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Journal Abstract Search

262 related items for PubMed ID: 21343306

  • 1. Membrane-associated ubiquitin ligase complex containing gp78 mediates sterol-accelerated degradation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase.
    Jo Y, Sguigna PV, DeBose-Boyd RA.
    J Biol Chem; 2011 Apr 29; 286(17):15022-31. PubMed ID: 21343306
    [Abstract] [Full Text] [Related]

  • 2. Gp78, a membrane-anchored ubiquitin ligase, associates with Insig-1 and couples sterol-regulated ubiquitination to degradation of HMG CoA reductase.
    Song BL, Sever N, DeBose-Boyd RA.
    Mol Cell; 2005 Sep 16; 19(6):829-40. PubMed ID: 16168377
    [Abstract] [Full Text] [Related]

  • 3. Sterol-induced degradation of HMG CoA reductase depends on interplay of two Insigs and two ubiquitin ligases, gp78 and Trc8.
    Jo Y, Lee PC, Sguigna PV, DeBose-Boyd RA.
    Proc Natl Acad Sci U S A; 2011 Dec 20; 108(51):20503-8. PubMed ID: 22143767
    [Abstract] [Full Text] [Related]

  • 4. Ancient ubiquitous protein-1 mediates sterol-induced ubiquitination of 3-hydroxy-3-methylglutaryl CoA reductase in lipid droplet-associated endoplasmic reticulum membranes.
    Jo Y, Hartman IZ, DeBose-Boyd RA.
    Mol Biol Cell; 2013 Feb 20; 24(3):169-83. PubMed ID: 23223569
    [Abstract] [Full Text] [Related]

  • 5. Ring finger protein 145 (RNF145) is a ubiquitin ligase for sterol-induced degradation of HMG-CoA reductase.
    Jiang LY, Jiang W, Tian N, Xiong YN, Liu J, Wei J, Wu KY, Luo J, Shi XJ, Song BL.
    J Biol Chem; 2018 Mar 16; 293(11):4047-4055. PubMed ID: 29374057
    [Abstract] [Full Text] [Related]

  • 6. Sterol-regulated degradation of Insig-1 mediated by the membrane-bound ubiquitin ligase gp78.
    Lee JN, Song B, DeBose-Boyd RA, Ye J.
    J Biol Chem; 2006 Dec 22; 281(51):39308-15. PubMed ID: 17043353
    [Abstract] [Full Text] [Related]

  • 7. Control of cholesterol synthesis through regulated ER-associated degradation of HMG CoA reductase.
    Jo Y, Debose-Boyd RA.
    Crit Rev Biochem Mol Biol; 2010 Jun 22; 45(3):185-98. PubMed ID: 20482385
    [Abstract] [Full Text] [Related]

  • 8. gp78 functions downstream of Hrd1 to promote degradation of misfolded proteins of the endoplasmic reticulum.
    Zhang T, Xu Y, Liu Y, Ye Y.
    Mol Biol Cell; 2015 Dec 01; 26(24):4438-50. PubMed ID: 26424800
    [Abstract] [Full Text] [Related]

  • 9. Insig-mediated, sterol-accelerated degradation of the membrane domain of hamster 3-hydroxy-3-methylglutaryl-coenzyme A reductase in insect cells.
    Nguyen AD, Lee SH, DeBose-Boyd RA.
    J Biol Chem; 2009 Sep 25; 284(39):26778-88. PubMed ID: 19638338
    [Abstract] [Full Text] [Related]

  • 10. The sterol-responsive RNF145 E3 ubiquitin ligase mediates the degradation of HMG-CoA reductase together with gp78 and Hrd1.
    Menzies SA, Volkmar N, van den Boomen DJ, Timms RT, Dickson AS, Nathan JA, Lehner PJ.
    Elife; 2018 Dec 13; 7():. PubMed ID: 30543180
    [Abstract] [Full Text] [Related]

  • 11. Differential regulation of HMG-CoA reductase and Insig-1 by enzymes of the ubiquitin-proteasome system.
    Tsai YC, Leichner GS, Pearce MM, Wilson GL, Wojcikiewicz RJ, Roitelman J, Weissman AM.
    Mol Biol Cell; 2012 Dec 13; 23(23):4484-94. PubMed ID: 23087214
    [Abstract] [Full Text] [Related]

  • 12. In vivo action of the HRD ubiquitin ligase complex: mechanisms of endoplasmic reticulum quality control and sterol regulation.
    Gardner RG, Shearer AG, Hampton RY.
    Mol Cell Biol; 2001 Jul 13; 21(13):4276-91. PubMed ID: 11390656
    [Abstract] [Full Text] [Related]

  • 13. Different p97/VCP complexes function in retrotranslocation step of mammalian ER-associated degradation (ERAD).
    Ballar P, Pabuccuoglu A, Kose FA.
    Int J Biochem Cell Biol; 2011 Apr 13; 43(4):613-21. PubMed ID: 21199683
    [Abstract] [Full Text] [Related]

  • 14. Ufd1 is a cofactor of gp78 and plays a key role in cholesterol metabolism by regulating the stability of HMG-CoA reductase.
    Cao J, Wang J, Qi W, Miao HH, Wang J, Ge L, DeBose-Boyd RA, Tang JJ, Li BL, Song BL.
    Cell Metab; 2007 Aug 13; 6(2):115-28. PubMed ID: 17681147
    [Abstract] [Full Text] [Related]

  • 15. Gp78 cooperates with RMA1 in endoplasmic reticulum-associated degradation of CFTRDeltaF508.
    Morito D, Hirao K, Oda Y, Hosokawa N, Tokunaga F, Cyr DM, Tanaka K, Iwai K, Nagata K.
    Mol Biol Cell; 2008 Apr 13; 19(4):1328-36. PubMed ID: 18216283
    [Abstract] [Full Text] [Related]

  • 16. Targeting of gp78 for ubiquitin-mediated proteasomal degradation by Hrd1: cross-talk between E3s in the endoplasmic reticulum.
    Shmueli A, Tsai YC, Yang M, Braun MA, Weissman AM.
    Biochem Biophys Res Commun; 2009 Dec 18; 390(3):758-62. PubMed ID: 19835843
    [Abstract] [Full Text] [Related]

  • 17. Ubiquitination of 3-hydroxy-3-methylglutaryl-CoA reductase in permeabilized cells mediated by cytosolic E1 and a putative membrane-bound ubiquitin ligase.
    Song BL, DeBose-Boyd RA.
    J Biol Chem; 2004 Jul 02; 279(27):28798-806. PubMed ID: 15090540
    [Abstract] [Full Text] [Related]

  • 18. Sterol-induced dislocation of 3-hydroxy-3-methylglutaryl coenzyme A reductase from membranes of permeabilized cells.
    Elsabrouty R, Jo Y, Dinh TT, DeBose-Boyd RA.
    Mol Biol Cell; 2013 Nov 02; 24(21):3300-8. PubMed ID: 24025715
    [Abstract] [Full Text] [Related]

  • 19. The tumor autocrine motility factor receptor, gp78, is a ubiquitin protein ligase implicated in degradation from the endoplasmic reticulum.
    Fang S, Ferrone M, Yang C, Jensen JP, Tiwari S, Weissman AM.
    Proc Natl Acad Sci U S A; 2001 Dec 04; 98(25):14422-7. PubMed ID: 11724934
    [Abstract] [Full Text] [Related]

  • 20. Lipid-regulated degradation of HMG-CoA reductase and Insig-1 through distinct mechanisms in insect cells.
    Faulkner RA, Nguyen AD, Jo Y, DeBose-Boyd RA.
    J Lipid Res; 2013 Apr 04; 54(4):1011-22. PubMed ID: 23403031
    [Abstract] [Full Text] [Related]

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