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297 related items for PubMed ID: 21331764

  • 21. FTY720 inhibits proliferation and epithelial-mesenchymal transition in cholangiocarcinoma by inactivating STAT3 signaling.
    Lu Z, Wang J, Zheng T, Liang Y, Yin D, Song R, Pei T, Pan S, Jiang H, Liu L.
    BMC Cancer; 2014 Oct 25; 14():783. PubMed ID: 25344679
    [Abstract] [Full Text] [Related]

  • 22. Antitumor activity of sorafenib in human cancer cell lines with acquired resistance to EGFR and VEGFR tyrosine kinase inhibitors.
    Morgillo F, Martinelli E, Troiani T, Orditura M, De Vita F, Ciardiello F.
    PLoS One; 2011 Oct 25; 6(12):e28841. PubMed ID: 22174910
    [Abstract] [Full Text] [Related]

  • 23. Sorafenib inhibits growth and mitogen-activated protein kinase signaling in malignant peripheral nerve sheath cells.
    Ambrosini G, Cheema HS, Seelman S, Teed A, Sambol EB, Singer S, Schwartz GK.
    Mol Cancer Ther; 2008 Apr 25; 7(4):890-6. PubMed ID: 18413802
    [Abstract] [Full Text] [Related]

  • 24. Apatinib inhibits VEGF signaling and promotes apoptosis in intrahepatic cholangiocarcinoma.
    Peng H, Zhang Q, Li J, Zhang N, Hua Y, Xu L, Deng Y, Lai J, Peng Z, Peng B, Chen M, Peng S, Kuang M.
    Oncotarget; 2016 Mar 29; 7(13):17220-9. PubMed ID: 26967384
    [Abstract] [Full Text] [Related]

  • 25. Sorafenib decreases proliferation and induces apoptosis of prostate cancer cells by inhibition of the androgen receptor and Akt signaling pathways.
    Oh SJ, Erb HH, Hobisch A, Santer FR, Culig Z.
    Endocr Relat Cancer; 2012 Jun 29; 19(3):305-19. PubMed ID: 22383427
    [Abstract] [Full Text] [Related]

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  • 27. Sorafenib enhances the antitumor effects of chemoradiation treatment by downregulating ERCC-1 and XRCC-1 DNA repair proteins.
    Yadav A, Kumar B, Teknos TN, Kumar P.
    Mol Cancer Ther; 2011 Jul 29; 10(7):1241-51. PubMed ID: 21551262
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  • 29. H3 histamine receptor-mediated activation of protein kinase Calpha inhibits the growth of cholangiocarcinoma in vitro and in vivo.
    Francis H, Onori P, Gaudio E, Franchitto A, DeMorrow S, Venter J, Kopriva S, Carpino G, Mancinelli R, White M, Meng F, Vetuschi A, Sferra R, Alpini G.
    Mol Cancer Res; 2009 Oct 29; 7(10):1704-13. PubMed ID: 19825989
    [Abstract] [Full Text] [Related]

  • 30. YC-1 enhances the anti-tumor activity of sorafenib through inhibition of signal transducer and activator of transcription 3 (STAT3) in hepatocellular carcinoma.
    Kong J, Kong F, Gao J, Zhang Q, Dong S, Gu F, Ke S, Pan B, Shen Q, Sun H, Zheng L, Sun W.
    Mol Cancer; 2014 Jan 13; 13():7. PubMed ID: 24418169
    [Abstract] [Full Text] [Related]

  • 31. BAY 43-9006 exhibits broad spectrum oral antitumor activity and targets the RAF/MEK/ERK pathway and receptor tyrosine kinases involved in tumor progression and angiogenesis.
    Wilhelm SM, Carter C, Tang L, Wilkie D, McNabola A, Rong H, Chen C, Zhang X, Vincent P, McHugh M, Cao Y, Shujath J, Gawlak S, Eveleigh D, Rowley B, Liu L, Adnane L, Lynch M, Auclair D, Taylor I, Gedrich R, Voznesensky A, Riedl B, Post LE, Bollag G, Trail PA.
    Cancer Res; 2004 Oct 01; 64(19):7099-109. PubMed ID: 15466206
    [Abstract] [Full Text] [Related]

  • 32. Sorafenib-induced apoptosis of chronic lymphocytic leukemia cells is associated with downregulation of RAF and myeloid cell leukemia sequence 1 (Mcl-1).
    Fecteau JF, Bharati IS, O'Hayre M, Handel TM, Kipps TJ, Messmer D.
    Mol Med; 2012 Feb 10; 18(1):19-28. PubMed ID: 21979753
    [Abstract] [Full Text] [Related]

  • 33. A novel combination of withaferin A and sorafenib shows synergistic efficacy against both papillary and anaplastic thyroid cancers.
    Cohen SM, Mukerji R, Timmermann BN, Samadi AK, Cohen MS.
    Am J Surg; 2012 Dec 10; 204(6):895-900; discussion 900-1. PubMed ID: 23231932
    [Abstract] [Full Text] [Related]

  • 34. Induction of DNA damage-inducible gene GADD45beta contributes to sorafenib-induced apoptosis in hepatocellular carcinoma cells.
    Ou DL, Shen YC, Yu SL, Chen KF, Yeh PY, Fan HH, Feng WC, Wang CT, Lin LI, Hsu C, Cheng AL.
    Cancer Res; 2010 Nov 15; 70(22):9309-18. PubMed ID: 21062976
    [Abstract] [Full Text] [Related]

  • 35. Signal transducer and activator of transcription 3 is a major kinase-independent target of sorafenib in hepatocellular carcinoma.
    Tai WT, Cheng AL, Shiau CW, Huang HP, Huang JW, Chen PJ, Chen KF.
    J Hepatol; 2011 Nov 15; 55(5):1041-8. PubMed ID: 21354226
    [Abstract] [Full Text] [Related]

  • 36. Role of RAF/MEK/ERK pathway, p-STAT-3 and Mcl-1 in sorafenib activity in human pancreatic cancer cell lines.
    Ulivi P, Arienti C, Amadori D, Fabbri F, Carloni S, Tesei A, Vannini I, Silvestrini R, Zoli W.
    J Cell Physiol; 2009 Jul 15; 220(1):214-21. PubMed ID: 19288493
    [Abstract] [Full Text] [Related]

  • 37. Combination of the ERK inhibitor AZD6244 and low-dose sorafenib in a xenograft model of human renal cell carcinoma.
    Yuen JS, Sim MY, Sim HG, Chong TW, Lau WK, Cheng CW, Ong RW, Huynh H.
    Int J Oncol; 2012 Aug 15; 41(2):712-20. PubMed ID: 22641227
    [Abstract] [Full Text] [Related]

  • 38. Scabraside D Extracted from Holothuria scabra Induces Apoptosis and Inhibits Growth of Human Cholangiocarcinoma Xenografts in Mice.
    Assawasuparerk K, Vanichviriyakit R, Chotwiwatthanakun C, Nobsathian S, Rawangchue T, Wittayachumnankul B.
    Asian Pac J Cancer Prev; 2016 Aug 15; 17(2):511-7. PubMed ID: 26925636
    [Abstract] [Full Text] [Related]

  • 39. Inhibition of Bcl-2 antiapoptotic members by obatoclax potently enhances sorafenib-induced apoptosis in human myeloid leukemia cells through a Bim-dependent process.
    Rahmani M, Aust MM, Attkisson E, Williams DC, Ferreira-Gonzalez A, Grant S.
    Blood; 2012 Jun 21; 119(25):6089-98. PubMed ID: 22446485
    [Abstract] [Full Text] [Related]

  • 40. Sorafenib in combination with ionizing radiation has a greater anti-tumour activity in a breast cancer model.
    Heravi M, Tomic N, Liang L, Devic S, Holmes J, Deblois F, Radzioch D, Muanza T.
    Anticancer Drugs; 2012 Jun 21; 23(5):525-33. PubMed ID: 22357220
    [Abstract] [Full Text] [Related]

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