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Journal Abstract Search

206 related items for PubMed ID: 21273081

  • 1. A competition assay to identify amyloidogenesis inhibitors by monitoring the fluorescence emitted by the covalent attachment of a stilbene derivative to transthyretin.
    Choi S, Kelly JW.
    Bioorg Med Chem; 2011 Feb 15; 19(4):1505-14. PubMed ID: 21273081
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  • 2. A substructure combination strategy to create potent and selective transthyretin kinetic stabilizers that prevent amyloidogenesis and cytotoxicity.
    Choi S, Reixach N, Connelly S, Johnson SM, Wilson IA, Kelly JW.
    J Am Chem Soc; 2010 Feb 03; 132(4):1359-70. PubMed ID: 20043671
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  • 4. Aromatic sulfonyl fluorides covalently kinetically stabilize transthyretin to prevent amyloidogenesis while affording a fluorescent conjugate.
    Grimster NP, Connelly S, Baranczak A, Dong J, Krasnova LB, Sharpless KB, Powers ET, Wilson IA, Kelly JW.
    J Am Chem Soc; 2013 Apr 17; 135(15):5656-68. PubMed ID: 23350654
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  • 7. Kinetic stabilization of the native state by protein engineering: implications for inhibition of transthyretin amyloidogenesis.
    Foss TR, Kelker MS, Wiseman RL, Wilson IA, Kelly JW.
    J Mol Biol; 2005 Apr 08; 347(4):841-54. PubMed ID: 15769474
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  • 11. Stilbene Boronic Acids Form a Covalent Bond with Human Transthyretin and Inhibit Its Aggregation.
    Smith TP, Windsor IW, Forest KT, Raines RT.
    J Med Chem; 2017 Sep 28; 60(18):7820-7834. PubMed ID: 28920684
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  • 14. Synthesis and characterization of potent bivalent amyloidosis inhibitors that bind prior to transthyretin tetramerization.
    Green NS, Palaninathan SK, Sacchettini JC, Kelly JW.
    J Am Chem Soc; 2003 Nov 05; 125(44):13404-14. PubMed ID: 14583036
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  • 15. The crystal structure of transthyretin in complex with diethylstilbestrol: a promising template for the design of amyloid inhibitors.
    Morais-de-Sá E, Pereira PJ, Saraiva MJ, Damas AM.
    J Biol Chem; 2004 Dec 17; 279(51):53483-90. PubMed ID: 15469931
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  • 17. Kinetic stabilization of an oligomeric protein by a single ligand binding event.
    Wiseman RL, Johnson SM, Kelker MS, Foss T, Wilson IA, Kelly JW.
    J Am Chem Soc; 2005 Apr 20; 127(15):5540-51. PubMed ID: 15826192
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  • 18. TTR fibril formation inhibitors: is there a SAR?
    Nencetti S, Orlandini E.
    Curr Med Chem; 2012 Apr 20; 19(15):2356-79. PubMed ID: 22471984
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  • 20. Transthyretin aggregation under partially denaturing conditions is a downhill polymerization.
    Hurshman AR, White JT, Powers ET, Kelly JW.
    Biochemistry; 2004 Jun 15; 43(23):7365-81. PubMed ID: 15182180
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