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Journal Abstract Search

77 related items for PubMed ID: 21345314

  • 1. Effects of chronic alcohol consumption on expression levels of APP and Aβ-producing enzymes.
    Kim SR, Jeong HY, Yang S, Choi SP, Seo MY, Yun YK, Choi Y, Baik SH, Park JS, Gwon AR, Yang DK, Lee CH, Lee SM, Park KW, Jo DG.
    BMB Rep; 2011 Feb; 44(2):135-9. PubMed ID: 21345314
    [Abstract] [Full Text] [Related]

  • 2. Beta-amyloid secretases and beta-amloid degrading enzyme expression in lens.
    Li G, Percontino L, Sun Q, Qazi AS, Frederikse PH.
    Mol Vis; 2003 May 01; 9():179-83. PubMed ID: 12740567
    [Abstract] [Full Text] [Related]

  • 3. S-Adenosylhomocysteine increases beta-amyloid formation in BV-2 microglial cells by increased expressions of beta-amyloid precursor protein and presenilin 1 and by hypomethylation of these gene promoters.
    Lin HC, Hsieh HM, Chen YH, Hu ML.
    Neurotoxicology; 2009 Jul 01; 30(4):622-7. PubMed ID: 19635394
    [Abstract] [Full Text] [Related]

  • 4. Thiamine deficiency increases β-secretase activity and accumulation of β-amyloid peptides.
    Zhang Q, Yang G, Li W, Fan Z, Sun A, Luo J, Ke ZJ.
    Neurobiol Aging; 2011 Jan 01; 32(1):42-53. PubMed ID: 19233513
    [Abstract] [Full Text] [Related]

  • 5. The proteins BACE1 and BACE2 and beta-secretase activity in normal and Alzheimer's disease brain.
    Stockley JH, O'Neill C.
    Biochem Soc Trans; 2007 Jun 01; 35(Pt 3):574-6. PubMed ID: 17511655
    [Abstract] [Full Text] [Related]

  • 6. LRRTM3 promotes processing of amyloid-precursor protein by BACE1 and is a positional candidate gene for late-onset Alzheimer's disease.
    Majercak J, Ray WJ, Espeseth A, Simon A, Shi XP, Wolffe C, Getty K, Marine S, Stec E, Ferrer M, Strulovici B, Bartz S, Gates A, Xu M, Huang Q, Ma L, Shughrue P, Burchard J, Colussi D, Pietrak B, Kahana J, Beher D, Rosahl T, Shearman M, Hazuda D, Sachs AB, Koblan KS, Seabrook GR, Stone DJ.
    Proc Natl Acad Sci U S A; 2006 Nov 21; 103(47):17967-72. PubMed ID: 17098871
    [Abstract] [Full Text] [Related]

  • 7. Excess of nicastrin in brain results in heterozygosity having no effect on endogenous APP processing and amyloid peptide levels in vivo.
    Brijbassi S, Amtul Z, Newbigging S, Westaway D, St George-Hyslop P, Rozmahel RF.
    Neurobiol Dis; 2007 Feb 21; 25(2):291-6. PubMed ID: 17071095
    [Abstract] [Full Text] [Related]

  • 8. Measurement of cellular beta-site of APP cleaving enzyme 1 activity and its modulation in neuronal assay systems.
    Volbracht C, Penzkofer S, Mansson D, Christensen KV, Fog K, Schildknecht S, Leist M, Nielsen J.
    Anal Biochem; 2009 Apr 15; 387(2):208-20. PubMed ID: 19454261
    [Abstract] [Full Text] [Related]

  • 9. Proteolytic processing of the Alzheimer's disease amyloid precursor protein in brain and platelets.
    Evin G, Zhu A, Holsinger RM, Masters CL, Li QX.
    J Neurosci Res; 2003 Nov 01; 74(3):386-92. PubMed ID: 14598315
    [Abstract] [Full Text] [Related]

  • 10. In vivo beta-secretase 1 inhibition leads to brain Abeta lowering and increased alpha-secretase processing of amyloid precursor protein without effect on neuregulin-1.
    Sankaranarayanan S, Price EA, Wu G, Crouthamel MC, Shi XP, Tugusheva K, Tyler KX, Kahana J, Ellis J, Jin L, Steele T, Stachel S, Coburn C, Simon AJ.
    J Pharmacol Exp Ther; 2008 Mar 01; 324(3):957-69. PubMed ID: 18156464
    [Abstract] [Full Text] [Related]

  • 11. Presenilin 1 is involved in the maturation of beta-site amyloid precursor protein-cleaving enzyme 1 (BACE1).
    Kuzuya A, Uemura K, Kitagawa N, Aoyagi N, Kihara T, Ninomiya H, Ishiura S, Takahashi R, Shimohama S.
    J Neurosci Res; 2007 Jan 01; 85(1):153-65. PubMed ID: 17075903
    [Abstract] [Full Text] [Related]

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  • 13. Thymoquinone-rich fraction nanoemulsion (TQRFNE) decreases Aβ40 and Aβ42 levels by modulating APP processing, up-regulating IDE and LRP1, and down-regulating BACE1 and RAGE in response to high fat/cholesterol diet-induced rats.
    Ismail N, Ismail M, Azmi NH, Bakar MFA, Yida Z, Abdullah MA, Basri H.
    Biomed Pharmacother; 2017 Nov 01; 95():780-788. PubMed ID: 28892789
    [Abstract] [Full Text] [Related]

  • 14. The role of low-density receptor-related protein 1 (LRP1) as a competitive substrate of the amyloid precursor protein (APP) for BACE1.
    von Einem B, Schwanzar D, Rehn F, Beyer AS, Weber P, Wagner M, Schneckenburger H, von Arnim CA.
    Exp Neurol; 2010 Sep 01; 225(1):85-93. PubMed ID: 20685197
    [Abstract] [Full Text] [Related]

  • 15. BACE1 inhibition reduces endogenous Abeta and alters APP processing in wild-type mice.
    Nishitomi K, Sakaguchi G, Horikoshi Y, Gray AJ, Maeda M, Hirata-Fukae C, Becker AG, Hosono M, Sakaguchi I, Minami SS, Nakajima Y, Li HF, Takeyama C, Kihara T, Ota A, Wong PC, Aisen PS, Kato A, Kinoshita N, Matsuoka Y.
    J Neurochem; 2006 Dec 01; 99(6):1555-63. PubMed ID: 17083447
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  • 17. The novel beta-secretase inhibitor KMI-429 reduces amyloid beta peptide production in amyloid precursor protein transgenic and wild-type mice.
    Asai M, Hattori C, Iwata N, Saido TC, Sasagawa N, Szabó B, Hashimoto Y, Maruyama K, Tanuma S, Kiso Y, Ishiura S.
    J Neurochem; 2006 Jan 01; 96(2):533-40. PubMed ID: 16336629
    [Abstract] [Full Text] [Related]

  • 18. APP processing is regulated by cytoplasmic phosphorylation.
    Lee MS, Kao SC, Lemere CA, Xia W, Tseng HC, Zhou Y, Neve R, Ahlijanian MK, Tsai LH.
    J Cell Biol; 2003 Oct 13; 163(1):83-95. PubMed ID: 14557249
    [Abstract] [Full Text] [Related]

  • 19. Oral administration of a potent and selective non-peptidic BACE-1 inhibitor decreases beta-cleavage of amyloid precursor protein and amyloid-beta production in vivo.
    Hussain I, Hawkins J, Harrison D, Hille C, Wayne G, Cutler L, Buck T, Walter D, Demont E, Howes C, Naylor A, Jeffrey P, Gonzalez MI, Dingwall C, Michel A, Redshaw S, Davis JB.
    J Neurochem; 2007 Feb 13; 100(3):802-9. PubMed ID: 17156133
    [Abstract] [Full Text] [Related]

  • 20. Effect of heparin on APP metabolism and Abeta production in cortical neurons.
    Klaver D, Hung AC, Gasperini R, Foa L, Aguilar MI, Small DH.
    Neurodegener Dis; 2010 Feb 13; 7(1-3):187-9. PubMed ID: 20224283
    [Abstract] [Full Text] [Related]

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