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304 related items for PubMed ID: 21330634

  • 1. Chemopreventative potential of the cruciferous vegetable constituent phenethyl isothiocyanate in a mouse model of prostate cancer.
    Powolny AA, Bommareddy A, Hahm ER, Normolle DP, Beumer JH, Nelson JB, Singh SV.
    J Natl Cancer Inst; 2011 Apr 06; 103(7):571-84. PubMed ID: 21330634
    [Abstract] [Full Text] [Related]

  • 2. Biomarkers of phenethyl isothiocyanate-mediated mammary cancer chemoprevention in a clinically relevant mouse model.
    Singh SV, Kim SH, Sehrawat A, Arlotti JA, Hahm ER, Sakao K, Beumer JH, Jankowitz RC, Chandra-Kuntal K, Lee J, Powolny AA, Dhir R.
    J Natl Cancer Inst; 2012 Aug 22; 104(16):1228-39. PubMed ID: 22859850
    [Abstract] [Full Text] [Related]

  • 3. Inhibition of Glycolysis in Prostate Cancer Chemoprevention by Phenethyl Isothiocyanate.
    Singh KB, Hahm ER, Rigatti LH, Normolle DP, Yuan JM, Singh SV.
    Cancer Prev Res (Phila); 2018 Jun 22; 11(6):337-346. PubMed ID: 29545400
    [Abstract] [Full Text] [Related]

  • 4. Murine prostate cancer inhibition by dietary phytochemicals--curcumin and phenyethylisothiocyanate.
    Barve A, Khor TO, Hao X, Keum YS, Yang CS, Reddy B, Kong AN.
    Pharm Res; 2008 Sep 22; 25(9):2181-9. PubMed ID: 18437538
    [Abstract] [Full Text] [Related]

  • 5. Fatty Acid Synthesis Intermediates Represent Novel Noninvasive Biomarkers of Prostate Cancer Chemoprevention by Phenethyl Isothiocyanate.
    Singh KB, Singh SV.
    Cancer Prev Res (Phila); 2017 May 22; 10(5):279-289. PubMed ID: 28292742
    [Abstract] [Full Text] [Related]

  • 6. Phenethyl isothiocyanate and sulforaphane and their N-acetylcysteine conjugates inhibit malignant progression of lung adenomas induced by tobacco carcinogens in A/J mice.
    Conaway CC, Wang CX, Pittman B, Yang YM, Schwartz JE, Tian D, McIntee EJ, Hecht SS, Chung FL.
    Cancer Res; 2005 Sep 15; 65(18):8548-57. PubMed ID: 16166336
    [Abstract] [Full Text] [Related]

  • 7. CXCR4 is a novel target of cancer chemopreventative isothiocyanates in prostate cancer cells.
    Sakao K, Vyas AR, Chinni SR, Amjad AI, Parikh R, Singh SV.
    Cancer Prev Res (Phila); 2015 May 15; 8(5):365-74. PubMed ID: 25712054
    [Abstract] [Full Text] [Related]

  • 8. Ingestion of an isothiocyanate metabolite from cruciferous vegetables inhibits growth of human prostate cancer cell xenografts by apoptosis and cell cycle arrest.
    Chiao JW, Wu H, Ramaswamy G, Conaway CC, Chung FL, Wang L, Liu D.
    Carcinogenesis; 2004 Aug 15; 25(8):1403-8. PubMed ID: 15016658
    [Abstract] [Full Text] [Related]

  • 9. Atg5 regulates phenethyl isothiocyanate-induced autophagic and apoptotic cell death in human prostate cancer cells.
    Bommareddy A, Hahm ER, Xiao D, Powolny AA, Fisher AL, Jiang Y, Singh SV.
    Cancer Res; 2009 Apr 15; 69(8):3704-12. PubMed ID: 19336571
    [Abstract] [Full Text] [Related]

  • 10. DNA methylome, transcriptome, and prostate cancer prevention by phenethyl isothiocyanate in TRAMP mice.
    Wu R, Li S, Sargsyan D, Yin R, Kuo HC, Peter R, Wang L, Hudlikar R, Liu X, Kong AN.
    Mol Carcinog; 2021 Jun 15; 60(6):391-402. PubMed ID: 33848375
    [Abstract] [Full Text] [Related]

  • 11. Caspase-dependent apoptosis induction by phenethyl isothiocyanate, a cruciferous vegetable-derived cancer chemopreventive agent, is mediated by Bak and Bax.
    Xiao D, Zeng Y, Choi S, Lew KL, Nelson JB, Singh SV.
    Clin Cancer Res; 2005 Apr 01; 11(7):2670-9. PubMed ID: 15814648
    [Abstract] [Full Text] [Related]

  • 12. Phenethyl isothiocyanate suppresses inhibitor of apoptosis family protein expression in prostate cancer cells in culture and in vivo.
    Sakao K, Desineni S, Hahm ER, Singh SV.
    Prostate; 2012 Jul 01; 72(10):1104-16. PubMed ID: 22161756
    [Abstract] [Full Text] [Related]

  • 13. p53 mutant-type in human prostate cancer cells determines the sensitivity to phenethyl isothiocyanate induced growth inhibition.
    Aggarwal M, Saxena R, Asif N, Sinclair E, Tan J, Cruz I, Berry D, Kallakury B, Pham Q, Wang TTY, Chung FL.
    J Exp Clin Cancer Res; 2019 Jul 15; 38(1):307. PubMed ID: 31307507
    [Abstract] [Full Text] [Related]

  • 14. Combined inhibitory effects of curcumin and phenethyl isothiocyanate on the growth of human PC-3 prostate xenografts in immunodeficient mice.
    Khor TO, Keum YS, Lin W, Kim JH, Hu R, Shen G, Xu C, Gopalakrishnan A, Reddy B, Zheng X, Conney AH, Kong AN.
    Cancer Res; 2006 Jan 15; 66(2):613-21. PubMed ID: 16423986
    [Abstract] [Full Text] [Related]

  • 15. Inhibition of autophagy potentiates the anti-metastasis effect of phenethyl isothiocyanate through JAK2/STAT3 pathway in lung cancer cells.
    Wang H, Wang L, Cao L, Zhang Q, Song Q, Meng Z, Wu X, Xu K.
    Mol Carcinog; 2018 Apr 15; 57(4):522-535. PubMed ID: 29278657
    [Abstract] [Full Text] [Related]

  • 16. Mechanisms of inhibition of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone bioactivation in mouse by dietary phenethyl isothiocyanate.
    Smith TJ, Guo Z, Li C, Ning SM, Thomas PE, Yang CS.
    Cancer Res; 1993 Jul 15; 53(14):3276-82. PubMed ID: 8324738
    [Abstract] [Full Text] [Related]

  • 17. Proteasome-mediated degradation of cell division cycle 25C and cyclin-dependent kinase 1 in phenethyl isothiocyanate-induced G2-M-phase cell cycle arrest in PC-3 human prostate cancer cells.
    Xiao D, Johnson CS, Trump DL, Singh SV.
    Mol Cancer Ther; 2004 May 15; 3(5):567-75. PubMed ID: 15141014
    [Abstract] [Full Text] [Related]

  • 18. Phenethyl isothiocyanate: a comprehensive review of anti-cancer mechanisms.
    Gupta P, Wright SE, Kim SH, Srivastava SK.
    Biochim Biophys Acta; 2014 Dec 15; 1846(2):405-24. PubMed ID: 25152445
    [Abstract] [Full Text] [Related]

  • 19. Phenethyl isothiocyanate (PEITC) promotes G2/M phase arrest via p53 expression and induces apoptosis through caspase- and mitochondria-dependent signaling pathways in human prostate cancer DU 145 cells.
    Tang NY, Huang YT, Yu CS, Ko YC, Wu SH, Ji BC, Yang JS, Yang JL, Hsia TC, Chen YY, Chung JG.
    Anticancer Res; 2011 May 15; 31(5):1691-702. PubMed ID: 21617228
    [Abstract] [Full Text] [Related]

  • 20. Phenethyl isothiocyanate inhibits oxidative phosphorylation to trigger reactive oxygen species-mediated death of human prostate cancer cells.
    Xiao D, Powolny AA, Moura MB, Kelley EE, Bommareddy A, Kim SH, Hahm ER, Normolle D, Van Houten B, Singh SV.
    J Biol Chem; 2010 Aug 20; 285(34):26558-69. PubMed ID: 20571029
    [Abstract] [Full Text] [Related]


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