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186 related items for PubMed ID: 21282562

  • 1. Decreased cGMP level contributes to increased contraction in arteries from hypertensive rats: role of phosphodiesterase 1.
    Giachini FR, Lima VV, Carneiro FS, Tostes RC, Webb RC.
    Hypertension; 2011 Mar; 57(3):655-63. PubMed ID: 21282562
    [Abstract] [Full Text] [Related]

  • 2. Phosphodiesterase 5 inhibition ameliorates angiotensin II-dependent hypertension and renal vascular dysfunction.
    Thieme M, Sivritas SH, Mergia E, Potthoff SA, Yang G, Hering L, Grave K, Hoch H, Rump LC, Stegbauer J.
    Am J Physiol Renal Physiol; 2017 Mar 01; 312(3):F474-F481. PubMed ID: 28052870
    [Abstract] [Full Text] [Related]

  • 3. Angiotensin II-mediated hypertension impairs nitric oxide-induced NKCC2 inhibition in thick ascending limbs.
    Ramseyer VD, Ortiz PA, Carretero OA, Garvin JL.
    Am J Physiol Renal Physiol; 2016 Apr 15; 310(8):F748-F754. PubMed ID: 26887831
    [Abstract] [Full Text] [Related]

  • 4. Upregulation of phosphodiesterase 1A1 expression is associated with the development of nitrate tolerance.
    Kim D, Rybalkin SD, Pi X, Wang Y, Zhang C, Munzel T, Beavo JA, Berk BC, Yan C.
    Circulation; 2001 Nov 06; 104(19):2338-43. PubMed ID: 11696475
    [Abstract] [Full Text] [Related]

  • 5. The effect of sildenafil on the altered thoracic aorta smooth muscle responses in rat pre-eclampsia model.
    Turgut NH, Temiz TK, Bagcivan I, Turgut B, Gulturk S, Karadas B.
    Eur J Pharmacol; 2008 Jul 28; 589(1-3):180-7. PubMed ID: 18538317
    [Abstract] [Full Text] [Related]

  • 6. Effects of phosphodiesterase inhibitors on the contractile responses of isolated human seminal vesicle tissue to adrenergic stimulation.
    Uckert S, Bazrafshan S, Sonnenberg JE, Kuczyk MA.
    J Sex Med; 2009 Feb 28; 6(2):408-14. PubMed ID: 19040619
    [Abstract] [Full Text] [Related]

  • 7. Roles of cGMP-dependent protein kinase I (cGKI) and PDE5 in the regulation of Ang II-induced cardiac hypertrophy and fibrosis.
    Patrucco E, Domes K, Sbroggió M, Blaich A, Schlossmann J, Desch M, Rybalkin SD, Beavo JA, Lukowski R, Hofmann F.
    Proc Natl Acad Sci U S A; 2014 Sep 02; 111(35):12925-9. PubMed ID: 25139994
    [Abstract] [Full Text] [Related]

  • 8. Novel nitric oxide synthase--dependent mechanism of vasorelaxation in small arteries from hypertensive rats.
    Kang KT, Sullivan JC, Sasser JM, Imig JD, Pollock JS.
    Hypertension; 2007 Apr 02; 49(4):893-901. PubMed ID: 17309950
    [Abstract] [Full Text] [Related]

  • 9. Sildenafil attenuates placental ischemia-induced hypertension.
    George EM, Palei AC, Dent EA, Granger JP.
    Am J Physiol Regul Integr Comp Physiol; 2013 Aug 15; 305(4):R397-403. PubMed ID: 23785075
    [Abstract] [Full Text] [Related]

  • 10. Tissue distribution of phosphodiesterase families and the effects of sildenafil on tissue cyclic nucleotides, platelet function, and the contractile responses of trabeculae carneae and aortic rings in vitro.
    Wallis RM, Corbin JD, Francis SH, Ellis P.
    Am J Cardiol; 1999 Mar 04; 83(5A):3C-12C. PubMed ID: 10078537
    [Abstract] [Full Text] [Related]

  • 11. Nebivolol potentiates the efficacy of PDE5 inhibitors to relax corpus cavernosum and penile arteries from diabetic patients by enhancing the NO/cGMP pathway.
    Martínez-Salamanca JI, La Fuente JM, Cardoso J, Fernández A, Cuevas P, Wright HM, Angulo J.
    J Sex Med; 2014 May 04; 11(5):1182-92. PubMed ID: 24877179
    [Abstract] [Full Text] [Related]

  • 12. A novel PDE1A coupled to M2AChR at plasma membranes from bovine tracheal smooth muscle.
    Mastromatteo-Alberga P, Placeres-Uray F, Alfonzo-González MA, Alfonzo RG, Becemberg IL, Alfonzo MJ.
    J Recept Signal Transduct Res; 2016 May 04; 36(3):278-87. PubMed ID: 26513204
    [Abstract] [Full Text] [Related]

  • 13. Reduced vascular responses to soluble guanylyl cyclase but increased sensitivity to sildenafil in female rats with type 2 diabetes.
    Goulopoulou S, Hannan JL, Matsumoto T, Ogbi S, Ergul A, Webb RC.
    Am J Physiol Heart Circ Physiol; 2015 Jul 15; 309(2):H297-304. PubMed ID: 25957216
    [Abstract] [Full Text] [Related]

  • 14. Phosphodiesterase 5 and effects of sildenafil on cerebral arteries of man and guinea pig.
    Kruuse C, Khurana TS, Rybalkin SD, Birk S, Engel U, Edvinsson L, Olesen J.
    Eur J Pharmacol; 2005 Oct 03; 521(1-3):105-14. PubMed ID: 16182282
    [Abstract] [Full Text] [Related]

  • 15. Beneficial Morphofunctional Changes Promoted by Sildenafil in Resistance Vessels in the Angiotensin II-Induced Hypertension Model.
    Dias AT, Leal MAS, Zanardo TC, Alves GM, Porto ML, Nogueira BV, Gava AL, Campagnaro BP, Pereira TMC, Meyrelles SS, Campos-Toimil M, Vasquez EC.
    Curr Pharm Biotechnol; 2018 Oct 03; 19(6):483-494. PubMed ID: 29938618
    [Abstract] [Full Text] [Related]

  • 16. Sildenafil reduces L-NAME-induced severe hypertension and worsening of myocardial ischaemia-reperfusion damage in the rat.
    Rossoni G, Manfredi B, De Gennaro Colonna V, Berti M, Guazzi M, Berti F.
    Br J Pharmacol; 2007 Mar 03; 150(5):567-76. PubMed ID: 17245365
    [Abstract] [Full Text] [Related]

  • 17. Anti-platelet therapy with clopidogrel prevents endothelial dysfunction and vascular remodeling in aortas from hypertensive rats.
    Giachini FR, Leite R, Osmond DA, Lima VV, Inscho EW, Webb RC, Tostes RC.
    PLoS One; 2014 Mar 03; 9(3):e91890. PubMed ID: 24638017
    [Abstract] [Full Text] [Related]

  • 18. Antihypertensive therapy increases tetrahydrobiopterin levels and NO/cGMP signaling in small arteries of angiotensin II-infused hypertensive rats.
    Kang KT, Sullivan JC, Spradley FT, d'Uscio LV, Katusic ZS, Pollock JS.
    Am J Physiol Heart Circ Physiol; 2011 Mar 03; 300(3):H718-24. PubMed ID: 21148769
    [Abstract] [Full Text] [Related]

  • 19. Phosphodiesterase 5 (PDE5) inhibition, ANP and NO rapidly reduce epididymal duct contractions, but long-term PDE5 inhibition in vivo does not.
    Mietens A, Tasch S, Feuerstacke C, Eichner G, Volkmann J, Schermuly RT, Grimminger F, Müller D, Middendorff R.
    Mol Cell Endocrinol; 2012 Feb 26; 349(2):145-53. PubMed ID: 21996373
    [Abstract] [Full Text] [Related]

  • 20. PDE1 or PDE5 inhibition augments NO-dependent hypoxic constriction of porcine coronary artery via elevating inosine 3',5'-cyclic monophosphate level.
    Nan Y, Zeng X, Jin Z, Li N, Chen Z, Chen J, Wang D, Wang Y, Lin Z, Ying L.
    J Cell Mol Med; 2020 Dec 26; 24(24):14514-14524. PubMed ID: 33169529
    [Abstract] [Full Text] [Related]

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