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1107 related items for PubMed ID: 21344160

  • 1. The novel synthesized 2-(3-(methylamino)phenyl)-6-(pyrrolidin-1-yl)quinolin-4-one (Smh-3) compound induces G2/M phase arrest and mitochondrial-dependent apoptotic cell death through inhibition of CDK1 and AKT activity in HL-60 human leukemia cells.
    Huang SM, Yang JS, Tsai SC, Chen MH, Hsu MH, Lin HY, Chou LC, Chinag JH, Lee KH, Huang LJ, Kuo SC.
    Int J Oncol; 2011 May; 38(5):1357-64. PubMed ID: 21344160
    [Abstract] [Full Text] [Related]

  • 2. Selective induction of G2/M arrest and apoptosis in HL-60 by a potent anticancer agent, HMJ-38.
    Yang JS, Hour MJ, Kuo SC, Huang LJ, Lee MR.
    Anticancer Res; 2004 May; 24(3a):1769-78. PubMed ID: 15274354
    [Abstract] [Full Text] [Related]

  • 3. MJ-29 inhibits tubulin polymerization, induces mitotic arrest, and triggers apoptosis via cyclin-dependent kinase 1-mediated Bcl-2 phosphorylation in human leukemia U937 cells.
    Yang JS, Hour MJ, Huang WW, Lin KL, Kuo SC, Chung JG.
    J Pharmacol Exp Ther; 2010 Aug; 334(2):477-88. PubMed ID: 20463006
    [Abstract] [Full Text] [Related]

  • 4. Cantharidin induces G2/M phase arrest and apoptosis in human colorectal cancer colo 205 cells through inhibition of CDK1 activity and caspase-dependent signaling pathways.
    Huang WW, Ko SW, Tsai HY, Chung JG, Chiang JH, Chen KT, Chen YC, Chen HY, Chen YF, Yang JS.
    Int J Oncol; 2011 Apr; 38(4):1067-73. PubMed ID: 21271215
    [Abstract] [Full Text] [Related]

  • 5. Morin inhibits the growth of human leukemia HL-60 cells via cell cycle arrest and induction of apoptosis through mitochondria dependent pathway.
    Kuo HM, Chang LS, Lin YL, Lu HF, Yang JS, Lee JH, Chung JG.
    Anticancer Res; 2007 Apr; 27(1A):395-405. PubMed ID: 17352259
    [Abstract] [Full Text] [Related]

  • 6. The induction of G2/M cell-cycle arrest and apoptosis by cucurbitacin E is associated with increased phosphorylation of eIF2alpha in leukemia cells.
    Li Y, Wang R, Ma E, Deng Y, Wang X, Xiao J, Jing Y.
    Anticancer Drugs; 2010 Apr; 21(4):389-400. PubMed ID: 20110807
    [Abstract] [Full Text] [Related]

  • 7. Smh-3 induces G(2)/M arrest and apoptosis through calcium‑mediated endoplasmic reticulum stress and mitochondrial signaling in human hepatocellular carcinoma Hep3B cells.
    Liu CY, Yang JS, Huang SM, Chiang JH, Chen MH, Huang LJ, Ha HY, Fushiya S, Kuo SC.
    Oncol Rep; 2013 Feb; 29(2):751-62. PubMed ID: 23233035
    [Abstract] [Full Text] [Related]

  • 8. Apoptosis of human leukemia HL-60 cells and murine leukemia WEHI-3 cells induced by berberine through the activation of caspase-3.
    Lin CC, Kao ST, Chen GW, Ho HC, Chung JG.
    Anticancer Res; 2006 Feb; 26(1A):227-42. PubMed ID: 16475703
    [Abstract] [Full Text] [Related]

  • 9. Induction of mitotic arrest and apoptosis by a novel synthetic quinolone analogue, CWC-8, via intrinsic and extrinsic apoptotic pathways in human osteogenic sarcoma U-2 OS cells.
    Chang YH, Yang JS, Kuo SC, Chung JG.
    Anticancer Res; 2009 Aug; 29(8):3139-48. PubMed ID: 19661327
    [Abstract] [Full Text] [Related]

  • 10. Benzyl isothiocyanate (BITC) induces G2/M phase arrest and apoptosis in human melanoma A375.S2 cells through reactive oxygen species (ROS) and both mitochondria-dependent and death receptor-mediated multiple signaling pathways.
    Huang SH, Wu LW, Huang AC, Yu CC, Lien JC, Huang YP, Yang JS, Yang JH, Hsiao YP, Wood WG, Yu CS, Chung JG.
    J Agric Food Chem; 2012 Jan 18; 60(2):665-75. PubMed ID: 22148415
    [Abstract] [Full Text] [Related]

  • 11. [Induction of G2 /M phase arrest and apoptosis of MCF-7 cells by novel benzofuran lignan via suppressing cell cycle proteins].
    Yang H, Cai YC, Pang JY, Li YQ, Zeng ZL, Xu ZL, Xian LJ.
    Yao Xue Xue Bao; 2008 Feb 18; 43(2):138-44. PubMed ID: 18507339
    [Abstract] [Full Text] [Related]

  • 12. The newly synthesized 2-(3-hydroxy-5-methoxyphenyl)-6,7-methylenedioxyquinolin-4-one triggers cell apoptosis through induction of oxidative stress and upregulation of the p38 MAPK signaling pathway in HL-60 human leukemia cells.
    Cheng YY, Yang JS, Tsai SC, Liaw CC, Chung JG, Huang LJ, Lee KH, Lu CC, Chien HC, Tsuzuki M, Kuo SC.
    Oncol Rep; 2012 Oct 18; 28(4):1482-90. PubMed ID: 22825350
    [Abstract] [Full Text] [Related]

  • 13. The histone deacetylase inhibitor MS-275 promotes differentiation or apoptosis in human leukemia cells through a process regulated by generation of reactive oxygen species and induction of p21CIP1/WAF1 1.
    Rosato RR, Almenara JA, Grant S.
    Cancer Res; 2003 Jul 01; 63(13):3637-45. PubMed ID: 12839953
    [Abstract] [Full Text] [Related]

  • 14. Apoptosis-inducing active components from Corbicula fluminea through activation of caspase-2 and production of reactive oxygen species in human leukemia HL-60 cells.
    Huang YT, Huang YH, Hour TC, Pan BS, Liu YC, Pan MH.
    Food Chem Toxicol; 2006 Aug 01; 44(8):1261-72. PubMed ID: 16545898
    [Abstract] [Full Text] [Related]

  • 15. 7-Chloro-6-piperidin-1-yl-quinoline-5,8-dione (PT-262), a novel synthetic compound induces lung carcinoma cell death associated with inhibiting ERK and CDC2 phosphorylation via a p53-independent pathway.
    Hsu TS, Chen C, Lee PT, Chiu SJ, Liu HF, Tsai CC, Chao JI.
    Cancer Chemother Pharmacol; 2008 Oct 01; 62(5):799-808. PubMed ID: 18193228
    [Abstract] [Full Text] [Related]

  • 16. Induction of caspase-3-dependent apoptosis in human leukemia HL-60 cells by paclitaxel.
    Lu KH, Lue KH, Liao HH, Lin KL, Chung JG.
    Clin Chim Acta; 2005 Jul 01; 357(1):65-73. PubMed ID: 15963795
    [Abstract] [Full Text] [Related]

  • 17. Andrographolide induces cell cycle arrest at G2/M phase and cell death in HepG2 cells via alteration of reactive oxygen species.
    Li J, Cheung HY, Zhang Z, Chan GK, Fong WF.
    Eur J Pharmacol; 2007 Jul 30; 568(1-3):31-44. PubMed ID: 17512926
    [Abstract] [Full Text] [Related]

  • 18. Hydroxylation at C4' or C6 is essential for apoptosis-inducing activity of flavanone through activation of the caspase-3 cascade and production of reactive oxygen species.
    Ko CH, Shen SC, Chen YC.
    Free Radic Biol Med; 2004 Apr 01; 36(7):897-910. PubMed ID: 15019974
    [Abstract] [Full Text] [Related]

  • 19. Quinolone analogue inhibits tubulin polymerization and induces apoptosis via Cdk1-involved signaling pathways.
    Chen YC, Lu PH, Pan SL, Teng CM, Kuo SC, Lin TP, Ho YF, Huang YC, Guh JH.
    Biochem Pharmacol; 2007 Jun 30; 74(1):10-9. PubMed ID: 17475221
    [Abstract] [Full Text] [Related]

  • 20. Involvement of c-jun N-terminal kinase in G2/M arrest and caspase-mediated apoptosis induced by cardiotoxin III (Naja naja atra) in K562 leukemia cells.
    Yang SH, Chien CM, Chang LS, Lin SR.
    Toxicon; 2007 Jun 01; 49(7):966-74. PubMed ID: 17368702
    [Abstract] [Full Text] [Related]

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