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Journal Abstract Search

389 related items for PubMed ID: 21289076

  • 1. Reevaluation of the microsomal metabolism of montelukast: major contribution by CYP2C8 at clinically relevant concentrations.
    Filppula AM, Laitila J, Neuvonen PJ, Backman JT.
    Drug Metab Dispos; 2011 May; 39(5):904-11. PubMed ID: 21289076
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  • 2. The role of human CYP2C8 and CYP2C9 variants in pioglitazone metabolism in vitro.
    Muschler E, Lal J, Jetter A, Rattay A, Zanger U, Zadoyan G, Fuhr U, Kirchheiner J.
    Basic Clin Pharmacol Toxicol; 2009 Dec; 105(6):374-9. PubMed ID: 19614891
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  • 3. Gemfibrozil markedly increases the plasma concentrations of montelukast: a previously unrecognized role for CYP2C8 in the metabolism of montelukast.
    Karonen T, Filppula A, Laitila J, Niemi M, Neuvonen PJ, Backman JT.
    Clin Pharmacol Ther; 2010 Aug; 88(2):223-30. PubMed ID: 20592724
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  • 4. Confirmation that cytochrome P450 2C8 (CYP2C8) plays a minor role in (S)-(+)- and (R)-(-)-ibuprofen hydroxylation in vitro.
    Chang SY, Li W, Traeger SC, Wang B, Cui D, Zhang H, Wen B, Rodrigues AD.
    Drug Metab Dispos; 2008 Dec; 36(12):2513-22. PubMed ID: 18787056
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  • 5. Selective inhibition of human cytochrome P4502C8 by montelukast.
    Walsky RL, Obach RS, Gaman EA, Gleeson JP, Proctor WR.
    Drug Metab Dispos; 2005 Mar; 33(3):413-8. PubMed ID: 15608135
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  • 10. In vitro metabolism of the calmodulin antagonist DY-9760e (3-[2-[4-(3-chloro-2-methylphenyl)-1-piperazinyl]ethyl]-5,6-dimethoxy-1-(4-imidazolylmethyl)-1H-indazole dihydrochloride 3.5 hydrate) by human liver microsomes: involvement of cytochromes p450 in atypical kinetics and potential drug interactions.
    Tachibana S, Fujimaki Y, Yokoyama H, Okazaki O, Sudo K.
    Drug Metab Dispos; 2005 Nov; 33(11):1628-36. PubMed ID: 16049129
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  • 12. Involvement of CYP3A4, CYP2C8, and CYP2D6 in the metabolism of (R)- and (S)-methadone in vitro.
    Wang JS, DeVane CL.
    Drug Metab Dispos; 2003 Jun; 31(6):742-7. PubMed ID: 12756206
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  • 14. Human CYP2C19 is a major omeprazole 5-hydroxylase, as demonstrated with recombinant cytochrome P450 enzymes.
    Karam WG, Goldstein JA, Lasker JM, Ghanayem BI.
    Drug Metab Dispos; 1996 Oct; 24(10):1081-7. PubMed ID: 8894508
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  • 15. Inhibitory effect of glyburide on human cytochrome p450 isoforms in human liver microsomes.
    Kim KA, Park JY.
    Drug Metab Dispos; 2003 Sep; 31(9):1090-2. PubMed ID: 12920163
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  • 17. Interaction of cisapride with the human cytochrome P450 system: metabolism and inhibition studies.
    Desta Z, Soukhova N, Mahal SK, Flockhart DA.
    Drug Metab Dispos; 2000 Jul; 28(7):789-800. PubMed ID: 10859153
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  • 20. Oxidation of 1,8-cineole, the monoterpene cyclic ether originated from eucalyptus polybractea, by cytochrome P450 3A enzymes in rat and human liver microsomes.
    Miyazawa M, Shindo M, Shimada T.
    Drug Metab Dispos; 2001 Feb; 29(2):200-5. PubMed ID: 11159812
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