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Journal Abstract Search

353 related items for PubMed ID: 21321191

  • 1. Activation of the NF-kappaB pathway by adeno-associated virus (AAV) vectors and its implications in immune response and gene therapy.
    Jayandharan GR, Aslanidi G, Martino AT, Jahn SC, Perrin GQ, Herzog RW, Srivastava A.
    Proc Natl Acad Sci U S A; 2011 Mar 01; 108(9):3743-8. PubMed ID: 21321191
    [Abstract] [Full Text] [Related]

  • 2. Synergistic inhibition of PARP-1 and NF-κB signaling downregulates immune response against recombinant AAV2 vectors during hepatic gene therapy.
    Hareendran S, Ramakrishna B, Jayandharan GR.
    Eur J Immunol; 2016 Jan 01; 46(1):154-66. PubMed ID: 26443873
    [Abstract] [Full Text] [Related]

  • 3. An adeno-associated virus-based intracellular sensor of pathological nuclear factor-κB activation for disease-inducible gene transfer.
    Chtarto A, Bockstael O, Gebara E, Vermoesen K, Melas C, Pythoud C, Levivier M, De Witte O, Luthi-Carter R, Clinkers R, Tenenbaum L.
    PLoS One; 2013 Jan 01; 8(1):e53156. PubMed ID: 23301037
    [Abstract] [Full Text] [Related]

  • 4. Double-stranded RNA innate immune response activation from long-term adeno-associated virus vector transduction.
    Shao W, Earley LF, Chai Z, Chen X, Sun J, He T, Deng M, Hirsch ML, Ting J, Samulski RJ, Li C.
    JCI Insight; 2018 Jun 21; 3(12):. PubMed ID: 29925692
    [Abstract] [Full Text] [Related]

  • 5. Inhibition of the IKK/NF-κB pathway by AAV gene transfer improves muscle regeneration in older mdx mice.
    Tang Y, Reay DP, Salay MN, Mi MY, Clemens PR, Guttridge DC, Robbins PD, Huard J, Wang B.
    Gene Ther; 2010 Dec 21; 17(12):1476-83. PubMed ID: 20720575
    [Abstract] [Full Text] [Related]

  • 6. Gene transfer into hepatocytes mediated by helper virus-free HSV/AAV hybrid vectors.
    Fraefel C, Jacoby DR, Lage C, Hilderbrand H, Chou JY, Alt FW, Breakefield XO, Majzoub JA.
    Mol Med; 1997 Dec 21; 3(12):813-25. PubMed ID: 9440115
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  • 7. Immune responses to AAV in clinical trials.
    Mingozzi F, High KA.
    Curr Gene Ther; 2007 Oct 21; 7(5):316-24. PubMed ID: 17979678
    [Abstract] [Full Text] [Related]

  • 8. Enhanced transgene expression from recombinant single-stranded D-sequence-substituted adeno-associated virus vectors in human cell lines in vitro and in murine hepatocytes in vivo.
    Ling C, Wang Y, Lu Y, Wang L, Jayandharan GR, Aslanidi GV, Li B, Cheng B, Ma W, Lentz T, Ling C, Xiao X, Samulski RJ, Muzyczka N, Srivastava A.
    J Virol; 2015 Jan 15; 89(2):952-61. PubMed ID: 25355884
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  • 12. Herpes simplex virus type 1/adeno-associated virus hybrid vectors mediate site-specific integration at the adeno-associated virus preintegration site, AAVS1, on human chromosome 19.
    Heister T, Heid I, Ackermann M, Fraefel C.
    J Virol; 2002 Jul 15; 76(14):7163-73. PubMed ID: 12072516
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  • 15. Ocular Inflammatory Response to Intravitreal Injection of Adeno-Associated Virus Vector: Relative Contribution of Genome and Capsid.
    Timmers AM, Newmark JA, Turunen HT, Farivar T, Liu J, Song C, Ye GJ, Pennock S, Gaskin C, Knop DR, Shearman MS.
    Hum Gene Ther; 2020 Jan 15; 31(1-2):80-89. PubMed ID: 31544533
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  • 16. Transient and intensive pharmacological immunosuppression fails to improve AAV-based liver gene transfer in non-human primates.
    Unzu C, Hervás-Stubbs S, Sampedro A, Mauleón I, Mancheño U, Alfaro C, de Salamanca RE, Benito A, Beattie SG, Petry H, Prieto J, Melero I, Fontanellas A.
    J Transl Med; 2012 Jun 15; 10():122. PubMed ID: 22704060
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  • 17. Complement is an essential component of the immune response to adeno-associated virus vectors.
    Zaiss AK, Cotter MJ, White LR, Clark SA, Wong NC, Holers VM, Bartlett JS, Muruve DA.
    J Virol; 2008 Mar 15; 82(6):2727-40. PubMed ID: 18199646
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  • 18. Inhibition of NF-kappaB activation in combination with bcl-2 expression allows for persistence of first-generation adenovirus vectors in the mouse liver.
    Lieber A, He CY, Meuse L, Himeda C, Wilson C, Kay MA.
    J Virol; 1998 Nov 15; 72(11):9267-77. PubMed ID: 9765474
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  • 19. Inflammation promotes the loss of adeno-associated virus-mediated transgene expression in mouse liver.
    Breous E, Somanathan S, Bell P, Wilson JM.
    Gastroenterology; 2011 Jul 15; 141(1):348-57, 357.e1-3. PubMed ID: 21640112
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  • 20. Herpes simplex virus type 1/adeno-associated virus rep(+) hybrid amplicon vector improves the stability of transgene expression in human cells by site-specific integration.
    Wang Y, Camp SM, Niwano M, Shen X, Bakowska JC, Breakefield XO, Allen PD.
    J Virol; 2002 Jul 15; 76(14):7150-62. PubMed ID: 12072515
    [Abstract] [Full Text] [Related]

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