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733 related items for PubMed ID: 21328456

  • 1. Essential roles of the nitric oxide (no)/cGMP/protein kinase G type-Iα (PKG-Iα) signaling pathway and the atrial natriuretic peptide (ANP)/cGMP/PKG-Iα autocrine loop in promoting proliferation and cell survival of OP9 bone marrow stromal cells.
    Wong JC, Fiscus RR.
    J Cell Biochem; 2011 Mar; 112(3):829-39. PubMed ID: 21328456
    [Abstract] [Full Text] [Related]

  • 2. Pancreatic-β-cell survival and proliferation are promoted by protein kinase G type Iα and downstream regulation of AKT/FOXO1.
    Wong JC, Vo V, Gorjala P, Fiscus RR.
    Diab Vasc Dis Res; 2017 Sep; 14(5):434-449. PubMed ID: 28631500
    [Abstract] [Full Text] [Related]

  • 3. Cyclic GMP/protein kinase G type-Iα (PKG-Iα) signaling pathway promotes CREB phosphorylation and maintains higher c-IAP1, livin, survivin, and Mcl-1 expression and the inhibition of PKG-Iα kinase activity synergizes with cisplatin in non-small cell lung cancer cells.
    Wong JC, Bathina M, Fiscus RR.
    J Cell Biochem; 2012 Nov; 113(11):3587-98. PubMed ID: 22740515
    [Abstract] [Full Text] [Related]

  • 4. Protein kinase G type Ialpha activity in human ovarian cancer cells significantly contributes to enhanced Src activation and DNA synthesis/cell proliferation.
    Leung EL, Wong JC, Johlfs MG, Tsang BK, Fiscus RR.
    Mol Cancer Res; 2010 Apr; 8(4):578-91. PubMed ID: 20371672
    [Abstract] [Full Text] [Related]

  • 5. Protein kinase G type-Ialpha phosphorylates the apoptosis-regulating protein Bad at serine 155 and protects against apoptosis in N1E-115 cells.
    Johlfs MG, Fiscus RR.
    Neurochem Int; 2010 Mar; 56(4):546-53. PubMed ID: 20043968
    [Abstract] [Full Text] [Related]

  • 6. Protein kinase G activity prevents pathological-level nitric oxide-induced apoptosis and promotes DNA synthesis/cell proliferation in vascular smooth muscle cells.
    Wong JC, Fiscus RR.
    Cardiovasc Pathol; 2010 Mar; 19(6):e221-31. PubMed ID: 20060325
    [Abstract] [Full Text] [Related]

  • 7. Feedback control through cGMP-dependent protein kinase contributes to differential regulation and compartmentation of cGMP in rat cardiac myocytes.
    Castro LR, Schittl J, Fischmeister R.
    Circ Res; 2010 Nov 12; 107(10):1232-40. PubMed ID: 20847310
    [Abstract] [Full Text] [Related]

  • 8. Nitric oxide regulates AKT phosphorylation and nuclear translocation in cultured retinal cells.
    Mejía-García TA, Portugal CC, Encarnação TG, Prado MA, Paes-de-Carvalho R.
    Cell Signal; 2013 Dec 12; 25(12):2424-39. PubMed ID: 23958999
    [Abstract] [Full Text] [Related]

  • 9. Nitric-oxide-dependent activation of pig oocytes: the role of the cGMP-signalling pathway.
    Petr J, Rajmon R, Chmelíková E, Tománek M, Lánská V, Pribánová M, Jílek F.
    Zygote; 2006 Feb 12; 14(1):9-16. PubMed ID: 16700970
    [Abstract] [Full Text] [Related]

  • 10. Regulation of p53 and suppression of apoptosis by the soluble guanylyl cyclase/cGMP pathway in human ovarian cancer cells.
    Fraser M, Chan SL, Chan SS, Fiscus RR, Tsang BK.
    Oncogene; 2006 Apr 06; 25(15):2203-12. PubMed ID: 16288207
    [Abstract] [Full Text] [Related]

  • 11. Role of cGMP-PKG signaling in the protection of neonatal rat cardiac myocytes subjected to simulated ischemia/reoxygenation.
    Gorbe A, Giricz Z, Szunyog A, Csont T, Burley DS, Baxter GF, Ferdinandy P.
    Basic Res Cardiol; 2010 Sep 06; 105(5):643-50. PubMed ID: 20349314
    [Abstract] [Full Text] [Related]

  • 12. Guanylyl cyclase inhibitors NS2028 and ODQ and protein kinase G (PKG) inhibitor KT5823 trigger apoptotic DNA fragmentation in immortalized uterine epithelial cells: anti-apoptotic effects of basal cGMP/PKG.
    Chan SL, Fiscus RR.
    Mol Hum Reprod; 2003 Dec 06; 9(12):775-83. PubMed ID: 14614039
    [Abstract] [Full Text] [Related]

  • 13. Atrial natriuretic peptide and nitric oxide signaling antagonizes vasopressin-mediated water permeability in inner medullary collecting duct cells.
    Klokkers J, Langehanenberg P, Kemper B, Kosmeier S, von Bally G, Riethmüller C, Wunder F, Sindic A, Pavenstädt H, Schlatter E, Edemir B.
    Am J Physiol Renal Physiol; 2009 Sep 06; 297(3):F693-703. PubMed ID: 19570884
    [Abstract] [Full Text] [Related]

  • 14. The bradykinin-cGMP-PKG pathway augments insulin sensitivity via upregulation of MAPK phosphatase-5 and inhibition of JNK.
    Frigolet ME, Thomas G, Beard K, Lu H, Liu L, Fantus IG.
    Am J Physiol Endocrinol Metab; 2017 Sep 01; 313(3):E321-E334. PubMed ID: 28679626
    [Abstract] [Full Text] [Related]

  • 15. The ANP-cGMP-protein kinase G pathway induces a phagocytic phenotype but decreases inflammatory gene expression in microglial cells.
    Borán MS, Baltrons MA, García A.
    Glia; 2008 Mar 01; 56(4):394-411. PubMed ID: 18186083
    [Abstract] [Full Text] [Related]

  • 16. Icariin stimulates the osteogenic differentiation of rat bone marrow stromal cells via activating the PI3K-AKT-eNOS-NO-cGMP-PKG.
    Zhai YK, Guo XY, Ge BF, Zhen P, Ma XN, Zhou J, Ma HP, Xian CJ, Chen KM.
    Bone; 2014 Sep 01; 66():189-98. PubMed ID: 24956021
    [Abstract] [Full Text] [Related]

  • 17. Cyclic guanosine monophosphate and the dependent protein kinase regulate lymphatic contractility in rat thoracic duct.
    Gasheva OY, Gashev AA, Zawieja DC.
    J Physiol; 2013 Sep 15; 591(18):4549-65. PubMed ID: 23836689
    [Abstract] [Full Text] [Related]

  • 18. Involvement of cyclic GMP and protein kinase G in the regulation of apoptosis and survival in neural cells.
    Fiscus RR.
    Neurosignals; 2002 Sep 15; 11(4):175-90. PubMed ID: 12393944
    [Abstract] [Full Text] [Related]

  • 19. Pro-survival effects of 17β-estradiol on osteocytes are mediated by nitric oxide/cGMP via differential actions of cGMP-dependent protein kinases I and II.
    Marathe N, Rangaswami H, Zhuang S, Boss GR, Pilz RB.
    J Biol Chem; 2012 Jan 06; 287(2):978-88. PubMed ID: 22117068
    [Abstract] [Full Text] [Related]

  • 20. Sp1 transcription factor as a molecular target for nitric oxide-- and cyclic nucleotide--mediated suppression of cGMP-dependent protein kinase-Ialpha expression in vascular smooth muscle cells.
    Sellak H, Yang X, Cao X, Cornwell T, Soff GA, Lincoln T.
    Circ Res; 2002 Mar 08; 90(4):405-12. PubMed ID: 11884369
    [Abstract] [Full Text] [Related]

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