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Journal Abstract Search

213 related items for PubMed ID: 21282428

  • 1. Selective inhibitors of methionyl-tRNA synthetase have potent activity against Trypanosoma brucei Infection in Mice.
    Shibata S, Gillespie JR, Kelley AM, Napuli AJ, Zhang Z, Kovzun KV, Pefley RM, Lam J, Zucker FH, Van Voorhis WC, Merritt EA, Hol WG, Verlinde CL, Fan E, Buckner FS.
    Antimicrob Agents Chemother; 2011 May; 55(5):1982-9. PubMed ID: 21282428
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  • 2. Identification of potent inhibitors of the Trypanosoma brucei methionyl-tRNA synthetase via high-throughput orthogonal screening.
    Pedró-Rosa L, Buckner FS, Ranade RM, Eberhart C, Madoux F, Gillespie JR, Koh CY, Brown S, Lohse J, Verlinde CL, Fan E, Bannister T, Scampavia L, Hol WG, Spicer T, Hodder P.
    J Biomol Screen; 2015 Jan; 20(1):122-30. PubMed ID: 25163684
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  • 4. Structure-guided design of novel Trypanosoma brucei Methionyl-tRNA synthetase inhibitors.
    Huang W, Zhang Z, Barros-Álvarez X, Koh CY, Ranade RM, Gillespie JR, Creason SA, Shibata S, Verlinde CLMJ, Hol WGJ, Buckner FS, Fan E.
    Eur J Med Chem; 2016 Nov 29; 124():1081-1092. PubMed ID: 27788467
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  • 9. Structures of Trypanosoma brucei methionyl-tRNA synthetase with urea-based inhibitors provide guidance for drug design against sleeping sickness.
    Koh CY, Kim JE, Wetzel AB, de van der Schueren WJ, Shibata S, Ranade RM, Liu J, Zhang Z, Gillespie JR, Buckner FS, Verlinde CL, Fan E, Hol WG.
    PLoS Negl Trop Dis; 2014 Apr 29; 8(4):e2775. PubMed ID: 24743796
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  • 11. Inhibition of isoleucyl-tRNA synthetase as a potential treatment for human African Trypanosomiasis.
    Cestari I, Stuart K.
    J Biol Chem; 2013 May 17; 288(20):14256-14263. PubMed ID: 23548908
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  • 12. Chalcone, acyl hydrazide, and related amides kill cultured Trypanosoma brucei brucei.
    Troeberg L, Chen X, Flaherty TM, Morty RE, Cheng M, Hua H, Springer C, McKerrow JH, Kenyon GL, Lonsdale-Eccles JD, Coetzer TH, Cohen FE.
    Mol Med; 2000 Aug 17; 6(8):660-9. PubMed ID: 11055585
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  • 13. Design, synthesis, and structure-activity relationship of Trypanosoma brucei leucyl-tRNA synthetase inhibitors as antitrypanosomal agents.
    Ding D, Meng Q, Gao G, Zhao Y, Wang Q, Nare B, Jacobs R, Rock F, Alley MR, Plattner JJ, Chen G, Li D, Zhou H.
    J Med Chem; 2011 Mar 10; 54(5):1276-87. PubMed ID: 21322634
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  • 14. Orally Active and Selective Tubulin Inhibitors as Anti-Trypanosome Agents.
    Nanavaty V, Lama R, Sandhu R, Zhong B, Kulman D, Bobba V, Zhao A, Li B, Su B.
    PLoS One; 2016 Mar 10; 11(1):e0146289. PubMed ID: 26771307
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  • 20. Synthesis and tripanocidal activity of ferrocenyl and benzyl diamines against Trypanosoma brucei and Trypanosoma cruzi.
    Velásquez AM, Francisco AI, Kohatsu AA, Silva FA, Rodrigues DF, Teixeira RG, Chiari BG, de Almeida MG, Isaac VL, Vargas MD, Cicarelli RM.
    Bioorg Med Chem Lett; 2014 Apr 01; 24(7):1707-10. PubMed ID: 24630563
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