich CM, Hess S, Paehler M, Mesaros A, Koralov SB, Kleinridders A, Husch A, Münzberg H, Hampel B, Alber J, Kloppenburg P, Brüning JC, Wunderlich FT.
    J Neurosci; 2009 Sep 16; 29(37):11582-93. PubMed ID: 19759305
    [Abstract] [Full Text] [Related]

  • 10. Intraventricular Injection of LKB1 Inhibits the Formation of Diet-Induced Obesity in Rats by Activating the AMPK-POMC Neurons-Sympathetic Nervous System Axis.
    Xi P, Du J, Liang H, Han J, Wu Z, Wang H, He L, Wang Q, Ge H, Li Y, Xue J, Tian D.
    Cell Physiol Biochem; 2018 Sep 16; 47(1):54-66. PubMed ID: 29763913
    [Abstract] [Full Text] [Related]

  • 11. LKB1 deletion with the RIP2.Cre transgene modifies pancreatic beta-cell morphology and enhances insulin secretion in vivo.
    Sun G, Tarasov AI, McGinty JA, French PM, McDonald A, Leclerc I, Rutter GA.
    Am J Physiol Endocrinol Metab; 2010 Jun 16; 298(6):E1261-73. PubMed ID: 20354156
    [Abstract] [Full Text] [Related]

  • 12. Ribosomal S6K1 in POMC and AgRP Neurons Regulates Glucose Homeostasis but Not Feeding Behavior in Mice.
    Smith MA, Katsouri L, Irvine EE, Hankir MK, Pedroni SM, Voshol PJ, Gordon MW, Choudhury AI, Woods A, Vidal-Puig A, Carling D, Withers DJ.
    Cell Rep; 2015 Apr 21; 11(3):335-43. PubMed ID: 25865886
    [Abstract] [Full Text] [Related]

  • 13. Cellular insulin resistance disrupts hypothalamic mHypoA-POMC/GFP neuronal signaling pathways.
    Nazarians-Armavil A, Chalmers JA, Lee CB, Ye W, Belsham DD.
    J Endocrinol; 2014 Jan 21; 220(1):13-24. PubMed ID: 24134870
    [Abstract] [Full Text] [Related]

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  • 15. Deletion of Protein Kinase C λ in POMC Neurons Predisposes to Diet-Induced Obesity.
    Dorfman MD, Krull JE, Scarlett JM, Guyenet SJ, Sajan MP, Damian V, Nguyen HT, Leitges M, Morton GJ, Farese RV, Schwartz MW, Thaler JP.
    Diabetes; 2017 Apr 21; 66(4):920-934. PubMed ID: 28073831
    [Abstract] [Full Text] [Related]

  • 16. The transcriptional regulator PRDM12 is critical for Pomc expression in the mouse hypothalamus and controlling food intake, adiposity, and body weight.
    Hael CE, Rojo D, Orquera DP, Low MJ, Rubinstein M.
    Mol Metab; 2020 Apr 21; 34():43-53. PubMed ID: 32180559
    [Abstract] [Full Text] [Related]

  • 17. PDK1 deficiency in POMC-expressing cells reveals FOXO1-dependent and -independent pathways in control of energy homeostasis and stress response.
    Belgardt BF, Husch A, Rother E, Ernst MB, Wunderlich FT, Hampel B, Klöckener T, Alessi D, Kloppenburg P, Brüning JC.
    Cell Metab; 2008 Apr 21; 7(4):291-301. PubMed ID: 18396135
    [Abstract] [Full Text] [Related]

  • 18. Direct leptin action on POMC neurons regulates glucose homeostasis and hepatic insulin sensitivity in mice.
    Berglund ED, Vianna CR, Donato J, Kim MH, Chuang JC, Lee CE, Lauzon DA, Lin P, Brule LJ, Scott MM, Coppari R, Elmquist JK.
    J Clin Invest; 2012 Mar 21; 122(3):1000-9. PubMed ID: 22326958
    [Abstract] [Full Text] [Related]

  • 19. Leptin receptor signaling in POMC neurons is required for normal body weight homeostasis.
    Balthasar N, Coppari R, McMinn J, Liu SM, Lee CE, Tang V, Kenny CD, McGovern RA, Chua SC, Elmquist JK, Lowell BB.
    Neuron; 2004 Jun 24; 42(6):983-91. PubMed ID: 15207242
    [Abstract] [Full Text] [Related]

  • 20. LKB1 on POMC neurons affect the formation of diet-induced obesity by regulating the expression of HDAC1.
    Zhang Y, Wu Z, Xi P, Wang H, Zhu W, Tian D.
    Genes Genomics; 2022 Apr 24; 44(4):467-475. PubMed ID: 35072921
    [Abstract] [Full Text] [Related]

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